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Volumn 175, Issue 6, 2009, Pages 2473-2488

Pseudomonas aeruginosa exotoxin pyocyanin causes cystic fibrosis airway pathogenesis

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYPROLINE; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4; MUCIN 5AC; PSEUDOMONAS EXOTOXIN; PYOCYANINE; STAT6 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 73549097081     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2009.090166     Document Type: Article
Times cited : (140)

References (74)
  • 1
    • 0037027912 scopus 로고    scopus 로고
    • An overview of the pathogenesis of cystic fibrosis lung disease
    • Boucher RC: An overview of the pathogenesis of cystic fibrosis lung disease. Adv Drug Deliv Rev 2002, 54:1359-1371
    • (2002) Adv Drug Deliv Rev , vol.54 , pp. 1359-1371
    • Boucher, R.C.1
  • 3
    • 9644257146 scopus 로고    scopus 로고
    • The role of pyocyanin in Pseudomonas aeruginosa infection
    • Lau GW, Ran H, Hassett DJ, Kong FS: The role of pyocyanin in Pseudomonas aeruginosa infection. Trends Mol Med 2004, 10:599-606
    • (2004) Trends Mol Med , vol.10 , pp. 599-606
    • Lau, G.W.1    Ran, H.2    Hassett, D.J.3    Kong, F.S.4
  • 4
    • 23044512239 scopus 로고    scopus 로고
    • Modulation of lung epithelial functions by Pseudomonas aeruginosa
    • Lau GW, Hassett DJ, Britigan BE: Modulation of lung epithelial functions by Pseudomonas aeruginosa. Trends Microbiol 2005, 13:389-397
    • (2005) Trends Microbiol , vol.13 , pp. 389-397
    • Lau, G.W.1    Hassett, D.J.2    Britigan, B.E.3
  • 5
    • 0023777725 scopus 로고
    • Measurement of Pseudomonas aeruginosa phenazine pigments in sputum and assessment of their contribution to sputum sol toxicity for respiratory epithelium
    • Wilson RD, Sykes A, Watson D, Rutman A, Taylor GW, Cole PJ: Measurement of Pseudomonas aeruginosa phenazine pigments in sputum and assessment of their contribution to sputum sol toxicity for respiratory epithelium. Infect Immun 1988, 56:2515-2517
    • (1988) Infect Immun , vol.56 , pp. 2515-2517
    • Wilson, R.D.1    Sykes, A.2    Watson, D.3    Rutman, A.4    Taylor, G.W.5    Cole, P.J.6
  • 6
    • 0026675713 scopus 로고
    • Effect of pyocyanine, a pigment of Pseudomonas aeruginosa, on production of reactive nitrogen intermediates by murine alveolar macrophages
    • Shellito J, Nelson S, Sorensen RU: Effect of pyocyanine, a pigment of Pseudomonas aeruginosa, on production of reactive nitrogen intermediates by murine alveolar macrophages. Infect Immun 1992, 60:3913-3915
    • (1992) Infect Immun , vol.60 , pp. 3913-3915
    • Shellito, J.1    Nelson, S.2    Sorensen, R.U.3
  • 7
    • 0028841257 scopus 로고
    • Pyocyanin from Pseudomonas aeruginosa inhibits prostacyclin release from endothelial cells
    • Kamath J, Britigan BE, Cox C, Shasby M: Pyocyanin from Pseudomonas aeruginosa inhibits prostacyclin release from endothelial cells. Infect Immun 1995, 63:4921-4923
    • (1995) Infect Immun , vol.63 , pp. 4921-4923
    • Kamath, J.1    Britigan, B.E.2    Cox, C.3    Shasby, M.4
  • 8
    • 0026611252 scopus 로고
    • Leukotriene B4 omega-oxidation by human polymorphonuclear leukocytes is inhibited by pyocyanin, a phenazine derivative produced by Pseudomonas aeruginosa
    • Muller M, Sorrell TC: Leukotriene B4 omega-oxidation by human polymorphonuclear leukocytes is inhibited by pyocyanin, a phenazine derivative produced by Pseudomonas aeruginosa. Infect Immun 1992, 60:2536-2540
    • (1992) Infect Immun , vol.60 , pp. 2536-2540
    • Muller, M.1    Sorrell, T.C.2
  • 9
    • 0028715763 scopus 로고
    • Inhibition of platelet eicosanoid metabolism by the bacterial phenazine derivative pyocyanin
    • Muller M, Sztelma K, Sorrell T: Inhibition of platelet eicosanoid metabolism by the bacterial phenazine derivative pyocyanin. Ann NY Acad Sci 1994, 744:320-322
    • (1994) Ann NY Acad Sci , vol.744 , pp. 320-322
    • Muller, M.1    Sztelma, K.2    Sorrell, T.3
  • 10
    • 0030914805 scopus 로고    scopus 로고
    • Modulation of neutrophil superoxide response and intracellular diacylglyceride levels by the bacterial pigment pyocyanin
    • Muller M, Sorrell TC: Modulation of neutrophil superoxide response and intracellular diacylglyceride levels by the bacterial pigment pyocyanin. Infect Immun 1997, 65:2483-2487
    • (1997) Infect Immun , vol.65 , pp. 2483-2487
    • Muller, M.1    Sorrell, T.C.2
  • 11
    • 0037083467 scopus 로고    scopus 로고
    • Induction of neutrophil apoptosis by the Pseudomonas aeruginosa exotoxin pyocyanin: A potential mechanism of persistent infection
    • Usher L, Lawson R, Geary I, Taylor C, Bingle C, Taylor G, Whyte M: Induction of neutrophil apoptosis by the Pseudomonas aeruginosa exotoxin pyocyanin: a potential mechanism of persistent infection. J Immunol 2002, 168:1861-1868
    • (2002) J Immunol , vol.168 , pp. 1861-1868
    • Usher, L.1    Lawson, R.2    Geary, I.3    Taylor, C.4    Bingle, C.5    Taylor, G.6    Whyte, M.7
  • 12
    • 14844363440 scopus 로고    scopus 로고
    • Pyocyanin production by Pseudomonas aeruginosa induces neutrophil apoptosis and impairs neutrophil-mediated host defenses in vivo
    • Allen L, Dockrell DH, Pattery T, Lee DG, Cornelis P, Hellewell PG, Whyte MK: Pyocyanin production by Pseudomonas aeruginosa induces neutrophil apoptosis and impairs neutrophil-mediated host defenses in vivo. J Immunol 2005, 174:3643-3649
    • (2005) J Immunol , vol.174 , pp. 3643-3649
    • Allen, L.1    Dockrell, D.H.2    Pattery, T.3    Lee, D.G.4    Cornelis, P.5    Hellewell, P.G.6    Whyte, M.K.7
  • 13
    • 0033008431 scopus 로고    scopus 로고
    • The Pseudomonas aeruginosa secretory product pyocyanin inactivates alpha1 protease inhibitor: Implications for the pathogenesis of cystic fibrosis lung disease
    • Britigan B, Railsback M, Cox C: The Pseudomonas aeruginosa secretory product pyocyanin inactivates alpha1 protease inhibitor: implications for the pathogenesis of cystic fibrosis lung disease. Infect Immun 1999, 67:1207-1212
    • (1999) Infect Immun , vol.67 , pp. 1207-1212
    • Britigan, B.1    Railsback, M.2    Cox, C.3
  • 15
    • 0031792843 scopus 로고    scopus 로고
    • Pseudomonas pyocyanin increases interleukin-8 expression by human airway epithelial cells
    • Denning G, Wollenweber L, Railsback M, Cox C, Stoll L, Britigan B: Pseudomonas pyocyanin increases interleukin-8 expression by human airway epithelial cells. Infect Immun 1998, 66:5777-5784
    • (1998) Infect Immun , vol.66 , pp. 5777-5784
    • Denning, G.1    Wollenweber, L.2    Railsback, M.3    Cox, C.4    Stoll, L.5    Britigan, B.6
  • 16
    • 0042510716 scopus 로고    scopus 로고
    • Phenazine-1-carboxylic acid, a secondary metabolite of Pseudomonas aeruginosa, alters expression of immunomodulatory proteins by human airway epithelial cells
    • Denning GM, Iyer SS, Reszka KJ, O'Malley Y, Rasmussen GT, Britigan BE: Phenazine-1-carboxylic acid, a secondary metabolite of Pseudomonas aeruginosa, alters expression of immunomodulatory proteins by human airway epithelial cells. Am J Physiol Lung Cell Mol Physiol 2003, 285:L584-L592
    • (2003) Am J Physiol Lung Cell Mol Physiol , vol.285
    • Denning, G.M.1    Iyer, S.S.2    Reszka, K.J.3    O'Malley, Y.4    Rasmussen, G.T.5    Britigan, B.E.6
  • 17
    • 24744444302 scopus 로고    scopus 로고
    • Pyocyanin and its precursor phenazine-1-carboxylic acid increase IL-8 and intercellular adhesion molecule-1 expression in human airway epithelial cells by oxidant-dependent mechanisms
    • Look DC, Stoll LL, Romig SA, Humlicek A, Britigan BE, Denning GM: Pyocyanin and its precursor phenazine-1-carboxylic acid increase IL-8 and intercellular adhesion molecule-1 expression in human airway epithelial cells by oxidant-dependent mechanisms. J Immunol 2005, 175:4017-4023
    • (2005) J Immunol , vol.175 , pp. 4017-4023
    • Look, D.C.1    Stoll, L.L.2    Romig, S.A.3    Humlicek, A.4    Britigan, B.E.5    Denning, G.M.6
  • 18
    • 0023180559 scopus 로고
    • Studies on the mechanism of T cell inhibition by the Pseudomonas aeruginosa phenazine pigment pyocyanine
    • Nutman J, Berger M, Chase P, Dearborn D, Miller KM, Waller RL, Sorensen RU: Studies on the mechanism of T cell inhibition by the Pseudomonas aeruginosa phenazine pigment pyocyanine. J Immunol 1987, 138:3481-3487
    • (1987) J Immunol , vol.138 , pp. 3481-3487
    • Nutman, J.1    Berger, M.2    Chase, P.3    Dearborn, D.4    Miller, K.M.5    Waller, R.L.6    Sorensen, R.U.7
  • 20
    • 44949284249 scopus 로고
    • Effect of Pseudomonas aeruginosa-derived pyocyanin and 1-hydroxyphenazine on pulmonary mucociliary clearance monitored scintigraphically in the baboon model
    • Dormehl I, Ras G, Taylor G, Hugo N: Effect of Pseudomonas aeruginosa-derived pyocyanin and 1-hydroxyphenazine on pulmonary mucociliary clearance monitored scintigraphically in the baboon model. Nucl Med Biol 1991, 18:455-459
    • (1991) Nucl Med Biol , vol.18 , pp. 455-459
    • Dormehl, I.1    Ras, G.2    Taylor, G.3    Hugo, N.4
  • 21
    • 0028208831 scopus 로고
    • Extracellular metabolites of Pseudomonas aeruginosa produce bronchoconstriction by different mechanisms
    • Forteza R, Lauredo I, Burch R, Abraham W: Extracellular metabolites of Pseudomonas aeruginosa produce bronchoconstriction by different mechanisms. Am J Respir Crit Care Med 1994, 149:687-693
    • (1994) Am J Respir Crit Care Med , vol.149 , pp. 687-693
    • Forteza, R.1    Lauredo, I.2    Burch, R.3    Abraham, W.4
  • 22
    • 0031764413 scopus 로고    scopus 로고
    • Mechanism of pyocyanin- and 1-hydroxyphenazine-induced lung neutrophilia in sheep airways
    • Lauredo I, Sabater J, Ahmed A, Botvinnikova Y, Abraham W: Mechanism of pyocyanin- and 1-hydroxyphenazine-induced lung neutrophilia in sheep airways. J Appl Physiol 1998, 85:2298-2304
    • (1998) J Appl Physiol , vol.85 , pp. 2298-2304
    • Lauredo, I.1    Sabater, J.2    Ahmed, A.3    Botvinnikova, Y.4    Abraham, W.5
  • 23
    • 3042550379 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa pyocyanin is critical for lung infection in mice
    • Lau GW, Ran HM, Kong FS, Hassett DJ, Mavrodi D: Pseudomonas aeruginosa pyocyanin is critical for lung infection in mice. Infect Immun 2004, 72:4275-4278
    • (2004) Infect Immun , vol.72 , pp. 4275-4278
    • Lau, G.W.1    Ran, H.M.2    Kong, F.S.3    Hassett, D.J.4    Mavrodi, D.5
  • 25
    • 0142226951 scopus 로고    scopus 로고
    • Microbial diversity and prevalence of virulent pathogens in biofilms developed in a water reclamation system
    • Hu JY, Fan Y, Lin YH, Zhang HB, Ong SL, Dong N, Xu JL, Ng WJ, Zhang LH: Microbial diversity and prevalence of virulent pathogens in biofilms developed in a water reclamation system. Res Microbiol 2003, 154:623-629
    • (2003) Res Microbiol , vol.154 , pp. 623-629
    • Hu, J.Y.1    Fan, Y.2    Lin, Y.H.3    Zhang, H.B.4    Ong, S.L.5    Dong, N.6    Xu, J.L.7    Ng, W.J.8    Zhang, L.H.9
  • 26
    • 21144449112 scopus 로고    scopus 로고
    • Calcium-induced virulence factors associated with the extracellular matrix of mucoid Pseudomonas aeruginosa biofilms
    • Sarkisova S, Patrauchan MA, Berglund D, Nivens DE, Franklin MJ: Calcium-induced virulence factors associated with the extracellular matrix of mucoid Pseudomonas aeruginosa biofilms. J Bacteriol 2005, 187:4327-4337
    • (2005) J Bacteriol , vol.187 , pp. 4327-4337
    • Sarkisova, S.1    Patrauchan, M.A.2    Berglund, D.3    Nivens, D.E.4    Franklin, M.J.5
  • 27
    • 0034641962 scopus 로고    scopus 로고
    • Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms
    • Singh PK, Schaefer AL, Parsek MR, Moninger TO, Welsh MJ, Greenberg EP: Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms. Nature 2000, 407:762-764
    • (2000) Nature , vol.407 , pp. 762-764
    • Singh, P.K.1    Schaefer, A.L.2    Parsek, M.R.3    Moninger, T.O.4    Welsh, M.J.5    Greenberg, E.P.6
  • 29
    • 0344198520 scopus 로고    scopus 로고
    • Human Targets of Pseudomonas aeruginosa pyocyanin
    • Ran H, Hassett DJ, Lau GW: Human Targets of Pseudomonas aeruginosa pyocyanin. Proc Natl Acad Sci USA 2003, 100:14315-14320
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 14315-14320
    • Ran, H.1    Hassett, D.J.2    Lau, G.W.3
  • 30
    • 0036318851 scopus 로고    scopus 로고
    • Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments
    • Ahmad-Nejad P, Häcker H, Rutz M, Bauer S, Vabulas RM, Wagner H: Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments. Eur J Immunol 2002, 32:1958-1968
    • (2002) Eur J Immunol , vol.32 , pp. 1958-1968
    • Ahmad-Nejad, P.1    Häcker, H.2    Rutz, M.3    Bauer, S.4    Vabulas, R.M.5    Wagner, H.6
  • 31
    • 42949086603 scopus 로고    scopus 로고
    • Identification of Francisella tularensis lipoproteins that stimulate the Toll-like receptor (TLR) 2/TLR1 heterodimer
    • Thakran S, Li H, Lavine CL, Miller MA, Bina JE, Bina XR, Re F: Identification of Francisella tularensis lipoproteins that stimulate the Toll-like receptor (TLR) 2/TLR1 heterodimer. J Biol Chem 2008, 283:3751-3760
    • (2008) J Biol Chem , vol.283 , pp. 3751-3760
    • Thakran, S.1    Li, H.2    Lavine, C.L.3    Miller, M.A.4    Bina, J.E.5    Bina, X.R.6    Re, F.7
  • 32
    • 43349086724 scopus 로고
    • Two simple media for the demonstration of pyocyanin and fluorescein
    • King EO, Ward MK, Raney DE: Two simple media for the demonstration of pyocyanin and fluorescein. J Lab Clin Med 1954, 44:301-307
    • (1954) J Lab Clin Med , vol.44 , pp. 301-307
    • King, E.O.1    Ward, M.K.2    Raney, D.E.3
  • 35
    • 0014089071 scopus 로고
    • Measurement of pulmonary emphysema
    • Thurlbeck WM: Measurement of pulmonary emphysema. Am Rev Respir Dis 1967, 95:752-764
    • (1967) Am Rev Respir Dis , vol.95 , pp. 752-764
    • Thurlbeck, W.M.1
  • 37
    • 0036087495 scopus 로고    scopus 로고
    • Distribution of intranasal instillations in mice: Effects of volume, time, body position, and anesthesia
    • Southam DS, Dolovich M, O'Byrne PM, Inman MD: Distribution of intranasal instillations in mice: effects of volume, time, body position, and anesthesia. Am J Physiol Lung Cell Mol Physiol 2002, 282:L833-L839
    • (2002) Am J Physiol Lung Cell Mol Physiol , vol.282
    • Southam, D.S.1    Dolovich, M.2    O'Byrne, P.M.3    Inman, M.D.4
  • 38
    • 0034996176 scopus 로고    scopus 로고
    • Tissue distribution of radioactivity following intranasal administration of radioactive microspheres
    • Eyles JE, Spiers ID, Williamson ED, Alpar HO: Tissue distribution of radioactivity following intranasal administration of radioactive microspheres. J Pharm Pharmacol 2001, 53:601-607
    • (2001) J Pharm Pharmacol , vol.53 , pp. 601-607
    • Eyles, J.E.1    Spiers, I.D.2    Williamson, E.D.3    Alpar, H.O.4
  • 39
    • 0035115602 scopus 로고    scopus 로고
    • Methodology for the measurement of mucociliary function in the mouse by scintigraphy
    • Foster WM, Walters DM, Longphre M, Macri K, Miller LM: Methodology for the measurement of mucociliary function in the mouse by scintigraphy. J Appl Physiol 2001, 90:1111-1117
    • (2001) J Appl Physiol , vol.90 , pp. 1111-1117
    • Foster, W.M.1    Walters, D.M.2    Longphre, M.3    Macri, K.4    Miller, L.M.5
  • 40
    • 0036779576 scopus 로고    scopus 로고
    • Functional significance of the perforin/granzyme cell death pathway
    • Trapani JA, Smyth MJ: Functional significance of the perforin/granzyme cell death pathway. Nat Rev Immunol 2002, 2:735-747
    • (2002) Nat Rev Immunol , vol.2 , pp. 735-747
    • Trapani, J.A.1    Smyth, M.J.2
  • 43
    • 33644620356 scopus 로고    scopus 로고
    • Respiratory tract mucin genes and mucin glycoproteins in health and disease
    • Rose MC, Voynow JA: Respiratory tract mucin genes and mucin glycoproteins in health and disease. Physiol Rev 2006, 86:245-278
    • (2006) Physiol Rev , vol.86 , pp. 245-278
    • Rose, M.C.1    Voynow, J.A.2
  • 45
    • 27844537859 scopus 로고    scopus 로고
    • Molecular mechanisms of and possible treatment strategies for idiopathic pulmonary fibrosis
    • Gharaee-Kermani M, Phan SH: Molecular mechanisms of and possible treatment strategies for idiopathic pulmonary fibrosis. Curr Pharm Des 2005, 11:3943-3971
    • (2005) Curr Pharm Des , vol.11 , pp. 3943-3971
    • Gharaee-Kermani, M.1    Phan, S.H.2
  • 51
    • 1542619251 scopus 로고    scopus 로고
    • IL-4 and IL-13 up-regulate intestinal trefoil factor expression: Requirement for STAT6 and de novo protein synthesis
    • Blanchard C, Durual S, Estienne M, Bouzakri K, Heim MH, Blin N, Cuber JC: IL-4 and IL-13 up-regulate intestinal trefoil factor expression: requirement for STAT6 and de novo protein synthesis. J Immunol 2004, 172:3775-3783
    • (2004) J Immunol , vol.172 , pp. 3775-3783
    • Blanchard, C.1    Durual, S.2    Estienne, M.3    Bouzakri, K.4    Heim, M.H.5    Blin, N.6    Cuber, J.C.7
  • 56
    • 0037593635 scopus 로고    scopus 로고
    • Interleukin-1β and tumor necrosis factor α induce MUC5AC overexpression through a mechanism involving ERK/p38 mitogen-activated protein kinases-MSK1-CREB activation in human airway epithelial cells
    • Song KS, Lee WJ, Chung KC, Koo JS, Yang EJ, Choi JY, Yoon JH: Interleukin-1β and tumor necrosis factor α induce MUC5AC overexpression through a mechanism involving ERK/p38 mitogen-activated protein kinases-MSK1-CREB activation in human airway epithelial cells. J Biol Chem 2003, 278:23243-23250
    • (2003) J Biol Chem , vol.278 , pp. 23243-23250
    • Song, K.S.1    Lee, W.J.2    Chung, K.C.3    Koo, J.S.4    Yang, E.J.5    Choi, J.Y.6    Yoon, J.H.7
  • 57
    • 0037592950 scopus 로고    scopus 로고
    • Stimulation of airway mucin gene expression by interleukin (IL)-17 through IL-6 paracrine/autocrine loop
    • Chen Y, Thai P, Zhao YH, Ho YS, DeSouza MM, Wu R: Stimulation of airway mucin gene expression by interleukin (IL)-17 through IL-6 paracrine/autocrine loop. J Biol Chem 2003, 278:17036-17043
    • (2003) J Biol Chem , vol.278 , pp. 17036-17043
    • Chen, Y.1    Thai, P.2    Zhao, Y.H.3    Ho, Y.S.4    DeSouza, M.M.5    Wu, R.6
  • 59
    • 16044371529 scopus 로고    scopus 로고
    • Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: Lymphocytic and eosinophilic inflammation without airway hyperreactivity
    • Rankin JA, Picarella DE, Geba G, Temann U-A, Prasad B, DiCosmo B, Tarallo A, Stripp B, Whitsett J, Flavell RA: Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: lymphocytic and eosinophilic inflammation without airway hyperreactivity. Proc Natl Acad Sci USA 1996, 93:7821-7825
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 7821-7825
    • Rankin, J.A.1    Picarella, D.E.2    Geba, G.3    Temann, U.-A.4    Prasad, B.5    DiCosmo, B.6    Tarallo, A.7    Stripp, B.8    Whitsett, J.9    Flavell, R.A.10
  • 62
    • 0032510596 scopus 로고    scopus 로고
    • Activation of NF-κB via a Src-dependent Ras-MAPK-pp90rsk pathway is required for Pseudomonas aeruginosa-induced mucin overproduction in epithelial cells
    • Li JD, Feng W, Gallup M, Kim JH, Gum J, Kim Y, Basbaum C: Activation of NF-κB via a Src-dependent Ras-MAPK-pp90rsk pathway is required for Pseudomonas aeruginosa-induced mucin overproduction in epithelial cells. Proc Natl Acad Sci USA 1999, 95:5718-5723
    • (1999) Proc Natl Acad Sci USA , vol.95 , pp. 5718-5723
    • Li, J.D.1    Feng, W.2    Gallup, M.3    Kim, J.H.4    Gum, J.5    Kim, Y.6    Basbaum, C.7
  • 65
    • 0034141938 scopus 로고    scopus 로고
    • Oxidative stress causes mucin synthesis via transactivation of epidermal growth factor receptor: Role of neutrophils
    • Takeyama K, Dabbagh K, Shim JJ, Dao-Pick T, Ueki IF, Nadel JA: Oxidative stress causes mucin synthesis via transactivation of epidermal growth factor receptor: role of neutrophils. J Immunol 2000, 164:1546-1552
    • (2000) J Immunol , vol.164 , pp. 1546-1552
    • Takeyama, K.1    Dabbagh, K.2    Shim, J.J.3    Dao-Pick, T.4    Ueki, I.F.5    Nadel, J.A.6
  • 67
    • 0023719357 scopus 로고
    • Effect of murine gamma interferon on the cellular responses to bleomycin in mice
    • Hyde DM, Henderson TS, Giri SN, Tyler NK, Stovall MY: Effect of murine gamma interferon on the cellular responses to bleomycin in mice. Exp Lung Res 1988, 14:687-704
    • (1988) Exp Lung Res , vol.14 , pp. 687-704
    • Hyde, D.M.1    Henderson, T.S.2    Giri, S.N.3    Tyler, N.K.4    Stovall, M.Y.5
  • 69
    • 0031764104 scopus 로고    scopus 로고
    • Chemokines and chemokine receptors in T cell priming and Th1/Th2-mediated responses
    • Sallusto F, Lanzavecchia A, Mackay CR: Chemokines and chemokine receptors in T cell priming and Th1/Th2-mediated responses. Immunol Today 1998, 19:568-574
    • (1998) Immunol Today , vol.19 , pp. 568-574
    • Sallusto, F.1    Lanzavecchia, A.2    Mackay, C.R.3
  • 71
    • 0027082355 scopus 로고
    • Interaction of the Pseudomonas aeruginosa secretory products pyocyanin and pyochelin generates hydroxyl radical and causes synergistic damage to endothelial cells: Implications for Pseudomonas-associated tissue injury
    • Britigan BE, Roeder TL, Rasmussen GT, Shasby DM, McCormick ML, Cox CD: Interaction of the Pseudomonas aeruginosa secretory products pyocyanin and pyochelin generates hydroxyl radical and causes synergistic damage to endothelial cells: implications for Pseudomonas-associated tissue injury J Clin Invest 1992, 90:2187-2196
    • (1992) J Clin Invest , vol.90 , pp. 2187-2196
    • Britigan, B.E.1    Roeder, T.L.2    Rasmussen, G.T.3    Shasby, D.M.4    McCormick, M.L.5    Cox, C.D.6
  • 72
    • 0036890147 scopus 로고    scopus 로고
    • Pyocyanin induces oxidative stress in human endothelial cells and modulates the glutathione redox cycle
    • Muller M: Pyocyanin induces oxidative stress in human endothelial cells and modulates the glutathione redox cycle. Free Radic Biol Med 2002, 33:1527-1533
    • (2002) Free Radic Biol Med , vol.33 , pp. 1527-1533
    • Muller, M.1


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