-
1
-
-
0035884456
-
Chloroquine-resistant malaria
-
Wellems TE, Plowe CV. Chloroquine-resistant malaria. J Infect Dis 2001; 184(6): 770-776.
-
(2001)
J Infect Dis
, vol.184
, Issue.6
, pp. 770-776
-
-
Wellems, T.E.1
Plowe, C.V.2
-
2
-
-
0027359301
-
Hemin-induced lipid membrane disorder and increased permeability: A molecular model for the mechanism of cell lysis
-
Schmitt TH, Frezzatti WA Jr, Schreier S. Hemin-induced lipid membrane disorder and increased permeability: a molecular model for the mechanism of cell lysis. Arch Biochem Biophys 1993; 307(1): 96-103.
-
(1993)
Arch Biochem Biophys
, vol.307
, Issue.1
, pp. 96-103
-
-
Schmitt, T.H.1
Frezzatti Jr., W.A.2
Schreier, S.3
-
3
-
-
0024574001
-
Oxidative effects of heme and porphyrins on proteins and lipids
-
Vincent SH. Oxidative effects of heme and porphyrins on proteins and lipids. Semin Hematol 1989; 26(2): 105-113.
-
(1989)
Semin Hematol
, vol.26
, Issue.2
, pp. 105-113
-
-
Vincent, S.H.1
-
4
-
-
19444386445
-
Free heme toxicity and its detoxification systems in human
-
Kumar S, Bandyopadhyay U. Free heme toxicity and its detoxification systems in human. Toxicol Lett 2005; 157(3): 175-188.
-
(2005)
Toxicol Lett
, vol.157
, Issue.3
, pp. 175-188
-
-
Kumar, S.1
Bandyopadhyay, U.2
-
5
-
-
0017727078
-
Host heme catabolism in drug-sensitive and drug-resistant malaria
-
Eckman JR, Modler S, Eaton JW, Berger E, Engel RR. Host heme catabolism in drug-sensitive and drug-resistant malaria. J Lab Clin Med 1977; 90(4): 767-770.
-
(1977)
J Lab Clin Med
, vol.90
, Issue.4
, pp. 767-770
-
-
Eckman, J.R.1
Modler, S.2
Eaton, J.W.3
Berger, E.4
Engel, R.R.5
-
6
-
-
0038308456
-
Neutralization of toxic heme by Plasmodium falciparum histidine-rich pro tein 2
-
Huy NT, Serada S, Trang DT, Takano R, Kondo Y, Kanaori K, Tajima K, Hara S, Kamei K. Neutralization of toxic heme by Plasmodium falciparum histidine-rich pro tein 2. J Biochem (Tokyo) 2003; 133(5): 693-698.
-
(2003)
J Biochem (Tokyo)
, vol.133
, Issue.5
, pp. 693-698
-
-
Huy, N.T.1
Serada, S.2
Trang, D.T.3
Takano, R.4
Kondo, Y.5
Kanaori, K.6
Tajima, K.7
Hara, S.8
Kamei, K.9
-
7
-
-
0030045312
-
Plasmodium hemozoin formation mediated by histidine-rich proteins
-
Sullivan DJ Jr, Gluzman IY, Goldberg DE. Plasmodium hemozoin formation mediated by histidine-rich proteins. Science 1996; 271(5246): 219-222.
-
(1996)
Science
, vol.271
, Issue.5246
, pp. 219-222
-
-
Sullivan Jr., D.J.1
Gluzman, I.Y.2
Goldberg, D.E.3
-
8
-
-
0028828562
-
Heme degradation in the presence of glutathione. A proposed mechanism to account for the high levels of non-heme iron found in the membranes of hemoglobinopathic red blood cells
-
Atamna H, Ginsburg H. Heme degradation in the presence of glutathione. A proposed mechanism to account for the high levels of non-heme iron found in the membranes of hemoglobinopathic red blood cells. J Biol Chem 1995; 270(42): 24876-24883.
-
(1995)
J Biol Chem
, vol.270
, Issue.42
, pp. 24876-24883
-
-
Atamna, H.1
Ginsburg, H.2
-
9
-
-
0036220122
-
Effect of antifungal azoles on the heme detoxification system of malarial parasite
-
Huy NT, Kamei K, Kondo Y, Serada S, Kanaori K, Takano R, Tajima K, Hara S. Effect of antifungal azoles on the heme detoxification system of malarial parasite. J Biochem (Tokyo) 2002; 131(3): 437-444.
-
(2002)
J Biochem (Tokyo)
, vol.131
, Issue.3
, pp. 437-444
-
-
Huy, N.T.1
Kamei, K.2
Kondo, Y.3
Serada, S.4
Kanaori, K.5
Takano, R.6
Tajima, K.7
Hara, S.8
-
10
-
-
0037040221
-
Clotrimazole binds to heme and enhances heme-dependent hemolysis: Proposed antimalarial mechanism of clotrimazole
-
Huy NT, Kamei K, Yamamoto T, Kondo Y, Kanaori K, Takano R, Tajima K, Hara S. Clotrimazole binds to heme and enhances heme-dependent hemolysis: proposed antimalarial mechanism of clotrimazole. J Biol Chem 2002; 277(6): 4152-4158.
-
(2002)
J Biol Chem
, vol.277
, Issue.6
, pp. 4152-4158
-
-
Huy, N.T.1
Kamei, K.2
Yamamoto, T.3
Kondo, Y.4
Kanaori, K.5
Takano, R.6
Tajima, K.7
Hara, S.8
-
12
-
-
0037101785
-
Fate of haem iron in the malaria parasite Plasmodium falciparum
-
Egan TJ, Combrinck JM, Egan J, Hearne GR, Marques HM, Ntenteni S, Sewell BT, Smith PJ, Taylor D, van Schalkwyk DA, Walden JC. Fate of haem iron in the malaria parasite Plasmodium falciparum. Biochem J 2002; 365(Pt 2): 343-347.
-
(2002)
Biochem J
, vol.365
, Issue.PART. 2
, pp. 343-347
-
-
Egan, T.J.1
Combrinck, J.M.2
Egan, J.3
Hearne, G.R.4
Marques, H.M.5
Ntenteni, S.6
Sewell, B.T.7
Smith, P.J.8
Taylor, D.9
van Schalkwyk, D.A.10
Walden, J.C.11
-
13
-
-
0037021386
-
Theories on malarial pigment formation and quinoline action
-
Sullivan DJ. Theories on malarial pigment formation and quinoline action. Int J Parasitol 2002; 32(13): 1645-1653.
-
(2002)
Int J Parasitol
, vol.32
, Issue.13
, pp. 1645-1653
-
-
Sullivan, D.J.1
-
14
-
-
43049134137
-
HDP-a novel heme detoxification protein from the malaria parasite
-
Jani D, Nagarkatti R, Beatty W, Angel R, Slebodnick C, Andersen J, Kumar S, Rathore D. HDP-a novel heme detoxification protein from the malaria parasite. PLoS Pathog 2008; 4(4): e1000053.
-
(2008)
PLoS Pathog
, vol.4
, Issue.4
-
-
Jani, D.1
Nagarkatti, R.2
Beatty, W.3
Angel, R.4
Slebodnick, C.5
Andersen, J.6
Kumar, S.7
Rathore, D.8
-
15
-
-
20444402643
-
Quinoline antimalarials decrease the rate of beta-hematin formation
-
Egan TJ, Ncokazi KK. Quinoline antimalarials decrease the rate of beta-hematin formation. J Inorg Biochem 2005; 99(7): 1532-1539.
-
(2005)
J Inorg Biochem
, vol.99
, Issue.7
, pp. 1532-1539
-
-
Egan, T.J.1
Ncokazi, K.K.2
-
16
-
-
0031021734
-
Characterization of the products of the heme detoxification pathway in malarial late trophozoites by X-ray diffraction
-
Bohle DS, Dinnebier RE, Madsen SK, Stephens PW. Characterization of the products of the heme detoxification pathway in malarial late trophozoites by X-ray diffraction. J Biol Chem 1997; 272(2): 713-716.
-
(1997)
J Biol Chem
, vol.272
, Issue.2
, pp. 713-716
-
-
Bohle, D.S.1
Dinnebier, R.E.2
Madsen, S.K.3
Stephens, P.W.4
-
17
-
-
0034673656
-
The structure of malaria pigment beta-haematin
-
Pagola S, Stephens PW, Bohle DS, Kosar AD, Madsen SK. The structure of malaria pigment beta-haematin. Nature 2000; 404(6775): 307-310.
-
(2000)
Nature
, vol.404
, Issue.6775
, pp. 307-310
-
-
Pagola, S.1
Stephens, P.W.2
Bohle, D.S.3
Kosar, A.D.4
Madsen, S.K.5
-
18
-
-
0242626690
-
Raman imaging of hemozoin within the food vacuole of Plasmodium falciparum trophozoites
-
Wood BR, Langford SJ, Cooke BM, Glenister FK, Lim J, McNaughton D. Raman imaging of hemozoin within the food vacuole of Plasmodium falciparum trophozoites. FEBS Lett 2003; 554(3): 247-252.
-
(2003)
FEBS Lett
, vol.554
, Issue.3
, pp. 247-252
-
-
Wood, B.R.1
Langford, S.J.2
Cooke, B.M.3
Glenister, F.K.4
Lim, J.5
McNaughton, D.6
-
19
-
-
0029953812
-
The iron environment in heme and heme-antimalarial complexes of pharmacological interest
-
Adams PA, Berman PA, Egan TJ, Marsh PJ, Silver J. The iron environment in heme and heme-antimalarial complexes of pharmacological interest. J Inorg Biochem 1996; 63(1): 69-77.
-
(1996)
J Inorg Biochem
, vol.63
, Issue.1
, pp. 69-77
-
-
Adams, P.A.1
Berman, P.A.2
Egan, T.J.3
Marsh, P.J.4
Silver, J.5
-
20
-
-
0034719487
-
Structure-function relationships in aminoquinolines: Effect of amino and chloro groups on quinolinehematin complex formation, inhibition of beta-hematin formation, and antiplasmodial activity
-
Egan TJ, Hunter R, Kaschula CH, Marques HM, Misplon A, Walden J. Structure-function relationships in aminoquinolines: effect of amino and chloro groups on quinolinehematin complex formation, inhibition of beta-hematin formation, and antiplasmodial activity. J Med Chem 2000; 43(2): 283-291.
-
(2000)
J Med Chem
, vol.43
, Issue.2
, pp. 283-291
-
-
Egan, T.J.1
Hunter, R.2
Kaschula, C.H.3
Marques, H.M.4
Misplon, A.5
Walden, J.6
-
21
-
-
0031018611
-
Antimalarial activity of the bisquinoline trans-N1,N2-bis (7-chloroquinolin-4-yl) cyclohexane-1,2-diamine: Comparison of two stereoisomers and detailed evaluation of the S,S enantiomer, Ro 47-7737
-
Ridley RG, Matile H, Jaquet C, Dorn A, Hofheinz W, Leupin W, Masciadri R, Theil FP, Richter WF, Girometta MA, Guenzi A, Urwyler H, Gocke E, Potthast JM, Csato M, Thomas A, Peters W. Antimalarial activity of the bisquinoline trans-N1,N2-bis (7-chloroquinolin-4-yl) cyclohexane-1,2-diamine: comparison of two stereoisomers and detailed evaluation of the S,S enantiomer, Ro 47-7737. Antimicrob Agents Chemother 1997; 41(3): 677-686.
-
(1997)
Antimicrob Agents Chemother
, vol.41
, Issue.3
, pp. 677-686
-
-
Ridley, R.G.1
Matile, H.2
Jaquet, C.3
Dorn, A.4
Hofheinz, W.5
Leupin, W.6
Masciadri, R.7
Theil, F.P.8
Richter, W.F.9
Girometta, M.A.10
Guenzi, A.11
Urwyler, H.12
Gocke, E.13
Potthast, J.M.14
Csato, M.15
Thomas, A.16
Peters, W.17
-
22
-
-
12744273601
-
Targeting the hemozoin synthesis pathway for new antimalarial drug discovery: Technologies for in vitro beta-hematin formation assay
-
Tekwani BL, Walker LA. Targeting the hemozoin synthesis pathway for new antimalarial drug discovery: technologies for in vitro beta-hematin formation assay. Comb Chem High Throughput Screen 2005; 8(1): 63-79.
-
(2005)
Comb Chem High Throughput Screen
, vol.8
, Issue.1
, pp. 63-79
-
-
Tekwani, B.L.1
Walker, L.A.2
-
23
-
-
0032919280
-
Characterisation of synthetic beta-haematin and effects of the antimalarial drugs quinidine, halofantrine, desbutylhalofantrine and mefloquine on its formation
-
Egan TJ, Hempelmann E, Mavuso WW. Characterisation of synthetic beta-haematin and effects of the antimalarial drugs quinidine, halofantrine, desbutylhalofantrine and mefloquine on its formation. J Inorg Biochem 1999; 73(1-2): 101-107.
-
(1999)
J Inorg Biochem
, vol.73
, Issue.1-2
, pp. 101-107
-
-
Egan, T.J.1
Hempelmann, E.2
Mavuso, W.W.3
-
24
-
-
0028947372
-
Malarial haemozoin/beta-haematin supports haem polymerization in the absence of protein
-
Dorn A, Stoffel R, Matile H, Bubendorf A, Ridley RG. Malarial haemozoin/beta-haematin supports haem polymerization in the absence of protein. Nature 1995; 374(6519): 269-271.
-
(1995)
Nature
, vol.374
, Issue.6519
, pp. 269-271
-
-
Dorn, A.1
Stoffel, R.2
Matile, H.3
Bubendorf, A.4
Ridley, R.G.5
-
25
-
-
0035955435
-
In vitro beta-hematin formation assays with plasma of mice infected with Plasmodium yoelii and other parasite preparations: Comparative inhibition with quinoline and endoperoxide antimalarials
-
Tripathi AK, Gupta A, Garg SK, Tekwani BL. In vitro beta-hematin formation assays with plasma of mice infected with Plasmodium yoelii and other parasite preparations: comparative inhibition with quinoline and endoperoxide antimalarials. Life Sci 2001; 69(23): 2725-2733.
-
(2001)
Life Sci
, vol.69
, Issue.23
, pp. 2725-2733
-
-
Tripathi, A.K.1
Gupta, A.2
Garg, S.K.3
Tekwani, B.L.4
-
26
-
-
33847641516
-
Alcohols induce betahematin formation via the dissociation of aggregated heme and reduction in interfacial tension of the solution
-
Huy NT, Maeda A, Uyen DT, Trang DT, Sasai M, Shiono T, Oida T, Harada S, Kamei K. Alcohols induce betahematin formation via the dissociation of aggregated heme and reduction in interfacial tension of the solution. Acta Trop 2007; 101(2): 130-138.
-
(2007)
Acta Trop
, vol.101
, Issue.2
, pp. 130-138
-
-
Huy, N.T.1
Maeda, A.2
Uyen, D.T.3
Trang, D.T.4
Sasai, M.5
Shiono, T.6
Oida, T.7
Harada, S.8
Kamei, K.9
-
27
-
-
0032942185
-
Involvement of lipids in ferriprotoporphyrin IX polymerization in malaria
-
Fitch CD, Cai GZ, Chen YF, Shoemaker JD. Involvement of lipids in ferriprotoporphyrin IX polymerization in malaria. Biochim Biophys Acta 1999; 1454(1): 31-37.
-
(1999)
Biochim Biophys Acta
, vol.1454
, Issue.1
, pp. 31-37
-
-
Fitch, C.D.1
Cai, G.Z.2
Chen, Y.F.3
Shoemaker, J.D.4
-
28
-
-
33845983685
-
Simple colorimetric inhibition assay of heme crystallization for high-throughput screening of antimalarial compounds
-
Huy NT, Uyen DT, Maeda A, Trang DT, Oida T, Harada S, Kamei K. Simple colorimetric inhibition assay of heme crystallization for high-throughput screening of antimalarial compounds. Antimicrob Agents Chemother 2007; 51(1): 350-353.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, Issue.1
, pp. 350-353
-
-
Huy, N.T.1
Uyen, D.T.2
Maeda, A.3
Trang, D.T.4
Oida, T.5
Harada, S.6
Kamei, K.7
-
29
-
-
0346728681
-
Spectrophotometric determination of de novo hemozoin/betahematin formation in an in vitro assay
-
Tripathi AK, Khan SI, Walker LA, Tekwani BL. Spectrophotometric determination of de novo hemozoin/betahematin formation in an in vitro assay. Anal Biochem 2004; 325(1): 85-91.
-
(2004)
Anal Biochem
, vol.325
, Issue.1
, pp. 85-91
-
-
Tripathi, A.K.1
Khan, S.I.2
Walker, L.A.3
Tekwani, B.L.4
-
30
-
-
0034672481
-
A role for linoleic acid in erythrocytes infected with Plasmodium berghei
-
Fitch CD, Cai GZ, Shoemaker JD. A role for linoleic acid in erythrocytes infected with Plasmodium berghei. Biochim Biophys Acta 2000; 1535(1): 45-49.
-
(2000)
Biochim Biophys Acta
, vol.1535
, Issue.1
, pp. 45-49
-
-
Fitch, C.D.1
Cai, G.Z.2
Shoemaker, J.D.3
-
31
-
-
0242408771
-
Inhibition of heme crystal growth by antimalarials and other compounds: Implications for drug discovery
-
Chong CR, Sullivan DJ Jr. Inhibition of heme crystal growth by antimalarials and other compounds: implications for drug discovery. Biochem Pharmacol 2003; 66(11): 2201-2212.
-
(2003)
Biochem Pharmacol
, vol.66
, Issue.11
, pp. 2201-2212
-
-
Chong, C.R.1
Sullivan Jr., D.J.2
-
32
-
-
0032520711
-
A comparison and analysis of several ways to promote haematin (haem) polymerisation and an assessment of its initiation in vitro
-
Dorn A, Vippagunta SR, Matile H, Bubendorf A, Vennerstrom JL, Ridley RG. A comparison and analysis of several ways to promote haematin (haem) polymerisation and an assessment of its initiation in vitro. Biochem Pharmacol 1998; 55(6): 737-747.
-
(1998)
Biochem Pharmacol
, vol.55
, Issue.6
, pp. 737-747
-
-
Dorn, A.1
Vippagunta, S.R.2
Matile, H.3
Bubendorf, A.4
Vennerstrom, J.L.5
Ridley, R.G.6
-
33
-
-
31844457268
-
Inhibition assay of beta-hematin formation initiated by lecithin for screening new antimalarial drugs
-
Trang DT, Huy NT, Uyen DT, Sasai M, Shiono T, Harada S, Kamei K. Inhibition assay of beta-hematin formation initiated by lecithin for screening new antimalarial drugs. Anal Biochem 2006; 349(2): 292-296.
-
(2006)
Anal Biochem
, vol.349
, Issue.2
, pp. 292-296
-
-
Trang, D.T.1
Huy, N.T.2
Uyen, D.T.3
Sasai, M.4
Shiono, T.5
Harada, S.6
Kamei, K.7
-
34
-
-
33745214879
-
A simple and rapid colorimetric method to measure hemozoin crystal growth in vitro
-
Huy NT, Uyen DT, Sasai M, Trang DT, Shiono T, Harada S, Kamei K. A simple and rapid colorimetric method to measure hemozoin crystal growth in vitro. Anal Biochem 2006; 354(2): 305-307.
-
(2006)
Anal Biochem
, vol.354
, Issue.2
, pp. 305-307
-
-
Huy, N.T.1
Uyen, D.T.2
Sasai, M.3
Trang, D.T.4
Shiono, T.5
Harada, S.6
Kamei, K.7
-
35
-
-
33947125517
-
Quantitative pH measurements in Plasmodium falciparum-infected erythrocytes using pHluorin
-
Kuhn Y, Rohrbach P, Lanzer M. Quantitative pH measurements in Plasmodium falciparum-infected erythrocytes using pHluorin. Cell Microbiol 2007; 9(4): 1004-1013.
-
(2007)
Cell Microbiol
, vol.9
, Issue.4
, pp. 1004-1013
-
-
Kuhn, Y.1
Rohrbach, P.2
Lanzer, M.3
-
36
-
-
34547626993
-
2-tert-butyl-8- quinolinamines exhibit potent blood schizontocidal antimalarial activity via inhibition of heme crystallization
-
Huy NT, Mizunuma K, Kaur K, Nhien NT, Jain M, Uyen DT, Harada S, Jain R, Kamei K. 2-tert-butyl-8- quinolinamines exhibit potent blood schizontocidal antimalarial activity via inhibition of heme crystallization. Antimicrob Agents Chemother 2007; 51(8): 2842-2847.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, Issue.8
, pp. 2842-2847
-
-
Huy, N.T.1
Mizunuma, K.2
Kaur, K.3
Nhien, N.T.4
Jain, M.5
Uyen, D.T.6
Harada, S.7
Jain, R.8
Kamei, K.9
-
37
-
-
0036557772
-
A non-radiolabelled ferriprotoporphyrin IX biomineralisation inhibition test for the high throughput screening of antimalarial compounds
-
Deharo E, García RN, Oporto P, Gimenez A, Sauvain M, Jullian V, Ginsburg H. A non-radiolabelled ferriprotoporphyrin IX biomineralisation inhibition test for the high throughput screening of antimalarial compounds. Exp Parasitol 2002; 100(4): 252-256.
-
(2002)
Exp Parasitol
, vol.100
, Issue.4
, pp. 252-256
-
-
Deharo, E.1
García, R.N.2
Oporto, P.3
Gimenez, A.4
Sauvain, M.5
Jullian, V.6
Ginsburg, H.7
-
38
-
-
67049173045
-
A colorimetric high throughput screen for the detection of heme crystallization inhibitors
-
Rush MA, Baniecki ML, Mazitschek R, Cortese JF, Wiegand R, Clardy J, Wirth DF. A colorimetric high throughput screen for the detection of heme crystallization inhibitors. Antimicrob Agents Chemother 2009; 53(6): 2564-2568.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, Issue.6
, pp. 2564-2568
-
-
Rush, M.A.1
Baniecki, M.L.2
Mazitschek, R.3
Cortese, J.F.4
Wiegand, R.5
Clardy, J.6
Wirth, D.F.7
|