The placenta, transfer of immunoglobulins, and safety assessment of biopharmaceuticals in pregnancy

Critical Reviews in Toxicology

Volumn 42, Issue 3, 2012, Pages 185-210

  Desesso, John M ^a,b   Williams, Amy L ^a   Ahuja, Arshiya ^b,d   Bowman, Christopher J ^c   Hurtt, Mark E ^c  

^a EXPONENT INC   (United States)

^b GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c PFIZER INC   (United States)

^d LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Biopharmaceutical safety; Fc receptors; IgG; Placenta; Placental transfer

Indexed keywords

FC RECEPTOR; IMMUNOGLOBULIN; IMMUNOGLOBULIN G; XENOBIOTIC AGENT;

AMNION FLUID; ANTIBODY DETECTION; BINDING AFFINITY; EMBRYO MEMBRANE; FETUS GROWTH; GESTATION PERIOD; HUMAN; IMMUNOGENICITY; NONHUMAN; ORGANOGENESIS; PLACENTA; PLACENTA CIRCULATION; PLACENTA DEVELOPMENT; PLACENTA FUNCTION; PLACENTAL TRANSFER; PREGNANCY; PROTEIN BINDING; REVIEW; RISK ASSESSMENT; SURFACE PROPERTY; TOXICITY;

ANIMALS; DRUG TOXICITY; FEMALE; HUMANS; IMMUNOGLOBULINS; MODELS, ANIMAL; PLACENTA; PLACENTAL CIRCULATION; PREGNANCY; RABBITS; RECEPTORS, FC; RODENTIA; XENOBIOTICS;

EID: 84857339441     PISSN: 10408444     EISSN: 15476898     Source Type: Journal    
DOI: 10.3109/10408444.2011.653487     Document Type: Review

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