A comparison and analysis of several ways to promote haematin (haem) polymerisation and an assessment of its initiation in vitro

Biochemical Pharmacology

Volumn 55, Issue 6, 1998, Pages 737-747

  Dorn, Arnulf ^a   Vippagunta, Sudha Rani ^b   Matile, Hugues ^a   Bubendorf, André ^a   Vennerstrom, Jonathan L ^b   Ridley, Robert G ^a,c  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^c F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Haematin; Assay methodology; Haematin polymerisation; Initiation; Malaria; pH dependence

Indexed keywords

ACETONITRILE; AMODIAQUINE; ANTIMALARIAL AGENT; CHLOROQUINE; HALOFANTRINE; HEMATIN; HEMOZOIN; MEFLOQUINE; MEPACRINE; PRIMAQUINE; PYRONARIDINE; QUININE; RO 48 6910; UNCLASSIFIED DRUG;

ARTICLE; HEMOLYSATE; NONHUMAN; OXIDATION; PH; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN POLYMERIZATION; TEMPERATURE SENSITIVITY; TROPHOZOITE;

ACETONITRILES; ANIMALS; ANTIMALARIALS; BIOPOLYMERS; CHLOROQUINE; EVALUATION STUDIES; HEMIN; HYDROGEN-ION CONCENTRATION; PLASMODIUM FALCIPARUM; REDUCING AGENTS; TEMPERATURE;

EID: 0032520711     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(97)00509-1     Document Type: Article

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