An interspecies comparison of placental antibody transfer: New insights into developmental toxicity testing of monoclonal antibodies

Birth Defects Research Part B - Developmental and Reproductive Toxicology

Volumn 86, Issue 4, 2009, Pages 328-344

  Pentšuk, Nele ^a,b   Van Der Laan, Jan Willem ^a  

^a NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Interspecies comparison; Monoclonal immunoglobulins; Nonhuman primates; Placental transfer

Indexed keywords

ABATACEPT; ADALIMUMAB; ALEMTUZUMAB; BASILIXIMAB; BEVACIZUMAB; CETUXIMAB; DACLIZUMAB; ECULIZUMAB; EFALIZUMAB; ETANERCEPT; IBRITUMOMAB TIUXETAN; IMMUNOGLOBULIN G ANTIBODY; INFLIXIMAB; LEFLUNOMIDE; LUNCENTIX; MATERNAL ANTIBODY; MESALAZINE; METRONIDAZOLE; MONOCLONAL ANTIBODY; NATALIZUMAB; NAVELBINE; OMALIZUMAB; PACLITAXEL; PALIVIZUMAB; PANITUMUMAB; RANIBIZUMAB; RITUXIMAB; SULESOMAB; SULESOMAB TC 99M; TRASTUZUMAB; UNCLASSIFIED DRUG; VESTIBIX; IMMUNOGLOBULIN G;

BLOOD PLACENTA BARRIER; CAPILLARY ENDOTHELIUM; CHORIOALLANTOIS; CROHN DISEASE; DEVELOPMENTAL DISORDER; DEVELOPMENTAL TOXICITY; ECTOPIC PREGNANCY; EXPERIMENTAL GUINEA PIG; EXPERIMENTAL MONKEY; EXPERIMENTAL MOUSE; EXPERIMENTAL RABBIT; EXPERIMENTAL RAT; FALLOT TETRALOGY; HUMAN; HYPOTHYROIDISM; IMMUNE SYSTEM; INTESTINE MALROTATION; JAUNDICE; LYMPHOCYTE DEPLETION; LYMPHOCYTOPENIA; NEONATAL RESPIRATORY DISTRESS SYNDROME; NONHUMAN; OLIGOHYDRAMNIOS; ORGANOGENESIS; PASSIVE IMMUNIZATION; PLACENTAL TRANSFER; PREGNANCY OUTCOME; PREMATURITY; PRENATAL EXPOSURE; PRIORITY JOURNAL; REPRODUCTIVE TOXICITY; REVIEW; RHEUMATOID ARTHRITIS; SPECIES COMPARISON; SYNDROME VATER; YOLK SAC; ADULT; ANIMAL; COMPARATIVE STUDY; CONGENITAL MALFORMATION; DRUG SURVEILLANCE PROGRAM; FEMALE; FETOMATERNAL TRANSFUSION; GUINEA PIG; IMMUNOLOGY; METABOLISM; MOUSE; MULTIPLE MALFORMATION SYNDROME; NEWBORN; PLACENTA; PREGNANCY; PRIMATE; RABBIT; RAT; SPECIES DIFFERENCE;

ANIMALIA; CAVIA; MACACA FASCICULARIS; MUS; ORYCTOLAGUS CUNICULUS; PRIMATES; RATTUS; RODENTIA;

ABNORMALITIES, DRUG-INDUCED; ABNORMALITIES, MULTIPLE; ADULT; ADVERSE DRUG REACTION REPORTING SYSTEMS; ANIMALS; ANIMALS, NEWBORN; ANTIBODIES, MONOCLONAL; ANTIBODIES, MONOCLONAL, MURINE-DERIVED; FEMALE; GUINEA PIGS; HUMANS; IMMUNITY, MATERNALLY-ACQUIRED; IMMUNOGLOBULIN G; INFANT, NEWBORN; MATERNAL-FETAL EXCHANGE; MICE; PLACENTA; PREGNANCY; PRIMATES; RABBITS; RATS; SPECIES SPECIFICITY;

EID: 70049090959     PISSN: 15429733     EISSN: None     Source Type: Journal    
DOI: 10.1002/bdrb.20201     Document Type: Review

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