Pseudomonas aeruginosa pyocyanin causes airway goblet cell hyperplasia and metaplasia and mucus hypersecretion by inactivating the transcriptional factor FoxA2

Cellular Microbiology

Volumn 14, Issue 3, 2012, Pages 401-415

  Hao, Yonghua ^a   Kuang, Zhizhou ^a   Walling, Brent E ^a   Bhatia, Shikha ^a   Sivaguru, Mayandi ^a   Chen, Yin ^b   Gaskins, H Rex ^a   Lau, Gee W ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; HEPATOCYTE NUCLEAR FACTOR 3BETA; INTERLEUKIN 13; INTERLEUKIN 4; KAEMPFEROL; MUCIN 5B; PYOCYANINE; RECOMBINANT INTERLEUKIN 13; STAT6 PROTEIN;

ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; BRONCHIECTASIS; CELL CULTURE; CELL HYPERPLASIA; CELL POPULATION; CELL TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DENSITOMETRY; DISEASE EXACERBATION; DOWN REGULATION; EMPHYSEMA; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; GOBLET CELL; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LUNG ALVEOLUS CELL; LUNG ALVEOLUS EPITHELIUM; LUNG FIBROSIS; METAPLASIA; MOUSE; MUCUS SECRETION; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSEUDOMONAS AERUGINOSA; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; CELL LINE, TUMOR; DOWN-REGULATION; GOBLET CELLS; HEPATOCYTE NUCLEAR FACTOR 3-BETA; HOST-PATHOGEN INTERACTIONS; HUMANS; HYPERPLASIA; LUNG; METAPLASIA; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUCIN-5B; MUCUS; PSEUDOMONAS AERUGINOSA; PYOCYANINE; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; STAT6 TRANSCRIPTION FACTOR; TRANSCRIPTIONAL ACTIVATION;

MUS; PSEUDOMONAS AERUGINOSA;

EID: 84857444102     PISSN: 14625814     EISSN: 14625822     Source Type: Journal    
DOI: 10.1111/j.1462-5822.2011.01727.x     Document Type: Article

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