Assessing allergenicity of different tomato ecotypes by using pooled sera of allergic subjects: Identification of the main allergens

European Food Research and Technology

Volumn 234, Issue 3, 2012, Pages 405-414

  Bencivenni, Mariangela ^a   Faccini, Andrea ^a   Bottesini, Chiara ^a   Rao, Rosa ^b   Detoraki, Aikaterini ^b   Ridolo, Erminia ^a   Marone, Gianni ^b   Dall'Aglio, Pier Paolo ^a   Dossena, Arnaldo ^a   Marchelli, Rosangela ^a   Sforza, Stefano ^a  

^a UNIVERSITY OF PARMA   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Mass spectrometry; Proteomic; Tomato allergens; Tomato local varieties

Indexed keywords

ALLERGENICITY; ALLERGIC PATIENTS; BINDING PROPERTIES; CAMPANIA; HIGH RESOLUTION; MAJOR ALLERGENS; NORTHERN ITALY; PROFILIN; PROTEOMIC; PROTEOMIC APPROACHES; SOUTHERN ITALY; SPECTROMETRIC TECHNIQUES; TOMATO ALLERGENS; TOMATO LOCAL VARIETIES;

ALLERGIES; ANTIGENS; BINDING ENERGY; MASS SPECTROMETRY; PLANTS (BOTANY);

FRUITS;

EMILIA; LYCOPERSICON ESCULENTUM;

EID: 84857235594     PISSN: 14382377     EISSN: 14382385     Source Type: Journal    
DOI: 10.1007/s00217-011-1640-4     Document Type: Article

References (25)

1. Sicherer SH, Sampson HA (2009) Food allergy: recent advances in pathophysiology and treatment. Ann Rev Med 60: 261-277.
2. COMMISSION DIRECTIVE 2007/68/EC of 27 November 2007 amending Annex IIIa to Directive 2000/13/EC of the European Parliament and of the Council as regards certain food ingredients (2007) Official Journal of the European Union. http://eur-lex.europa.eu.
3. Osterballe M, Hansen TK, Mortz CG, Bindslev-Jensen C (2005) The clinical relevance of sensitization to pollen-related fruits and vegetables in unselected pollen-sensitized adults. Allergy 60: 218-225.
4. Vieths S, Scheurer S, Ballmer-Weber B (2002) Current understanding of cross-reactivity of food allergens and pollen. Ann NY Acad Sci 964: 47-68.
5. Ebner C, Hirschwehr R, Bauer L, Breiteneder H, Valenta R, Ebner H, Kraft D, Scheiner O (1995) Identification of allergens in fruits and vegetables: IgE cross-reactivities with the important birch pollen allergens Bet v 1 and Bet v 2 (birch profilin). J Allergy Clin Immunol 95: 962-969.
6. Westphal S, Kempf W, Foetisch K, Retzek M, Vieths S, Scheurer S (2004) Tomato profilin Lyc e1: IgE cross-reactivity and allergenic potency. Allergy 59: 526-532.
7. De Martino M, Novembre E, Cozza G, De Marco A, Bonazza P, Vierucci A (1988) Sensitivity to tomato and peanut allergens in children monosensitized to grass pollen. Allergy 43: 206-213.
8. Beezhold DH, Sussman GL, Liss GM, Chang NS (1996) Latex allergy can induce clinical reactions to specific foods. Clin Exp Allergy 26: 416-422.
9. Westphal S, Kolarich D, Foetisch K, Lauer I, Altmann F, Conti A, Crespo JF, Rodri{dotless}guez J, Enrique E, Vieths S, Scheurer S (2003) Molecular characterization and allergenic activity of Lyc e 2 (b-fructofuranosidase), a glycosylated allergen of tomato. Eur J Biochem 270: 1327-1337.
10. Le LQ, Lorenz Y, Scheurer S, Fötisch K, Enrique E, Bartra J, Biemelt S, Vieths S, Sonnewald U (2006) Design of tomato fruits with reduced allergenicity by dsRNAi-mediated inhibition of ns-LTP (Lyc e3) expression. Plant Biotechnol J 4: 231-242.
11. Kondo Y, Urisu A, Tokuda R (2001) Identification and characterization of the allergens in the tomato fruit. Int Arch Allergy Immunol 126: 294-299.
12. Asero R, Mistrello G, Roncarolo D, Amato S, Arcidiacono R, Fortunato D (2008) Detection of a novel allergen in raw tomato. J Investig Allergol Clin Immunol 18: 397-400.
13. Bassler OY, Weiss J, Wienkoop S, Lehmann K, Scheler C, Dolle S, Schwarz D, Franken P, George E, Worm M, Weckwerth W (2009) Evidence for novel tomato seed allergens: IgE-reactive legumin and vicilin proteins identified by multidimensional protein fractionation-mass spectrometry and in silico epitope modeling. J Proteome Res 8: 1111-1122.
14. Germini A, Paschke A, Marchelli R (2007) Preliminary studies on the effect of processing on the IgE reactivity of tomato products. J Sci Food Agric 87: 660-667.
15. Pravettoni V, Primavesi L, Farioli L, Brenna OV, Pompei C, Conti A, Scibilia J, Piantanida M, Mascheri A, Pastorello EA (2009) Tomato allergy: detection of IgE-binding lipid transfer proteins in tomato derivatives and in fresh tomato peel, pulp, and seeds. J Agric Food Chem 57: 10749-10754.
16. Le LQ, Mahler V, Lorenz Y, Scheurer S, Biemelt S, Vieths S, Sonnewald U (2006) Reduced allergenicity of tomato fruits harvested from Lyc e1-silenced transgenic tomato plants. J Allergy Clin Immunol 118: 1176-1183.
17. Breiteneder H, Radauer C (2004) A classification of plant food allergens. J Allergy Clin Immunol 113: 821-830.
18. Kitagawa M, Moriyama T, Ito H, Ozasa S, Adachi A, Yasuda J, Ookura T, Inakuma T, Kasumi T, Ishiguro Y, Ito Y (2006) Reduction of allergenic proteins by the effect of the ripening inhibitor (rin) mutant gene in an F1 hybrid of the rin mutant tomato. Biosci Biotechnol Biochem 70: 1227-1233.
19. Monaci L, Visconti A (2009) Mass spectrometry-based proteomics methods for analysis of food allergens. Trends Anal Chem 28: 581-591.
20. Yagami T, Haishima Y, Tsuchiya T, Tomitaka-Yagami A, Kano H, Matsunaga K (2004) Proteomic analysis of putative latex allergens. Int Arch Allergy Immunol 135: 3-11.
21. Rao R, Corrado G, Bianchi M, Di Mauro A (2006) (GATA)4 DNA fingerprinting identifies morphologically characterized 'San Marzano' tomato plants. Plant Breed 125: 173-176.
22. Yu LX, Nasrallah J, Valenta R, Parthasarathy MV (1998) Molecular cloning and mRNA localization of tomato pollen profilin. Plant Mol Biol 36: 699-707.
23. Weangsripanaval T, Nomura N, Moriyama T, Ohta N, Ogawa T (2003) Identification of suberization-associated anionic peroxidase as a possible allergenic protein from tomato. Biosci Biotechnol Biochem 67: 1299-1304.
24. Gaffe J, Tieman DM, Handa A (1994) Pectin methylesterase isoforms in tomato. Plant Physiol 105: 199-203.
25. Carrington CMS, Vendrell M, Domi{dotless}nguez-Puigjaner E (2002) Characterisation of an endo-(1, 4)-b-mannanase (LeMAN4) expressed in ripening tomato fruit. Plant Sci 163: 599-606.