Update on biologic pathways in inflammatory bowel disease and their therapeutic relevance

Journal of Gastroenterology

Volumn 47, Issue 1, 2012, Pages 1-8

  Hamilton, Matthew J ^a   Snapper, Scott B ^a,b   Blumberg, Richard S ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Autophagy; Bacterial sensing; Crohn's disease; Inflammatory bowel disease; Intestinal homeostasis; Ulcerative colitis

Indexed keywords

ALPHA DEFENSIN; CASPASE RECRUITMENT DOMAIN PROTEIN 15; CHEMOKINE RECEPTOR CCR6; CRYOPYRIN; G COUPLED RECEPTOR 43; INFLAMMASOME; INTEGRIN; INTEGRIN ALPHA4BETA7; INTERLEUKIN 12; INTERLEUKIN 12P40; INTERLEUKIN 13; INTERLEUKIN 1BETA; INTERLEUKIN 23; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MONOCLONAL ANTIBODY; NATALIZUMAB; NLRP6 PROTEIN; PLACEBO; PROTEIN; SHORT CHAIN FATTY ACID; TEKINUMAB; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR LIGAND RELATED MOLECULE 1A; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

APOPTOSIS; ATG16L1 GENE; AUTOPHAGY; CHRONIC INFLAMMATION; COMMENSAL; COMMENSAL BACTERIA; CROHN DISEASE; CYTOKINE PRODUCTION; ENDOPLASMIC RETICULUM STRESS; ENTERITIS; GENE; GENE MUTATION; HOMEOSTASIS; HOST PATHOGEN INTERACTION; HUMAN; INTESTINE EPITHELIUM CELL; INTESTINE FLORA; LAMINA PROPRIA; LYMPHOCYTE HOMING; LYMPHOCYTE RECIRCULATION; MULTIPLE SCLEROSIS; NATURAL KILLER CELL MEDIATED CYTOTOXICITY; NATURAL KILLER T CELL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; POLYOMAVIRUS INFECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSORIASIS; REVIEW; TH17 CELL; TNFSF15 GENE; ULCERATIVE COLITIS; UNFOLDED PROTEIN RESPONSE; XBP1 GENE;

ANIMALS; AUTOPHAGY; CROHN DISEASE; GASTROINTESTINAL AGENTS; HUMANS; INFLAMMATORY BOWEL DISEASES; INTERLEUKIN-12; INTERLEUKIN-23; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84857634516     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-011-0521-8     Document Type: Review

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