High affinity 17α-substituted estradiol derivatives: Synthesis and evaluation of estrogen receptor agonist activity

Steroids

Volumn 71, Issue 3, 2006, Pages 249-255

  Kasiotis, Konstantinos M ^a   Mendorou, Christina ^b   Haroutounian, Serkos A ^a   Alexis, Michael N ^b  

^a AGRICULTURAL UNIVERSITY OF ATHENS   (Greece)

^b INSTITUTE OF BIOLOGY   (Greece)

Author keywords

17 Alkynylazido estradiol derivatives; Estrogenic activity

Indexed keywords

17ALPHA (5 AZIDO PENT 1 YNYL) 3,17BETA ESTRADIOL; 17ALPHA (AZIDOPENTYN 2 YL) 3,17BETA ESTRADIOL; 17ALPHA (AZIDOPROPARGYL) 3,17BETA ESTRADIOL; 17ALPHA 17 (3 AZIDO PROP 1 YNYL) 13 METHYL 7,8,9,11,12,13,14,15,16,17 DECAHYDRO 6H CYCLOPENTA[A]PHENANTHREN 3 OL; 17ALPHA ESTRADIOL; ALKALINE PHOSPHATASE; ANTIESTROGEN; AZIDE; ESTRADIOL DERIVATIVE; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; HORMONE RECEPTOR STIMULATING AGENT; LUCIFERASE; UNCLASSIFIED DRUG; DRUG DERIVATIVE; ESTRADIOL;

ARTICLE; BINDING AFFINITY; BREAST CANCER; CANCER CELL; CELL CLONE; CELL LINE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; ENDOMETRIUM CANCER; ENZYME INDUCTION; ESTROGEN ACTIVITY; GENE EXPRESSION; GENETIC TRANSFECTION; HORMONE RESPONSE; HUMAN; HUMAN CELL; PHOTOAFFINITY LABELING; BREAST TUMOR; CELL CULTURE; DRUG POTENTIATION; ENDOMETRIUM TUMOR; EVALUATION; FEMALE; METABOLISM; PATHOLOGY; PROTEIN BINDING; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

MINK CELL FOCUS-FORMING VIRUS;

ALKALINE PHOSPHATASE; BREAST NEOPLASMS; ENDOMETRIAL NEOPLASMS; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FEMALE; HUMANS; LUCIFERASES; PROTEIN BINDING; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 32144447789     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2005.10.004     Document Type: Article

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