-
1
-
-
0000524684
-
On the treatment of inoperable cases carcinogen of the mamma: Suggestions for a new method of treatment, with illustrative cases
-
Beatson, G.T. On the treatment of inoperable cases carcinogen of the mamma: suggestions for a new method of treatment, with illustrative cases. Lancet, 1896, 2, 105-107.
-
(1896)
Lancet
, vol.2
, pp. 105-107
-
-
Beatson, G.T.1
-
2
-
-
71049135731
-
Synthesis and antitumor activities of 3- modified 2-methoxyestradiol analogs
-
Suwandi, L.S.; Agoston, G.E.; Shah, J.H.; Hanson, A.D.; Zhan, X.H.; Lavallee, T.M.; Treston, A.M. Synthesis and antitumor activities of 3- modified 2-methoxyestradiol analogs. Bioorg. Med. Chem. Lett., 2009, 19, 6459-6462.
-
(2009)
Bioorg. Med. Chem. Lett
, vol.19
, pp. 6459-6462
-
-
Suwandi, L.S.1
Agoston, G.E.2
Shah, J.H.3
Hanson, A.D.4
Zhan, X.H.5
Lavallee, T.M.6
Treston, A.M.7
-
3
-
-
77951295505
-
Synthesis of 17 alpha-substituted ethynylestradiols: Potential ligands for drug vectors
-
Yaya, A.R.; Touaibia, M.; Massarweh, G.; Rochon, F.D.; Breau, L. Synthesis of 17 alpha-substituted ethynylestradiols: potential ligands for drug vectors. Steroids, 2010, 75, 489-498.
-
(2010)
Steroids
, vol.75
, pp. 489-498
-
-
Yaya, A.R.1
Touaibia, M.2
Massarweh, G.3
Rochon, F.D.4
Breau, L.5
-
4
-
-
0034884460
-
Synthesis and biological evaluation of novel daunorubicin-estrogen conjugates
-
Kasiotis, K.M.; Magiatis, P.; Pratsinis, H.; Skaltsounis, A.; Abadji, V.; Charalambous, A.; Moutsatsou, P., Haroutounian, S.A. Synthesis and biological evaluation of novel daunorubicin-estrogen conjugates. Steroids, 2001, 66, 785-791.
-
(2001)
Steroids
, vol.66
, pp. 785-791
-
-
Kasiotis, K.M.1
Magiatis, P.2
Pratsinis, H.3
Skaltsounis, A.4
Abadji, V.5
Charalambous, A.6
Moutsatsou, P.7
Haroutounian, S.A.8
-
5
-
-
32144447789
-
High affinity 17alpha-substituted estradiol derivatives: Synthesis and evaluation of estrogen receptor agonist activity
-
Kasiotis, K.M.; Mendorou, C.; Haroutounian, S.A.; Alexis, M.N. High affinity 17alpha-substituted estradiol derivatives: synthesis and evaluation of estrogen receptor agonist activity. Steroids, 2006, 71, 249-255.
-
(2006)
Steroids
, vol.71
, pp. 249-255
-
-
Kasiotis, K.M.1
Mendorou, C.2
Haroutounian, S.A.3
Alexis, M.N.4
-
6
-
-
0026395885
-
A potent specific pure antiestrogen with clinical potential
-
Wakeling, A.E.; Dukes, M.; Bowler, J. A potent specific pure antiestrogen with clinical potential. Cancer. Res., 1991, 51, 3867-3873.
-
(1991)
Cancer. Res
, vol.51
, pp. 3867-3873
-
-
Wakeling, A.E.1
Dukes, M.2
Bowler, J.3
-
7
-
-
13244290109
-
Endocrine treatment options for advanced breast cancer--the role of fulvestrant
-
Robertson, J.F.; Come, S.E.; Jones, S.E.; Beex, L.; Kaufmann, M.; Makris, A.; Nortier, J.W.; Possinger, K.; Rutqvist, L.E. Endocrine treatment options for advanced breast cancer--the role of fulvestrant. Eur. J. Cancer, 2005, 41, 346-356.
-
(2005)
Eur. J. Cancer
, vol.41
, pp. 346-356
-
-
Robertson, J.F.1
Come, S.E.2
Jones, S.E.3
Beex, L.4
Kaufmann, M.5
Makris, A.6
Nortier, J.W.7
Possinger, K.8
Rutqvist, L.E.9
-
8
-
-
53649104635
-
The influence of endocrine treatments for breast cancer on health-related quality of life
-
Buijs, C.; de Vries, E.G.; Mourits, M.J.; Willemse, P.H. The influence of endocrine treatments for breast cancer on health-related quality of life. Cancer Treat. Rev., 2008, 34, 640-655.
-
(2008)
Cancer Treat. Rev
, vol.34
, pp. 640-655
-
-
Buijs, C.1
de Vries, E.G.2
Mourits, M.J.3
Willemse, P.H.4
-
10
-
-
34248350428
-
Medicinal chemistry and emerging strategies applied to the development of selective estrogen receptor modulators (SERMs)
-
Musa, M.A., Khan, M.O.F., Cooperwood, J.S. Medicinal chemistry and emerging strategies applied to the development of selective estrogen receptor modulators (SERMs). Curr. Med. Chem., 2011 14, 1249-1261.
-
(2011)
Curr. Med. Chem
, vol.14
, pp. 1249-1261
-
-
Musa, M.A.1
Khan, M.O.F.2
Cooperwood, J.S.3
-
11
-
-
79952778722
-
Structure-Based Approach for the Discovery of Novel Selective Estrogen Receptor Modulators
-
Rosano, C., Stec-Martyna, E., Lappano, R., Maggiolini, M. Structure-Based Approach for the Discovery of Novel Selective Estrogen Receptor Modulators. Curr. Med. Chem., 2011, 18, 1188-1194.
-
(2011)
Curr. Med. Chem
, vol.18
, pp. 1188-1194
-
-
Rosano, C.1
Stec-Martyna, E.2
Lappano, R.3
Maggiolini, M.4
-
12
-
-
0036373440
-
SERMs: Evolutionary chemistry, revolutionary biology
-
Miller C.P. SERMs: Evolutionary chemistry, revolutionary biology. Curr. Pharm. Design, 2002, 8, 2089-2111.
-
(2002)
Curr. Pharm. Design
, vol.8
, pp. 2089-2111
-
-
Miller, C.P.1
-
13
-
-
1642360838
-
The potent triaryiethylene pharmacophore
-
Ray, S., Sangita. The potent triaryiethylene pharmacophore. Drugs of the Future, 2004, 29, 185-203.
-
(2004)
Drugs of the Future
, vol.29
, pp. 185-203
-
-
Ray, S.1
Sangita2
-
14
-
-
27844511538
-
Selective estrogen receptor modulators (SERMs): Mechanisms of anticarcinogenesis and drug resistance
-
Lewis, J.S.; Jordan, V.C. Selective estrogen receptor modulators (SERMs): mechanisms of anticarcinogenesis and drug resistance. Mutat. Res., 2005, 591, 247-263.
-
(2005)
Mutat. Res
, vol.591
, pp. 247-263
-
-
Lewis, J.S.1
Jordan, V.C.2
-
15
-
-
0037435046
-
Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. Part 1. Receptor interactions
-
Jordan, V.C. Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. Part 1. Receptor interactions. J. Med. Chem., 2003, 46, 883-908.
-
(2003)
J. Med. Chem
, vol.46
, pp. 883-908
-
-
Jordan, V.C.1
-
16
-
-
0037468902
-
Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. Part 2. Clinical Considerations and New Agents
-
Jordan, V.C. Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. Part 2. Clinical considerations and new agents J. Med. Chem., 2003, 46, 1081-1111.
-
(2003)
J. Med. Chem
, vol.46
, pp. 1081-1111
-
-
Jordan, V.C.1
-
18
-
-
0037364074
-
Tamoxifen: A most unlikely pioneering medicine
-
Jordan, V.C. Tamoxifen: A most unlikely pioneering medicine. Nat. Rev. Drug Discov. 2003, 2, 205-213.
-
(2003)
Nat. Rev. Drug Discov
, vol.2
, pp. 205-213
-
-
Jordan, V.C.1
-
19
-
-
0029160131
-
Derivatives of 4-styrylpyridines: Synthesis, estrogen receptor binding affinity, and photophysical properties
-
Haroutounian, S.A.; Scribner, A.W.; Katzenellenbogen, J.A. Derivatives of 4-styrylpyridines: synthesis, estrogen receptor binding affinity, and photophysical properties. Steroids, 1995, 60, 636-645.
-
(1995)
Steroids
, vol.60
, pp. 636-645
-
-
Haroutounian, S.A.1
Scribner, A.W.2
Katzenellenbogen, J.A.3
-
20
-
-
0030459216
-
Estrogenic triarylethylene acetic acids: Effect of structural variation on estrogen receptor affinity and estrogenic potency and efficacy in MCF-7 cells
-
Ruenitz, P.C.; Bourne, C.S.; Sullivan, K.J.; Moore, S.A. Estrogenic triarylethylene acetic acids: effect of structural variation on estrogen receptor affinity and estrogenic potency and efficacy in MCF-7 cells. J. Med. Chem., 1996, 39, 4853-4859.
-
(1996)
J. Med. Chem
, vol.39
, pp. 4853-4859
-
-
Ruenitz, P.C.1
Bourne, C.S.2
Sullivan, K.J.3
Moore, S.A.4
-
21
-
-
0037153283
-
Investigations on estrogen receptor binding. The estrogenic, antiestrogenic, and cytotoxic properties of C2-alkylsubstituted 1,1-bis(4-hydroxyphenyl)-2-phenylethenes
-
Lubczyk, V.; Bachmann, H.; Gust, R. Investigations on estrogen receptor binding. The estrogenic, antiestrogenic, and cytotoxic properties of C2-alkylsubstituted 1,1-bis(4-hydroxyphenyl)-2-phenylethenes. J. Med. Chem., 2002, 45, 5358-5364.
-
(2002)
J. Med. Chem
, vol.45
, pp. 5358-5364
-
-
Lubczyk, V.1
Bachmann, H.2
Gust, R.3
-
22
-
-
0037431405
-
Antiestrogenically active 1,1,2-tris(4- hydroxyphenyl)alkenes without basic side chain: Synthesis and biological activity
-
Lubczyk, V.; Bachmann, H.; Gust, R. Antiestrogenically active 1,1,2-tris(4- hydroxyphenyl)alkenes without basic side chain: synthesis and biological activity. J Med. Chem., 2003, 46, 1484-1491.
-
(2003)
J Med. Chem
, vol.46
, pp. 1484-1491
-
-
Lubczyk, V.1
Bachmann, H.2
Gust, R.3
-
23
-
-
0034936607
-
Identification of new triarylethylene oxyalkanoic acid analogues as bone selective estrogen mimetics
-
Rubin, V.N.; Ruenitz, P.C.; Boudinot, F.D.; Boyd, J.L. Identification of new triarylethylene oxyalkanoic acid analogues as bone selective estrogen mimetics. Bioorg. Med. Chem., 2001, 9, 1579-1587.
-
(2001)
Bioorg. Med. Chem
, vol.9
, pp. 1579-1587
-
-
Rubin, V.N.1
Ruenitz, P.C.2
Boudinot, F.D.3
Boyd, J.L.4
-
24
-
-
0037090988
-
Characterization of selective estrogen receptor modulator (SERM) activity in two triarylethylene oxybutyric acids
-
Rubin, V.N.; Ruenitz, P.C.; Boyd, J.L.; Boudinot, F.D., Wiese, T.E. Characterization of selective estrogen receptor modulator (SERM) activity in two triarylethylene oxybutyric acids. Biochem. Pharmacol., 2002, 63, 1517-1525.
-
(2002)
Biochem. Pharmacol
, vol.63
, pp. 1517-1525
-
-
Rubin, V.N.1
Ruenitz, P.C.2
Boyd, J.L.3
Boudinot, F.D.4
Wiese, T.E.5
-
25
-
-
58449118545
-
Synthesis and structure-activity relationships of ferrocenyl tamoxifen derivatives with modified side chains
-
Nguyen, A.; Top, S.; Pigeon, P.; Vessieres, A.; Hillard, E.A.; Plamont, M.A.; Huche, M.; Rigamonti, C., Jaouen, G. Synthesis and structure-activity relationships of ferrocenyl tamoxifen derivatives with modified side chains. Chemistry, 2009, 15, 684-696.
-
(2009)
Chemistry
, vol.15
, pp. 684-696
-
-
Nguyen, A.1
Top, S.2
Pigeon, P.3
Vessieres, A.4
Hillard, E.A.5
Plamont, M.A.6
Huche, M.7
Rigamonti, C.8
Jaouen, G.9
-
26
-
-
33846780995
-
Organometallic analogues of tamoxifen: Effect of the amino sidechain replacement by a carbonyl ferrocenyl moiety in hydroxytamoxifen
-
Nguyen, A.; Top, S.; Vessières, A.; Pigeon, P.; Huché, M.; Hillard, E.A.; Jaouen, G. Organometallic analogues of tamoxifen: Effect of the amino sidechain replacement by a carbonyl ferrocenyl moiety in hydroxytamoxifen. J. Organomet. Chem., 2007, 692, 1219-1225.
-
(2007)
J. Organomet. Chem
, vol.692
, pp. 1219-1225
-
-
Nguyen, A.1
Top, S.2
Vessières, A.3
Pigeon, P.4
Huché, M.5
Hillard, E.A.6
Jaouen, G.7
-
27
-
-
77956652851
-
SERMs: Progress and future perspectives
-
Pickar, J.H., MacNeil, T., Ohleth, K. SERMs: Progress and future perspectives. Maturitas, 2010, 67, 129-138.
-
(2010)
Maturitas
, vol.67
, pp. 129-138
-
-
Pickar, J.H.1
Macneil, T.2
Ohleth, K.3
-
28
-
-
79960842378
-
Toremifene is an effective and safe alternative to tamoxifen in adjuvant endocrine therapy for breast cancer: Results of four randomized trials
-
Zhou, W.B., Ding, Q., Chen, L., Liu, X.A., Wang, S. Toremifene is an effective and safe alternative to tamoxifen in adjuvant endocrine therapy for breast cancer: results of four randomized trials. Breast Cancer Res.Treat., 2011, 128, 625-631.
-
(2011)
Breast Cancer Res.Treat
, vol.128
, pp. 625-631
-
-
Zhou, W.B.1
Ding, Q.2
Chen, L.3
Liu, X.A.4
Wang, S.5
-
29
-
-
0030333304
-
Epidemiology of susceptibility to breast cancer
-
Hulka, B.S. Epidemiology of susceptibility to breast cancer. Prog. Clin. Biol. Res., 1996, 395, 159-174.
-
(1996)
Prog. Clin. Biol. Res
, vol.395
, pp. 159-174
-
-
Hulka, B.S.1
-
30
-
-
0036041129
-
Estrogen as therapy for breast cancer
-
Ingle, J.N. Estrogen as therapy for breast cancer. Breast Cancer Res., 2002, 4, 133-136.
-
(2002)
Breast Cancer Res
, vol.4
, pp. 133-136
-
-
Ingle, J.N.1
-
31
-
-
40649108301
-
Aromatase inhibitors in adjuvant therapy for hormone receptor positive breast cancer: A systematic review
-
Eisen, A.; Trudeau, M.; Shelley, W.; Messersmith, H.; Pritchard, K.I. Aromatase inhibitors in adjuvant therapy for hormone receptor positive breast cancer: a systematic review. Cancer Treat. Rev., 2008, 34, 157-174.
-
(2008)
Cancer Treat. Rev
, vol.34
, pp. 157-174
-
-
Eisen, A.1
Trudeau, M.2
Shelley, W.3
Messersmith, H.4
Pritchard, K.I.5
-
32
-
-
33749049776
-
Adjuvant trials: Aromatase inhibitors in early breast cancer-are they alike?
-
Monnier, A. Adjuvant trials: Aromatase inhibitors in early breast cancer-are they alike? Cancer Treat. Rev., 2006, 32, 532-540.
-
(2006)
Cancer Treat. Rev
, vol.32
, pp. 532-540
-
-
Monnier, A.1
-
33
-
-
33745249570
-
Effects of tamoxifen vs raloxifene on the risk of developing invasive breast cancer and other disease outcomes: The NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 trial
-
Vogel, V.G.; Costantino, J.P.; Wickerham, D.L.; Cronin, W.M.; Cecchini, R.S.; Atkins, J.N.; Bevers, T.B.; Fehrenbacher, L.; Pajon, E.R. Jr.; Wade, J.L., 3rd; Robidoux, A.; Margolese, R.G.; James, J.; Lippman, S.M.; Runowicz, C.D.; Ganz, P.A.; Reis, S.E.; McCaskill-Stevens, W.; Ford, L.G.; Jordan, V.C.; Wolmark, N. Effects of tamoxifen vs raloxifene on the risk of developing invasive breast cancer and other disease outcomes: the NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 trial. JAMA, 2006, 295, 2727-2741.
-
(2006)
JAMA
, vol.295
, pp. 2727-2741
-
-
Vogel, V.G.1
Costantino, J.P.2
Wickerham, D.L.3
Cronin, W.M.4
Cecchini, R.S.5
Atkins, J.N.6
Bevers, T.B.7
Fehrenbacher, L.8
Pajon Jr., E.R.9
Wade, J.L.10
Robidoux, A.11
Margolese, R.G.12
James, J.13
Lippman, S.M.14
Runowicz, C.D.15
Ganz, P.A.16
Reis, S.E.17
McCaskill-Stevens, W.18
Ford, L.G.19
Jordan, V.C.20
Wolmark, N.21
more..
-
34
-
-
36949059277
-
Contrasting endocrine activities of cis and trans isomers in a series of substituted triphenylethylenes
-
Harper, M.J.; Walpole, A.L. Contrasting endocrine activities of cis and trans isomers in a series of substituted triphenylethylenes. Nature, 1966, 212, 87.
-
(1966)
Nature
, vol.212
, pp. 87
-
-
Harper, M.J.1
Walpole, A.L.2
-
35
-
-
0020033521
-
Tamoxifen antiestrogens. A comparison of the activity, pharmacokinetics, and metabolic activation of the cis and trans isomers of tamoxifen
-
Robertson, D.W.; Katzenellenbogen, J.A.; Long, D.J.; Rorke, E.A.; Katzenellenbogen, B.S. Tamoxifen antiestrogens. A comparison of the activity, pharmacokinetics, and metabolic activation of the cis and trans isomers of tamoxifen. J. Steroid. Biochem., 1982, 16, 1-13.
-
(1982)
J. Steroid. Biochem
, vol.16
, pp. 1-13
-
-
Robertson, D.W.1
Katzenellenbogen, J.A.2
Long, D.J.3
Rorke, E.A.4
Katzenellenbogen, B.S.5
-
36
-
-
77952111172
-
Aconvenient synthesis of (Z)-4- hydroxy-N-desmethyltamoxifen (endoxifen)
-
Fauq, A.H., Maharvi, G.M., Sinha, D. A convenient synthesis of (Z)-4- hydroxy-N-desmethyltamoxifen (endoxifen). Bioorg. Med. Chem. Lett., 2010, 20, 3036-3038.
-
(2010)
Bioorg. Med. Chem. Lett
, vol.20
, pp. 3036-3038
-
-
Fauq, A.H.1
Maharvi, G.M.2
Sinha, D.3
-
37
-
-
77950028099
-
Endoxifen is a new potent inhibitor of PKC: A potential therapeutic agent for bipolar disorder
-
Ali, S.M., Ahmad, A., Shahabuddin, S., Ahmad, M.U., Sheikh, S., Ahmad, I. Endoxifen is a new potent inhibitor of PKC: A potential therapeutic agent for bipolar disorder. Bioorg. Med. Chem. Lett., 2010, 20, 2665-2667.
-
(2010)
Bioorg. Med. Chem. Lett
, vol.20
, pp. 2665-2667
-
-
Ali, S.M.1
Ahmad, A.2
Shahabuddin, S.3
Ahmad, M.U.4
Sheikh, S.5
Ahmad, I.6
-
38
-
-
85197346300
-
Estrogenic activity of some hydrocarbon derivatives of ethylene
-
Dodds, C.E.; Fitzgerald, M.E.H.; Lawson, W. Estrogenic activity of some hydrocarbon derivatives of ethylene. Nature, 1940, 140, 772.
-
(1940)
Nature
, vol.140
, pp. 772
-
-
Dodds, C.E.1
Fitzgerald, M.E.H.2
Lawson, W.3
-
39
-
-
85046393626
-
Oestrous reactions including mating produced by triphenylethylene
-
Robson, J.M.; Schönberg, A. Oestrous reactions including mating produced by triphenylethylene. Nature, 1937, 140, 196.
-
(1937)
Nature
, vol.140
, pp. 196
-
-
Robson, J.M.1
Schönberg, A.2
-
40
-
-
0001761072
-
Preparation and Identification of cis and trans Isomers of a Substituted Triarylethylene
-
Bedford, G.R.; Richardson, D.N. Preparation and Identification of cis and trans Isomers of a Substituted Triarylethylene. Nature, 1966, 212, 733-734.
-
(1966)
Nature
, vol.212
, pp. 733-734
-
-
Bedford, G.R.1
Richardson, D.N.2
-
41
-
-
0015136407
-
Antiestrogenic and antifertility compounds. 4. 1,1,2-Triarylalkan-1-ols and 1,1,2-Triarylalk-1-enes containing basic ether groups
-
Collins, D.J.; Hobbs, J.J.; Emmens, C.W. Antiestrogenic and antifertility compounds. 4. 1,1,2-Triarylalkan-1-ols and 1,1,2-Triarylalk-1-enes containing basic ether groups. J. Med. Chem., 1971, 14, 952-957.
-
(1971)
J. Med. Chem
, vol.14
, pp. 952-957
-
-
Collins, D.J.1
Hobbs, J.J.2
Emmens, C.W.3
-
42
-
-
0019913863
-
Synthesis of the E and Z isomers of the antiestrogen Tamoxifen and it's metabolite, 4-Hydroxytamoxifen
-
Robertson, D.W.; Katzenellenbogen, J.A. Synthesis of the E and Z isomers of the antiestrogen Tamoxifen and it's metabolite, 4-Hydroxytamoxifen. J. Org. Chem., 1982, 47, 2387-2393.
-
(1982)
J. Org. Chem
, vol.47
, pp. 2387-2393
-
-
Robertson, D.W.1
Katzenellenbogen, J.A.2
-
43
-
-
37049090273
-
Stereoselective Olefin formation from the dehydration of 1-Cp- (Alkoxyphenyl)-1,2,-diphenylbutan-1-ols: Application to the Synthesis of Tamoxifen
-
McCague, R. Stereoselective Olefin formation from the dehydration of 1-Cp- (Alkoxyphenyl)-1,2,-diphenylbutan-1-ols: Application to the Synthesis of Tamoxifen. J. Chem. Soc. Perkin Trans. 1 1987, 1011-1015.
-
(1987)
J. Chem. Soc. Perkin Trans
, vol.1
, pp. 1011-1015
-
-
McCague, R.1
-
44
-
-
24844452667
-
The use of octafluorotoluene and pentafluoropyridine in the synthesis of pure Z and E isomers of tamoxifen
-
Jarman, M.; McCague, R. The use of octafluorotoluene and pentafluoropyridine in the synthesis of pure Z and E isomers of tamoxifen. J. Chem. Res., 1985, (S) 116-117 (M) 1342-1388.
-
(1985)
J. Chem. Res
, vol.116-117
, pp. 1342-1388
-
-
Jarman, M.1
McCague, R.2
-
45
-
-
78650284820
-
The use of the perfluorotolyl protecting group in the synthesis of pure Z- and E-isomers of 4-hydroxytamoxifen
-
miniprint 771-793
-
McCague, R. The use of the perfluorotolyl protecting group in the synthesis of pure Z- and E-isomers of 4-hydroxytamoxifen. J. Chem. Res., 1986, 58-59 miniprint 771-793.
-
(1986)
J. Chem. Res
, pp. 58-59
-
-
McCague, R.1
-
46
-
-
0028788170
-
Synthesis of tamoxifen and 4-hydroxytamoxifen using super-base metalated propylbenzene
-
Olier-Reuchet, C.; Aitken, D.J.; Bucourt, R.; Husson, H.-P. Synthesis of tamoxifen and 4-hydroxytamoxifen using super-base metalated propylbenzene. Tet. Lett., 1995, 36, 8221-8224.
-
(1995)
Tet. Lett
, vol.36
, pp. 8221-8224
-
-
Olier-Reuchet, C.1
Aitken, D.J.2
Bucourt, R.3
Husson, H.-P.4
-
47
-
-
0346618937
-
Crossed coupling of functionalised ketones by low valent titanium (the McMurry reaction): A new stereoselective synthesis of tamoxifen
-
Coe, P.L.; Scriven, C.E. Crossed coupling of functionalised ketones by low valent titanium (the McMurry reaction): a new stereoselective synthesis of tamoxifen. J. Chem. Soc. Perkin Trans. 1, 1986, 475-477.
-
(1986)
J. Chem. Soc. Perkin Trans
, vol.1
, pp. 475-477
-
-
Coe, P.L.1
Scriven, C.E.2
-
48
-
-
0037189197
-
Synthesis of (Z)-4- hydroxytamoxifen and (Z)-2-[4-[1-(p-hydroxyphenyl)-2-phenyl]- 1butenyl]phenoxyacetic acid
-
Detsi, A.; Koufaki, M.; Calogeropoulou, T. Synthesis of (Z)-4- hydroxytamoxifen and (Z)-2-[4-[1-(p-hydroxyphenyl)-2-phenyl]- 1butenyl]phenoxyacetic acid. J. Org. Chem., 2002, 67, 4608-4611.
-
(2002)
J. Org. Chem
, vol.67
, pp. 4608-4611
-
-
Detsi, A.1
Koufaki, M.2
Calogeropoulou, T.3
-
49
-
-
0344391944
-
Simple and efficient production of (Z)-4- hydroxytamoxifen, a potent estrogen receptor modulator
-
Yu, D.D.; Forman, B.M. Simple and efficient production of (Z)-4- hydroxytamoxifen, a potent estrogen receptor modulator. J. Org. Chem., 2003, 68, 9489-9491.
-
(2003)
J. Org. Chem
, vol.68
, pp. 9489-9491
-
-
Yu, D.D.1
Forman, B.M.2
-
50
-
-
0021856564
-
Stereospecific synthesis of (z)-tamoxifen via carbometalation of alkynylsilane
-
and references therein
-
Miller, R.B.; Al-Hassan, M.J. Stereospecific synthesis of (z)-tamoxifen via carbometalation of alkynylsilane. J. Org. Chem., 1985, 50, 2121-2123. and references therein.
-
(1985)
J. Org. Chem
, vol.50
, pp. 2121-2123
-
-
Miller, R.B.1
Al-Hassan, M.J.2
-
51
-
-
33646799346
-
A highly stereoselective synthesis of 1-halo-1- (trimethylsilyl)-2,2-dialkyl olefins
-
and references therein
-
Miller, R.B.; Al-Hassan, M.J. A highly stereoselective synthesis of 1-halo-1- (trimethylsilyl)-2,2-dialkyl olefins. J. Org. Chem., 1984, 49, 725-726. and references therein.
-
(1984)
J. Org. Chem
, vol.49
, pp. 725-726
-
-
Miller, R.B.1
Al-Hassan, M.J.2
-
52
-
-
0141856130
-
Z)-tamoxifen and tetrasubstituted alkenes and dienes via a regio- and stereospecific threecomponent magnesium carbometalation palladium(0) cross-coupling strategy
-
Tessier, P.E.; Penwell, A.J.; Souza, F.E.; Fallis, A.G. (Z)-tamoxifen and tetrasubstituted alkenes and dienes via a regio- and stereospecific threecomponent magnesium carbometalation palladium(0) cross-coupling strategy. Org. Lett., 2003, 5, 2989-2992.
-
(2003)
Org. Lett
, vol.5
, pp. 2989-2992
-
-
Tessier, P.E.1
Penwell, A.J.2
Souza, F.E.3
Fallis, A.G.4
-
53
-
-
12744254235
-
Palladium-catalyzed double cross-coupling of Evinylic dibromides with PhZnCl and the synthesis of tamoxifen
-
Pilli, R.A.; Robello, L.G. Palladium-catalyzed double cross-coupling of Evinylic dibromides with PhZnCl and the synthesis of tamoxifen. J. Braz. Chem. Soc., 2004, 15, 938-944.
-
(2004)
J. Braz. Chem. Soc
, vol.15
, pp. 938-944
-
-
Pilli, R.A.1
Robello, L.G.2
-
54
-
-
0032510182
-
A nickel catalyzed carbozincation of aryl-substituted alkynes
-
Stüdemann, T.M.; Ibrahim-Ouali, M.; Knochel, P. A nickel catalyzed carbozincation of aryl-substituted alkynes. Tetrahedron, 1998, 54, 1299-1316.
-
(1998)
Tetrahedron
, vol.54
, pp. 1299-1316
-
-
Stüdemann, T.M.1
Ibrahim-Ouali, M.2
Knochel, P.3
-
55
-
-
0030739251
-
A nickel catalyzed carbozincation of alkynes: A short synthesis of (Z)-tamoxifen
-
Stüdemann, T.M.; Knochel, P. A nickel catalyzed carbozincation of alkynes: A short synthesis of (Z)-tamoxifen. Angew. Chem. Int. Ed. Engl., 1997, 36, 93-95.
-
(1997)
Angew. Chem. Int. Ed. Engl
, vol.36
, pp. 93-95
-
-
Stüdemann, T.M.1
Knochel, P.2
-
56
-
-
0001076464
-
Synthesis of cis- and trans-tamoxifen
-
Al-Hassan, M.J. Synthesis of cis- and trans-tamoxifen. Synth. Commun., 1987, 17, 1247-1251.
-
(1987)
Synth. Commun
, vol.17
, pp. 1247-1251
-
-
Al-Hassan, M.J.1
-
57
-
-
60949085957
-
Copper catalyzed synthesis of β-haloalkenyl chalcogenides by addition of dichalcogenides to internal alkynes and its application to synthesis of (Z)-tamoxifen
-
Tanigushi, N. Copper catalyzed synthesis of β-haloalkenyl chalcogenides by addition of dichalcogenides to internal alkynes and its application to synthesis of (Z)-tamoxifen. Tetrahedron, 2009, 65, 2782-2790.
-
(2009)
Tetrahedron
, vol.65
, pp. 2782-2790
-
-
Tanigushi, N.1
-
58
-
-
70449393366
-
Trans- Stilbene as a starting material for the synthesis of tamoxifen based on palladium- catalyzed cross-coupling reactions
-
Nunes, C.M.; Limberger, J.; Poersch, S.; Seferin, M.; Monteiro, A.L. Trans- Stilbene as a starting material for the synthesis of tamoxifen based on palladium- catalyzed cross-coupling reactions. Synthesis 2009, 16, 2761-2765.
-
(2009)
Synthesis
, vol.16
, pp. 2761-2765
-
-
Nunes, C.M.1
Limberger, J.2
Poersch, S.3
Seferin, M.4
Monteiro, A.L.5
-
59
-
-
0345293203
-
Diversity-oriented synthesis of tamoxifentype tetrasubstituted olefins
-
Itami, K.; Kamei, T., Yoshida, J. Diversity-oriented synthesis of tamoxifentype tetrasubstituted olefins. J. Am. Chem. Soc., 2003, 125, 14670-14671.
-
(2003)
J. Am. Chem. Soc
, vol.125
, pp. 14670-14671
-
-
Itami, K.1
Kamei, T.2
Yoshida, J.3
-
60
-
-
33751293643
-
Effective synthesis of tamoxifen using nickel-catalyzed arylative carboxylation
-
Shimizu, K.; Takimoto, M.; Mori, M., Sato, Y. Effective synthesis of tamoxifen using nickel-catalyzed arylative carboxylation. Synlett, 2006, 18, 3182-3184.
-
(2006)
Synlett
, vol.18
, pp. 3182-3184
-
-
Shimizu, K.1
Takimoto, M.2
Mori, M.3
Sato, Y.4
-
61
-
-
0029563081
-
Stereospecific synthesis of clomiphene and tamoxifen via stannylcupration of diphenylacetylene
-
Cummins, C.H. Stereospecific synthesis of clomiphene and tamoxifen via stannylcupration of diphenylacetylene. Synth. Commun., 1995, 25, 4071-4079
-
(1995)
Synth. Commun
, vol.25
, pp. 4071-4079
-
-
Cummins, C.H.1
-
62
-
-
0345761313
-
Short-step synthesis of tamoxifen and itsderivatives via the three-component coupling reaction and migration of the double bond
-
Shiina, I.; Suzuki, M., Yokoyama, K. Short-step synthesis of tamoxifen and itsderivatives via the three-component coupling reaction and migration of the double bond. Tet. Lett., 2004, 45, 965-967.
-
(2004)
Tet. Lett
, vol.45
, pp. 965-967
-
-
Shiina, I.1
Suzuki, M.2
Yokoyama, K.3
-
63
-
-
0015014820
-
Diethylstilbestrol cis-trans isomerization and estrogen activity of diethylstilbestrol isomers
-
Winkler, V.W.; Nyman, M.A., Egan, R.S. Diethylstilbestrol cis-trans isomerization and estrogen activity of diethylstilbestrol isomers. Steroids, 1971, 17, 197-207.
-
(1971)
Steroids
, vol.17
, pp. 197-207
-
-
Winkler, V.W.1
Nyman, M.A.2
Egan, R.S.3
-
64
-
-
35348816924
-
An expeditious synthesis of tamoxifen, a representative SERM (selective estrogen receptor modulator), via the three-component coupling reaction among aromatic aldehyde, cinnamyltrimethylsilane, and beta-chlorophenetole
-
Shiina, I.; Sano, Y.; Nakata, K.; Suzuki, M.; Yokoyama, T.; Sasaki, A.; Orikasa, T.; Miyamoto, T.; Ikekita, M.; Nagahara, Y.; Hasome, Y. An expeditious synthesis of tamoxifen, a representative SERM (selective estrogen receptor modulator), via the three-component coupling reaction among aromatic aldehyde, cinnamyltrimethylsilane, and beta-chlorophenetole. Bioorg. Med. Chem., 2007, 15, 7599-7617.
-
(2007)
Bioorg. Med. Chem
, vol.15
, pp. 7599-7617
-
-
Shiina, I.1
Sano, Y.2
Nakata, K.3
Suzuki, M.4
Yokoyama, T.5
Sasaki, A.6
Orikasa, T.7
Miyamoto, T.8
Ikekita, M.9
Nagahara, Y.10
Hasome, Y.11
-
65
-
-
0037471514
-
Preparation of β, n-dilithiotoluene equivalents. Synthesis of tamoxifen
-
Yus, M.; Ramón, D.J.; Gómez, I. Preparation of β, n-dilithiotoluene equivalents. Synthesis of tamoxifen. Tetrahedron, 2003, 59, 3219-3225.
-
(2003)
Tetrahedron
, vol.59
, pp. 3219-3225
-
-
Yus, M.1
Ramón, D.J.2
Gómez, I.3
-
66
-
-
29144514460
-
Wittig-Horner approach for the synthesis of tamoxifen
-
Pandey, R.K.; Wakharkar, R.D.; Kumar, P. Wittig-Horner approach for the synthesis of tamoxifen. Synth. Commun., 2005, 35, 2795-2800.
-
(2005)
Synth. Commun
, vol.35
, pp. 2795-2800
-
-
Pandey, R.K.1
Wakharkar, R.D.2
Kumar, P.3
-
67
-
-
0030831922
-
Parallel synthesis of tamoxifen and derivatives on solid support via resin capture
-
Brown, D.S.; Armstrong, R.W. Parallel synthesis of tamoxifen and derivatives on solid support via resin capture. J. Org. Chem., 1997, 62, 7076-7077.
-
(1997)
J. Org. Chem
, vol.62
, pp. 7076-7077
-
-
Brown, D.S.1
Armstrong, R.W.2
|