Delayed inhibition of angiotensin II receptor type 1 reduces secondary brain damage and improves functional recovery after experimental brain trauma*

Critical Care Medicine

Volumn 40, Issue 3, 2012, Pages 935-944

  Timaru Kast, Ralph ^a   Wyschkon, Sebastian ^a   Luh, Clara ^a   Schaible, Eva Verena ^a   Lehmann, Florian ^a   Merk, Philipp ^a   Werner, Christian ^a   Engelhard, Kristin ^a   Thal, Serge C ^a  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

angiotensin; angiotensin II receptor type 1; AT1; AT1 inhibition; brain trauma; controlled cortical impact; mice; renin angiotensin system; traumatic brain injury

Indexed keywords

ANGIOTENSIN RECEPTOR; ANGIOTENSIN RECEPTOR 1A; ANGIOTENSIN RECEPTOR 1B; CANDESARTAN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE REGULATION; BRAIN DAMAGE; BRAIN EDEMA; BRAIN SIZE; CONTROLLED STUDY; CONVALESCENCE; DOSE RESPONSE; ENCEPHALITIS; GENE EXPRESSION; MALE; MICROGLIA; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; TRAUMATIC BRAIN INJURY; WATER CONTENT;

ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; BRAIN INJURIES; MALE; MICE; MICE, INBRED C57BL; RECOVERY OF FUNCTION; RENIN-ANGIOTENSIN SYSTEM;

EID: 84857641407     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e31822f08b9     Document Type: Article

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