Blockade of AT1 receptors protects the blood-brain barrier and improves cognition in dahl salt-sensitive hypertensive rats

American Journal of Hypertension

Volumn 24, Issue 3, 2011, Pages 362-368

  Pelisch, Nicolas ^a   Hosomi, Naohisa ^b   Ueno, Masaki ^a   Nakano, Daisuke ^a   Hitomi, Hirofumi ^a   Mogi, Masaki ^c   Shimada, Kenji ^d   Kobori, Hiroyuki ^e   Horiuchi, Masatsugu ^c   Sakamoto, Haruhiko ^a   Matsumoto, Masayasu ^b   Kohno, Masakazu ^a   Nishiyama, Akira ^a  

^a KAGAWA UNIVERSITY   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

^c EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d UNIVERSITY OF TOKUSHIMA   (Japan)

^e TULANE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

blood pressure; blood brain barrier; cognitive impairment; hypertension; receptors; vascular cognitive impairment

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; COLLAGEN TYPE 4; MESSENGER RNA; OLMESARTAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BLOOD PRESSURE REGULATION; BRAIN; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DAHL SALT SENSITIVE RAT; HIPPOCAMPUS; HYPERTENSION; MALE; MICROVASCULATURE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SODIUM RESTRICTION; TIGHT JUNCTION;

ANGIOTENSIN II; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; ANTIGENS, CD31; BLOOD-BRAIN BARRIER; BODY WEIGHT; CAPILLARY PERMEABILITY; COGNITION; CORPUS CALLOSUM; HIPPOCAMPUS; HYPERTENSION; IMIDAZOLES; IMMUNOHISTOCHEMISTRY; MALE; RATS; RATS, INBRED DAHL; RNA, MESSENGER; SYSTOLE; TETRAZOLES;

EID: 79951677532     PISSN: 08957061     EISSN: None     Source Type: Journal    
DOI: 10.1038/ajh.2010.241     Document Type: Article

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