In vitro β-hematin formation assays with plasma of mice infected with Plasmodium yoelii and other parasite preparations: Comparative inhibition with quinoline and endoperoxide antimalarials

Life Sciences

Volumn 69, Issue 23, 2001, Pages 2725-2733

  Tripathi, Abhai K ^a   Gupta, Arti ^a   Garg, Satyendra K ^b   Tekwani, Babu L ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b DR RAM MANOHAR LOHIA AVADH UNIVERSITY   (India)

Author keywords

hematin formation; Artemisinin; Hemozoin biosynthesis; Malaria; Plasmodium yoelii; Quinoline

Indexed keywords

ANTIMALARIAL AGENT; ARTEETHER; ARTEMISININ; CHLOROQUINE; ENDOPEROXIDE; HEMATIN; HEMOZOIN; LIPID; MEPACRINE; QUINALDINE; QUININE; QUINOLINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASSAY; CATALYSIS; CONTROLLED STUDY; DRUG DETOXIFICATION; DRUG INHIBITION; DRUG SCREENING; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; PLASMODIUM YOELII; PROTEIN SYNTHESIS; SCHIZONT;

ANIMALS; ANTIMALARIALS; ARTEMISININS; BIOLOGICAL ASSAY; DOSE-RESPONSE RELATIONSHIP, DRUG; ERYTHROCYTES; HEMEPROTEINS; HEMIN; MALARIA; MALE; MICE; PARASITEMIA; PEROXIDES; PLASMODIUM YOELII; QUINOLINES; SESQUITERPENES;

EID: 0035955435     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(01)01349-2     Document Type: Article

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