Systemic candesartan reduces brain angiotensin II via downregulation of brain renin-angiotensin system

Hypertension Research

Volumn 33, Issue 2, 2010, Pages 161-164

  Pelisch, Nicolas ^a   Hosomi, Naohisa ^a   Ueno, Masaki ^a   Masugata, Hisashi ^a   Murao, Koji ^a   Hitomi, Hirofumi ^a   Nakano, Daisuke ^a   Kobori, Hiroyuki ^b   Nishiyama, Akira ^a   Kohno, Masakazu ^a  

^a KAGAWA UNIVERSITY   (Japan)

^b TULANE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

Angiotensin II; AT1 type 1 receptor; Brain; Candesartan

Indexed keywords

ANGIOTENSIN II; ANGIOTENSINOGEN; CANDESARTAN; DIPEPTIDYL CARBOXYPEPTIDASE;

ANGIOTENSIN II BRAIN LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASAL GANGLION; BLOOD BRAIN BARRIER; BRAIN LEVEL; BRAIN TISSUE; CONTROLLED STUDY; DOWN REGULATION; DRUG BLOOD LEVEL; DRUG MECHANISM; DRUG PENETRATION; GENE EXPRESSION; MALE; NONHUMAN; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SPRAGUE DAWLEY RAT; SYSTOLIC BLOOD PRESSURE;

ANGIOTENSIN II; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; BENZIMIDAZOLES; BLOOD PRESSURE; BLOOD-BRAIN BARRIER; BODY WEIGHT; BRAIN CHEMISTRY; DOWN-REGULATION; MALE; PERMEABILITY; RATS; RATS, SPRAGUE-DAWLEY; RENIN-ANGIOTENSIN SYSTEM; TETRAZOLES;

EID: 76349103242     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1038/hr.2009.200     Document Type: Article

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