Synthesis and antimicrobial evaluation of some fused heterocyclic [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives

European Journal of Medicinal Chemistry

Volumn 45, Issue 12, 2010, Pages 6139-6146

  Almajan, Gabriela Laura ^a   Barbuceanu, Stefania Felicia ^a   Bancescu, Gabriela ^b   Saramet, Ioana ^a   Saramet, Gabriel ^a   Draghici, Constantin ^c  

^a CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^b Faculty of Dentistry   (Romania)

^c INSTITUTE OF ORGANIC CHEMISTRY   (Romania)

Author keywords

1,2,4 triazolo 3,4 b 1,3,4 thiadiazole; Antimicrobial activity; Cyclization; Diphenylsulfone moiety

Indexed keywords

1,2,4 TRIAZOLE DERIVATIVE; 3 [4 (4 BROMOPHENYLSULFONYL) PHENYL] 6 N (4 BROMOPHENYL) AMINO [1,2,4] TRIAZOLO [3,4 B] [1,3,4] THIADIAZOLE; 3 [4 (4 BROMOPHENYLSULFONYL) PHENYL] 6 N (4 METHOXYPHENYL) AMINO [1,2,4] TRIAZOLO [3,4 B] [1,3,4] THIADIAZOLE; 3 [4 (4 BROMOPHENYLSULFONYL) PHENYL] [1,2,4] TRIAZOLO [3,4 B] [1,3,4] THIADIAZOL 6(5H) ONE; 3 [4 (PHENYLSULFONYL) PHENYL] 6 N(4 METHYLPHENYL) AMINO [1,2,4] TRIAZOLO [3,4 B] [1,3,4] THIADIAZOLE; 3 [4 (PHENYLSULFONYL) PHENYL] [1,2,4] TRIAZOLO [3,4 B] [1,3,4] THIADIAZOL 6(5H) ONE; 6 (4 AMINOPHENYL) 3 [4 (4 BROMOPHENYLSULFONYL) PHENYL] [1,2,4] TRIAZOLO [3,4 B] [1,3,4] THIADIAZOLE; 6 (4 AMINOPHENYL) 3 [4 (PHENYLSULFONYL) PHENYL] [1,2,4] TRIAZOLO [3,4 B] [1,3,4] THIADIAZOLE; 6 (4 BROMOPHENYL) 3 [4 (4 BROMOPHENYLSULFONYL) PHENYL] [1,2,4] TRIAZOLO [3,4 B] [1,3,4] THIADIAZOLE; 6 (4 BROMOPHENYL) 3 [4 (PHENYLSULFONYL) PHENYL] [1,2,4] TRIAZOLO [3,4 B] [1,3,4] THIADIAZOLE; 6 (4 CHLOROPHENYL) 3 [4 (4 BROMOPHENYLSULFONYL) PHENYL] [1,2,4] TRIAZOLO [3,4 B] [1,3,4] THIADIAZOLE; 6 (4 CHLOROPHENYL) 3 [4 (PHENYLSULFONYL) PHENYL] [1,2,4] TRIAZOLO [3,4 B] [1,3,4] THIADIAZOLE; 6 (4 METHOXYPHENYL) 3 [4 (4 BROMOPHENYLSULFONYL) PHENYL] [1,2,4] TRIAZOLO [3,4 B] [1,3,4] THIADIAZOLE; 6 (4 METHOXYPHENYL) 3 [4 (PHENYLSULFONYL) PHENYL] [1,2,4] TRIAZOLO [3,4 B] [1,3,4] THIADIAZOLE; 6 [(3 BROMO 4 CHLORO) PHENYL] 3 [4 (4 BROMOPHENYLSULFONYL) PHENYL] [1,2,4] TRIAZOLO [3,4 B] [1,3,4] THIADIAZOLE; 6 [(3 BROMO 4 CHLORO) PHENYL] 3 [4 (PHENYLSULFONYL) PHENYL] [1,2,4] TRIAZOLO [3,4 B] [1,3,4] THIADIAZOLE; 6 [(3,4,5 TRIHYDROXYPHENYL)] 3 [4 (4 BROMOPHENYLSULFONYL) PHENYL] [1,2,4] TRIAZOLO [3,4 B] [1,3,4] THIADIAZOLE; 6 [(3,4,5 TRIHYDROXYPHENYL)] 3 [4 (PHENYLSULFONYL) PHENYL] [1,2,4] TRIAZOLO [3,4 B] [1,3,4] THIADIAZOLE; 6 [(4 AMINOMETHYL) PHENYL] 3 [4 (4 BROMOPHENYLSULFONYL) PHENYL] [1,2,4] TRIAZOLO [3,4 B] [1,3,4] THIADIAZOLE; 6 [(4 AMINOMETHYL) PHENYL] 3 [4 (PHENYLSULFONYL) PHENYL] [1,2,4] TRIAZOLO [3,4 B] [1,3,4] THIADIAZOLE; [1,2,4] TRIAZOLO [3,4 B][1,3,4] THIADIAZOLE DERIVATIVE; AMPHOTERICIN; AMPICILLIN; ANTIINFECTIVE AGENT; AROMATIC COMPOUND; AZTREONAM; DIOXANE; ISOTHIOCYANIC ACID; THIADIAZOLE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN;

ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; BACTERIA; FUNGI; HETEROCYCLIC COMPOUNDS; MOLECULAR STRUCTURE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; THIADIAZOLES;

EID: 78649324341     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.10.007     Document Type: Article

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