Intracellular traffic of the MHC class I-like IgG fc receptor, FcRn, expressed in epithelial MDCK cells

Journal of Cell Science

Volumn 112, Issue 14, 1999, Pages 2291-2299

  Praetor, Asja ^a   Ellinger, Isabella ^a   Hunziker, Walter ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

Fc receptor; Immunoglobulin G; Intestine; Major histocompatibility complex; Neonatal immunity; Placenta; Receptor mediated endocytosis

Indexed keywords

FC RECEPTOR; IMMUNOGLOBULIN G; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

ANIMAL CELL; ARTICLE; CELL STRAIN; COLOSTRUM; EPITHELIUM CELL; INTERNALIZATION; NONHUMAN; PASSIVE IMMUNIZATION; PLACENTA; PRIORITY JOURNAL; TRANSCYTOSIS; YOLK SAC;

ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; CELL LINE; CELL MEMBRANE; CELL POLARITY; DOGS; ENDOCYTOSIS; FEMALE; HUMANS; IMMUNITY, MATERNALLY-ACQUIRED; INFANT, NEWBORN; INTRACELLULAR FLUID; PREGNANCY; RECEPTORS, IGG; RECOMBINANT PROTEINS; TRANSFECTION;

ANIMALIA;

EID: 0032794645     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (55)

1. Apodaca, G., Enrich, C. and Mostov, K. E. (1994a). The calmodulin antagonist, W-13, alters transcytosis, recycling, and the morphology of the endocytic pathway in Madin-Darby canine kidney cells. J. Biol. Chem. 269, 19005-19013.
2. Apodaca, G., Katz, L. A. and Mostov, K. E. (1994b). Receptor-mediated transcytosis of IgA in MDCK cells is via apical recycling endosomes. J. Cell Biol. 125, 67-86.
3. Aroeti, B. and Mostov, K. E. (1994). Polarized sorting of the polymeric immunoglobulin receptor in the exocytotic and endocytotic pathways is controlled by the same amino acids. EMBO J. 13, 2297-2304.
4. Barroso, M. and Sztul, E. S. (1994). Basolateral to apical transcytosis in polarized cells is indirect and involves BFA and trimeric-G protein sensitive passage through the apical endosome. J. Cell Biol. 124, 83-100.
5. Berryman, M. and Rodewald, R. (1995). Beta-2-microglobulin codistributes with the heavy chain of the intestinal IgG-Fc receptor throughout the transepithelial transport pathway of the neonatal rat. J. Cell Sci. 108, 2347-2360.
6. Brambell, F. W. R., Brierly, J., Halliday, R. and Hemmings, W. A. (1934). Transference of passive immunity from mother to young. Lancet i, 964-965.
7. Brambell, F. W. R. and Halliday, R. (1956). The route by which passive immunity is transmitted from mother to fetus in the rat. Proc. R. Soc. Lond. B 145, 170178.
8. Brambell, F. W. R. (1970). The Transmission of Passive Immunity from Mother to Young. Amsterdam: North-Holland Publishing Co.
9. Breitfeld, P. P., McKinnon, W. C. and Mostov, K. E. (1990). Effect of nocodazole on vesicular traffic to the apical and basolateral surfaces of polarized MDCK cells. J. Cell Biol. 111, 2365-2373.
10. Cardone, M. H., Smith, B. L., Mennitt, P. A., Mochlyrosen, D., Silver, R. B. and Mostov, K. E. (1996). Signal transduction by the polymeric immunoglobulin receptor suggests a role in regulation of receptor transcytosis. J. Cell Biol. 133, 997-1005.
11. Deitcher, D. L., Neutra, M. R. and Mostov, K. E. (1986). Functional expression of the polymeric immunoglobulin receptor from cloned cDNA in fibroblasts. J. Cell Biol. 102, 911-919.
12. Ellinger, I., Schwab, M., Stefanescu, A., Hunziker, W. and Fuchs, R. (1999). IgG transport across trophoblast-derived BeWo cells: a model system to study IgG transport in the placenta. Eur. J. Immunol. 29, 733-744.
13. Ghetie, V., Hubbard, J. G., Kim, J. K., Tsen, M. F., Lee, Y. and Ward, E. S. (1996). Abnormally short serum half-lives of IgG in beta 2-microglobulin-deficient mice. Eur. J. Immunol. 26, 690-696.
14. Ghetie, V. and Ward, E. S. (1997). FcRn: the MHC class I-related receptor that is more than an IgG transporter. Immunol. Today 18, 592-598.
15. Höning, S. and Hunziker, W. (1995). Cytoplasmic determinants involved in direct lysosomal sorting, endocytosis, and basolateral targeting of rat Igp120 (lamp-I) in MDCK cells. J. Cell Biol. 128, 321-332.
16. Hunziker, W. and Mellman, I. (1989). Expression of macrophage-lymphocyte Fc receptors in MDCK cells: polarity and transcytosis differ for isoforms with or without coated pit localization domains. J. Cell Biol. 109, 3291-3302.
17. Hunziker, W., Male, P. and Mellman, I. (1990). Differential microtubule requirements for transcytosis in MDCK cells. EMBO J. 9, 3515-3525.
18. Hunziker, W., Harter, C., Matter, K. and Mellman, I. (1991a). Basolateral sorting in MDCK cells requires a distinct cytoplasmic domain determinant. Cell 66, 907-920.
19. Hunziker, W., Whitney, J. A. and Mellman, I. (1991b). Selective inhibition of transcytosis by brefeldin A in MDCK cells. Cell 67, 617-627.
20. Hunziker, W. (1994). The calmodulin antagonist W-7 affects transcytosis, lysosomal transport, and recycling but not endocytosis. J. Biol. Chem. 269, 29003-29009.
21. Hunziker, W. and Fumey, C. (1994). A di-leucine motif mediates endocytosis and basolateral sorting of macrophage IgG Fc receptors in MDCK cells. EMBO J. 13, 2963-2969.
22. Hunziker, W. and Kraehenbuhl, J.-P. (1998). Epithelial transcytosis of immunoglobulins. J. Mamm. Gland Biol. Neopl. 3, 289-304.
23. Hunziker, W. and Peters, P. J. (1998). Rab17 localizes to recycling endosomes and regulates receptor-mediated transcytosis in epithelial cells. J. Biol. Chem. 273, 15734-15741.
24. Israel, E. J., Patel, V. K., Taylor, S. F., Marshakrothstein, A. and Simister, N. (1995). Requirement for a beta(2)-microglobulin-associated Fc receptor for acquisition of maternal IgG by fetal and neonatal mice. J. Immunol. 154, 6246-6251.
25. Israel, E. J., Wilsker, D. F., Hayes, K. C., Schoenfeld, D. and Simister, N. E. (1996). Increased clearance of IgG in mice that lack beta(2)-microglobulin - possible protective role of FcRn. Immunology 89, 573-578.
26. Jones, E. A. and Waldmann, T. A. (1972). The mechanism of intestinal uptake and transcellular transport of IgG in the neonatal rat. J. Clin. Invest. 51, 2916-2927.
27. Junghans, R. P. and Anderson, C. L. (1996). The protection receptor for IgG catabolism is the beta(2)-microglobulin-containing neonatal intestinal transport receptor. Proc. Nat. Acad. Sci. USA 93, 5512-5516.
28. Kim, J. K., Tsen, M. F., Ghetie, V. and Ward, E. S. (1994). Identifying amino acid residues that influence plasma clearance of murine IgG I fragments by site-directed mutagenesis. Eur. J. Immunol. 24, 542-548.
29. Kristoffersen, E. K. and Matre, R. (1996). Co-localization of the neonatal Fc-gamma receptor and IgG in human placental term syncytiotrophoblasts. Eur. J. Immunol. 26, 1668-1671.
30. Leach, J. L., Sedmak, D. D., Osborne, J. M., Rahill, B., Lairmore, M. D. and Anderson, C. L. (1996). Isolation from human placenta of the IgG transporter, FcRn, and localization to the syncytiotrophoblast - implications for maternal-fetal antibody transport. J. Immunol. 157, 3317-3322.
31. Matter, K., Hunziker, W. and Mellman, I. (1992). Basolateral sorting of LDL receptor in MDCK cells: the cytoplasmic domain contains two tyrosine-dependent targeting determinants. Cell 71, 741-753.
32. Matter, K., Whitney, J. A., Yamamoto, E. M. and Mellman, I. (1993). Common signals control low density lipoprotein receptor sorting in endosomes and the Golgi complex of MDCK cells. Cell 74, 1053-1064.
33. Medesan, C., Radu, C., Kim, J. K., Ghetie, V. and Ward, E. S. (1996). Localization of the site of the IgG molecule that regulates maternofetal transmission in mice. Eur. J. Immunol. 26, 2533-2536.
34. Medesan, C., Matesoi, D., Radu, C., Ghetie, V. and Ward, E. S. (1997). Delineation of the amino acid residues involved in transcytosis and catabolism of mouse IgG1. J. Immunol. 158, 2211-2217.
35. Mellman, I. (1996). Endocytosis and molecular sorting. Annu. Rev. Cell Dev. Biol. 12, 575-625.
36. 125I-labelled immunoglobulin G by different regions of the gut in young rats. J. Physiol. (Lond.) 241, 761-770.
37. Mostov, K. E. and Deitcher, D. L. (1986). Polymeric immunoglobulin receptor expressed in MDCK cells transcytoses IgA. Cell 46, 613-621.
38. Nabi, I. R., Le Bivic, A., Fambrough, D. and Rodriguez-Boulan, E. (1991). An endogenous MDCK lysosomal membrane glycoprotein is targeted basolaterally before delivery to lysosomes. J. Cell Biol. 115, 1573-1584.
39. Raghavan, M. and Bjorkman, P. J. (1996). Fc receptors and their interactions with immunoglobulins. Annu. Rev. Cell Dev. Biol. 12, 181-220.
40. Roberts, D. M., Guenthert, M. and Rodewald, R. (1990) Isolation and characterization of the Fc receptor from the fetal yolk sac of the rat. J. Cell Biol. 111, 1867-1876.
41. Rock, K. L., Gamble, S., Rothstein, L., Gramm, C. and Benacerraf, B. (1991). Dissociation of b2-miroglobulin leads to the accumulation of a substantial pool of inactive class I MHC heavy chains on the cell surface. Cell 65, 611-620.
42. Rodewald, R. (1973). Intestinal transport of antibodies in the newborn rat. J. Cell Biol. 58, 189-211.
43. Rodewald, R. (1976). pH-dependent binding of immunoglobulins to intestinal cells of the neonatal rat. J. Cell Biol. 71, 666-670.
44. Rodewald, R. (1980). Distribution of immunoglobulin G receptors in the small intestine of the young rat. J. Cell Biol. 85, 18-32.
45. Sandvig, K. and Vandeurs, B. (1996). Endocytosis, intracellular transport, and cytoloxic action of shiga toxin and ricin. Physiol. Rev. 76, 949-966.
46. Simister, N. E. and Rees, A. (1985). Isolation and characterization of an Fc receptor from neonatal rat small intestine. Eur. J. Immunol. 15, 733-738.
47. Simister, N. E. and Mostov, K. E. (1989). An Fc receptor structurally related to MHC class I antigens. Nature 337, 184-187.
48. Simister, N. E., Story, C. M., Chen, H. L. and Hunt, J. S. (1996) An IgG-transporting Fc receptor expressed in the syncytiotrophoblast of human placenta. Eur. J. Immunol. 26, 1527-1531.
49. Song, W. X., Bomsel, M., Casanova, J., Vaerman, J. P. and Mostov, K. (1994). Stimulation of transcytosis of the polymeric immunoglobulin receptor by dimeric IgA. Proc. Nat. Acad. Sci. USA 91, 163-166.
50. Spriggs, M. K., Koller, B. H., Sato, T., Morrissey, P. J., Fanslow, W. C., Smithies, O., Voice, R. F., Widmer, M. B. and Maliszewski, C. R. (1992). Beta 2-microglobulin-, CD8+ T-cell-deficient mice survive inoculation with high doses of vaccinia virus and exhibit altered IgG responses. Proc. Nat. Acad. Sci. USA 89, 6070-6074.
51. Stefaner, I., Praetor, A. and Hunziker, W. (1999). Non-vectorial surface transport, endocytosis via a di-leucine based motif, and bidirectional transcytosis of chimera encoding the cytosolic tail of rat FcRn expressed in MDCK cells. J. Biol. Chem. 274, 8998-9005.
52. Story, C. M., Mikulska, J. E. and Simister, N. E. (1994). A major histocompatibility complex class I-like Fc receptor cloned from human placenta-a possible role in transfer of immunoglobulin G from mother to fetus. J. Exp. Med. 180, 2377-2381.
53. Urban, J., Parczyk, K., Leutz, A., Kayne, M. and Kondor-Koch, C. (1987). Constitutive apical secretion of an 80-kD sulfated glycoprotein complex in the polarized epithelial Madin-Darby canine kidney cell line. J. Cell Biol. 105, 2735-2743.
54. Whitney, J. A., Gomez, M., Sheff, D., Kreis, T. E. and Mellman, I. (1995). Cytoplasmic coat proteins involved in endosome function. Cell 83, 703-713.
55. Zijlstra, M., Bix, M., Simister, N. E., Loring, J. M., Raulet, D. H. and Jaenisch, R. (1990). Beta2-microglobulin deficient mice lack CD4-8+ cytolytic T cells. Nature 344, 742-746.