Simple and Efficient Production of (Z)-4-Hydroxytamoxifen, a Potent Estrogen Receptor Modulator

Journal of Organic Chemistry

Volumn 68, Issue 24, 2003, Pages 9489-9491

  Yu, Donna D ^a   Forman, Barry M ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COUPLING REACTIONS;

CRYSTALLIZATION; HORMONES; METABOLITES; PROTEINS; TUMORS;

AROMATIC COMPOUNDS;

1,1 BIS(4 HYDROXYPHENYL) 2 PHENYLBUT 1 ENE; 4 HYDROXYTAMOXIFEN; ALKENE DERIVATIVE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; TAMOXIFEN; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CRYSTALLIZATION; DRUG SYNTHESIS; FRIEDEL CRAFTS REACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PROTON NUCLEAR MAGNETIC RESONANCE; THIN LAYER CHROMATOGRAPHY;

BINDING, COMPETITIVE; CRYSTALLIZATION; ESTRADIOL; MODELS, CHEMICAL; MOLECULAR STRUCTURE; SELECTIVE ESTROGEN RECEPTOR MODULATORS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TAMOXIFEN;

EID: 0344391944     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo035164n     Document Type: Article

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