Pseudomonas aeruginosa biofilm infections in cystic fibrosis: Insights into pathogenic processes and treatment strategies

Expert Opinion on Therapeutic Targets

Volumn 14, Issue 2, 2010, Pages 117-130

  Hassett, Daniel J ^a   Korfhagen, Thomas R ^a,b   Irvin, Randall T ^a,c   Schurr, Michael J ^a,d   Sauer, Karin ^a,e   Lau, Gee W ^a,f   Sutton, Mark D ^a,g   Yu, Hongwei ^a,h   Hoiby, Niels ^a,i  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^c UNIVERSITY OF ALBERTA   (Canada)

^d University of Colrado   (United States)

^e UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^f BINGHAMTON UNIVERSITY   (United States)

^g UNIVERSITY AT BUFFALO   (United States)

^h MARSHALL UNIVERSITY   (United States)

ⁱ UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Alginate; Alternative treatment strategies; Biofilms; Cystic fibrosis; Dispersion; Pseudomonas aeruginosa

Indexed keywords

ACETYLCYSTEINE; AMIKACIN; ANTIINFLAMMATORY AGENT; ARIKACE; BIIL 284; CEFTAZIDIME; CIPROFLOXACIN; DORNASE ALFA; FLAGELLIN; FOSFOMYCIN; GS 9310 11; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KB 001; LEUKOTRIENE RECEPTOR BLOCKING AGENT; LEVOFLOXACIN; MONOCLONAL ANTIBODY; MP 376; PROBIOTIC AGENT; PROTEINASE INHIBITOR; RECOMBINANT INTERLEUKIN 10; SODIUM NITRITE; TICARCILLIN; TOBRAMYCIN; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TUMOR NECROSIS FACTOR RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

ANAEROBIC METABOLISM; ANTIINFLAMMATORY ACTIVITY; BACTERIAL COLONIZATION; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERICIDAL ACTIVITY; BACTERIOPHAGE; BIOFILM; CATABOLISM; CELL COMMUNICATION; CLINICAL TRIAL; DISEASE EXACERBATION; DISEASE PREDISPOSITION; DNA DAMAGE; DNA REPAIR; DRUG MEGADOSE; EPITHELIUM CELL; FLAGELLUM; GENE MUTATION; GRANULOCYTE FUNCTION; HOST RESISTANCE; HUMAN; LUNG FIBROSIS; LUNG INJURY; MACROPHAGE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PERSISTENT INFECTION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS PNEUMONIA; QUORUM SENSING; RESPIRATORY EPITHELIUM; REVIEW; SIGNAL TRANSDUCTION; TISSUE INJURY;

BIOFILMS; CYSTIC FIBROSIS; FIMBRIAE, BACTERIAL; FLAGELLA; HUMANS; LUNG; NEUTROPHILS; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; QUORUM SENSING; SODIUM NITRITE;

EID: 74949103972     PISSN: 14728222     EISSN: None     Source Type: Journal    
DOI: 10.1517/14728220903454988     Document Type: Review

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