Capsaicin sensitizes TRAIL-induced apoptosis through Sp1-mediated DR5 up-regulation: Involvement of Ca 2+ influx

Toxicology and Applied Pharmacology

Volumn 259, Issue 1, 2012, Pages 87-95

  Moon, Dong Oh ^a   Kang, Chang Hee ^b   Kang, Sang Hyuck ^b   Choi, Yung Hyun ^c   Hyun, Jin Won ^d   Chang, Weon Young ^d   Kang, Hee Kyoung ^d   Koh, Young Sang ^d   Maeng, Young Hee ^d   Kim, Young Ree ^d   Kim, Gi Young ^b  

^a Daegu University   (South Korea)

^b Jeju National University   (South Korea)

^c Dong Eui University   (South Korea)

^d Jeju National University School of Medicine   (South Korea)

Author keywords

Ca 2+; Capsaicin; DR5; Sp1; TRAIL

Indexed keywords

ANTINEOPLASTIC AGENT; CALCIUM; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CAPSAICIN; DEATH RECEPTOR 5; ENZYME INHIBITOR; PHOSPHATIDYLSERINE; TRANSCRIPTION FACTOR SP1; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

APOPTOSIS; ARTICLE; CALCIUM TRANSPORT; CELL SURFACE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; MITOCHONDRION; PROMOTER REGION; PROTEIN EXPRESSION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CALCIUM; CAPSAICIN; CARCINOMA, HEPATOCELLULAR; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; CELL SURVIVAL; CHROMATIN IMMUNOPRECIPITATION; DRUG RESISTANCE, NEOPLASM; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FLOW CYTOMETRY; HUMANS; LIVER NEOPLASMS; LUCIFERASES; PLASMIDS; PROMOTER REGIONS, GENETIC; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SP1 TRANSCRIPTION FACTOR; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TRANSFECTION; UP-REGULATION;

EID: 84857121509     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2011.12.010     Document Type: Article

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