Inhibition of myosin light chain kinase reduces brain edema formation after traumatic brain injury

Journal of Neurochemistry

Volumn 112, Issue 4, 2010, Pages 1015-1025

  Luh, Clara ^a   Kuhlmann, Christoph R ^a   Ackermann, Bianca ^a   Timaru Kast, Ralph ^a   Luhmann, Heiko J ^a   Behl, Christian ^a   Werner, Christian ^a   Engelhard, Kristin ^a   Thal, Serge C ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Brain edema; MLCK; Myosin light chain; Phosphorylation; PMLC; Traumatic brain injury

Indexed keywords

1 (5 IODO 1 NAPHTHALENESULFONYL)HEXAHYDRO 1H 1,4 DIAZEPINE; MYOSIN LIGHT CHAIN; MYOSIN LIGHT CHAIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN DAMAGE; BRAIN EDEMA; BRAIN FUNCTION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; INTRACRANIAL HYPERTENSION; MALE; MOUSE; NEUROPATHOLOGY; NEUROPROTECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TRAUMATIC BRAIN INJURY; TREATMENT OUTCOME; UPREGULATION;

ANIMALS; AZEPINES; BLOOD-BRAIN BARRIER; BRAIN EDEMA; BRAIN INJURIES; CONSTRICTION; DISEASE MODELS, ANIMAL; DRUG ADMINISTRATION SCHEDULE; ENZYME INHIBITORS; EVANS BLUE; FUNCTIONAL LATERALITY; GENE EXPRESSION REGULATION; INTRACRANIAL PRESSURE; MALE; MICE; MICE, INBRED C57BL; MYOSIN LIGHT CHAINS; MYOSIN-LIGHT-CHAIN KINASE; NAPHTHALENES; NEUROLOGIC EXAMINATION; STATISTICS, NONPARAMETRIC; TIME FACTORS;

MUS;

EID: 75149195436     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06514.x     Document Type: Article

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