Targeting lysophosphatidic acid signaling retards culture-associated senescence of human marrow stromal cells

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Kanehira, Masahiko ^a   Kikuchi, Toshiaki ^b   Ohkouchi, Shinya ^b   Shibahara, Taizou ^a   Tode, Naoki ^a   Santoso, Arif ^a   Daito, Hisayoshi ^a   Ohta, Hiromitsu ^b   Tamada, Tsutomu ^b   Nukiwa, Toshihiro ^a,b  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b TOHOKU UNIVERSITY HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 2A; FOCAL ADHESION KINASE; LYSOPHOSPHATIDIC ACID; LYSOPHOSPHATIDIC ACID RECEPTOR; LYSOPHOSPHATIDIC ACID RECEPTOR SUBTYPE 1; MYC PROTEIN; PHOSPHOLIPID; PROTEIN P53; RETINOBLASTOMA PROTEIN; UNCLASSIFIED DRUG; LYSOPHOSPHOLIPID;

ACTIN FILAMENT; ADIPOGENESIS; ADULT; ARTICLE; CELL AGING; CELL CYCLE G0 PHASE; CELL CYCLE REGULATION; CELL DIFFERENTIATION; CELL FUNCTION; CELL PROLIFERATION; CELL RENEWAL; CELL STRUCTURE; CLONOGENESIS; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; FEMALE; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MALE; MESENCHYMAL STROMA CELL; OSTEOBLAST; PHOSPHOLIPID SYNTHESIS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UBIQUITINATION; WESTERN BLOTTING; BONE MARROW CELL; CELL CULTURE; CELL CYCLE; CELL SHAPE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; SIGNAL TRANSDUCTION; STROMA CELL;

BONE MARROW CELLS; CELL AGING; CELL CYCLE; CELL PROLIFERATION; CELL SHAPE; CELLS, CULTURED; HUMANS; LYSOPHOSPHOLIPIDS; RECEPTORS, LYSOPHOSPHATIDIC ACID; SIGNAL TRANSDUCTION; STROMAL CELLS;

EID: 84857136113     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032185     Document Type: Article

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