p38 MAPK inhibition suppresses the TLR-hypersensitive phenotype in FANCC and FANCA-deficient mononuclear phagocytes

Blood

Volumn 119, Issue 9, 2012, Pages 1992-2002

  Anur, Praveen ^a,b,c   Yates, Jane ^a   Garbati, Michael R ^a   Vanderwerf, Scott ^b   Keeble, Winifred ^a,b   Rathbun, Keaney ^a   Hays, Laura E ^a,b   Tyner, Jeffrey W ^a   Svahn, Johanna ^d   Cappelli, Enrico ^d   Dufour, Carlo ^d   Bagby, Grover C ^a,b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b Northwest Veterans Affairs Cancer Research Center   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^d G GASLINI INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DASATINIB; DORAMAPIMOD; FANCONI ANEMIA GROUP A PROTEIN; FANCONI ANEMIA GROUP C PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME INHIBITION; FANCONI ANEMIA; GENE EXPRESSION; GENETIC TRANSCRIPTION; HEMATOPOIETIC CELL; MOLECULE; MONONUCLEAR PHAGOCYTE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REPORTER GENE;

EID: 84857738200     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-06-354647     Document Type: Article

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