Synthesis and biological evaluation of 2-amino-5-sulfanyl-1,3,4-thiadiazole derivatives as antidepressant, anxiolytics and anticonvulsant agents

Medicinal Chemistry Research

Volumn 20, Issue 2, 2011, Pages 245-253

  Sharma, Rajesh ^a   Misra, Ganesh Prasad ^a   Sainy, Jitendra ^a   Chaturvedi, Subhash Chandra ^b  

^a DEVI AHILYA UNIVERSITY   (India)

^b IPS Academy   (India)

Author keywords

2 Amino 5 sulfanyl 1,3,4 thiadiazole; Antidepressant; Anxiolytic and anticonvulsant activity

Indexed keywords

1,3,4 THIADIAZOLE DERIVATIVE; 4 [5 (4 BROMOPHENYLAMINO)[1,3,4]THIADIAZOL 2 YLSULFANYL]BENZENESULFONAMIDE; 4 [5 (4 BROMOPHENYLAMINO)[1,3,4]THIADIAZOL 2 YLSULFANYL]BENZENESULFONYLCHLORIDE; 4 [5 (4 CHLOROPHENYLAMINO)[1,3,4]THIADIAZOL 2 YLSULFANYL]BENZENESULFONYLCHLORIDE; 4 [5 (4 CHLOROSULFONYLPHENYLSULFANYL)[1,3,4]THIADIAZOL 2 YLSULFANYL]BENZENESULFONYLCHLORIDE; 4 [5 (4 FLUOROPHENYLAMINO)[1,3,4]THIADIAZOL 2 YLSULFANYL]BENZENESULFONAMIDE; 4 [5 (4 FLUOROPHENYLAMINO)[1,3,4]THIADIAZOL 2 YLSULFANYL]BENZENESULFONYLCHLORIDE; 4 [5 (4 SULFAMOYLPHENYLSULFANYL)[1,3,4]THIADIAZOL 2 YLSULFANYL]BENZENESULFONAMIDE; 4 [5 (4 SULFAMOYLPHENYLSULFANYL)[1,3,4]THIADIAZOL 2 YLSULFANYL]BENZENESULFONYLCHLORIDE; 4 [5 (4 TOLYL)AMINO[1,3,4]THIADIAZOL 2 YLSULFANYL]BENZENESULFONAMIDE; 4 [5 (4 TOLYL)AMINO[1,3,4]THIADIAZOL 2 YLSULFANYL]BENZENESULFONYLCHLORIDE; 4 [5 (4 TRICHLOROMETHYLPHENYLAMINO)[1,3,4]THIADIAZOL 2 YLSULFANYL]BENZENESULFONAMIDE; 4 [5 (4 TRICHLOROMETHYLPHENYLAMINO)[1,3,4]THIADIAZOL 2 YLSULFANYL]BENZENESULFONYLCHLORIDE; 4 [5 (4 TRIFLUOROMETHYLPHENYLAMINO)[1,3,4]THIADIAZOL 2 YLSULFANYL]BENZENESULFONAMIDE; 4 [5 (4 TRIFLUOROMETHYLPHENYLAMINO)[1,3,4]THIADIAZOL 2 YLSULFANYL]BENZENESULFONYLCHLORIDE; ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; ANXIOLYTIC AGENT; BENZENESULFONAMIDE DERIVATIVE; DIAZEPAM; FLUOXETINE; PHENYTOIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ANTIDEPRESSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SYNTHESIS; EXPERIMENTAL TEST; FEMALE; FORCED SWIMMING TEST; MALE; MAZE TEST; MOUSE; NONHUMAN; TAIL SUSPENSION TEST; TRANQUILIZING ACTIVITY;

EID: 79952700851     PISSN: 10542523     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00044-010-9308-3     Document Type: Article

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