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Volumn 125, Issue 48, 2003, Pages 14670-14671

Diversity-Oriented Synthesis of Tamoxifen-type Tetrasubstituted Olefins

Author keywords

[No Author keywords available]

Indexed keywords

ALKENE DERIVATIVE; CARBON; COPPER; IODINE; PALLADIUM; PYRIDINE DERIVATIVE; SILANE DERIVATIVE; SILICON; TAMOXIFEN DERIVATIVE;

EID: 0345293203     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja037566i     Document Type: Article
Times cited : (203)

References (36)
  • 7
    • 36949059277 scopus 로고
    • While the Z-isomer of tamoxifen is antiestrogenic, the E-isomer is an estrogen agonist. Harper, M. J.; Walpole, A. L. Nature 1966, 212, 87.
    • (1966) Nature , vol.212 , pp. 87
    • Harper, M.J.1    Walpole, A.L.2
  • 14
    • 0034595320 scopus 로고    scopus 로고
    • Selected recent examples of removable directing group strategy: (a) Breit, B. Chem.-Eur. J. 2000, 6, 1519.
    • (2000) Chem.-Eur. J. , vol.6 , pp. 1519
    • Breit, B.1
  • 25
    • 0344113584 scopus 로고    scopus 로고
    • Reference 6a
    • (d) Reference 6a.
  • 26
    • 0035833014 scopus 로고    scopus 로고
    • For a review on directed alkyne carbometalation, see: Fallis, A. G.; Forgione, P. Tetrahedron 2001, 57, 5899.
    • (2001) Tetrahedron , vol.57 , pp. 5899
    • Fallis, A.G.1    Forgione, P.2
  • 27
    • 0034600318 scopus 로고    scopus 로고
    • 3 is an excellent catalyst for Suzuki-Miyaura, Negishi, and Migita-Kosugi-Stille cross-coupling reactions. (a) Littke, A. F.; Dai, C.; Fu, G. C. J. Am. Chem. Soc. 2000, 122, 4020.
    • (2000) J. Am. Chem. Soc. , vol.122 , pp. 4020
    • Littke, A.F.1    Dai, C.2    Fu, G.C.3
  • 33
    • 0344113583 scopus 로고    scopus 로고
    • note
    • When the cross-coupling step was performed at room temperature, 3 could be obtained in higher stereoselectivity (usually greater than 99%) at the expense of a lower chemical yield (30-50%).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.