Accelerated loss of hearing and vision in the DNA-repair deficient Ercc1 δ/- mouse

Mechanisms of Ageing and Development

Volumn 133, Issue 2-3, 2012, Pages 59-67

  Spoor, Marcella ^a   Nagtegaal, A Paul ^a   Ridwan, Yanto ^a   Borgesius, Nils Z ^a   van Alphen, Bart ^a   van der Pluijm, Ingrid ^a   Hoeijmakers, Jan H J ^a   Frens, Maarten A ^a   Borst, J Gerard G ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

DNA repair; Ercc1 ; Presbycusis; Visual system

Indexed keywords

AGE DISTRIBUTION; AGING; ALLELE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUDITORY SYSTEM FUNCTION; AUDITORY THRESHOLD; CARBOXY TERMINAL SEQUENCE; COCHLEA POTENTIAL; CONTRAST SENSITIVITY; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; DISORDERS OF DNA SYNTHESIS AND REPAIR; DNA CROSS LINKING; DNA DAMAGE; DNA HELIX; DOUBLE STRANDED DNA BREAK; EXCISION REPAIR; EYE MOVEMENT; EYEBALL; GENE ACTIVITY; HEARING LOSS; MOUSE; MUTANT; NONHUMAN; PHOTORECEPTOR CELL; PRESBYACUSIS; PRIORITY JOURNAL; SEGREGATION DISTORTION; VISUAL IMPAIRMENT; VISUAL SYSTEM FUNCTION; WILD TYPE;

AGING; ANIMALS; CROSS-LINKING REAGENTS; DNA; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; ELECTRODES; ENDONUCLEASES; HEARING; HEARING LOSS; IMMUNOHISTOCHEMISTRY; MICE; MUTATION; OTOACOUSTIC EMISSIONS, SPONTANEOUS; SACCADES; VISION DISORDERS; VISION, OCULAR;

MUS;

EID: 84857783964     PISSN: 00476374     EISSN: 18726216     Source Type: Journal    
DOI: 10.1016/j.mad.2011.12.003     Document Type: Article

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