Isoangustone a present in hexane/ethanol extract of Glycyrrhiza uralensis induces apoptosis in DU145 human prostate cancer cells via the activation of DR4 and intrinsic apoptosis pathway

Molecular Nutrition and Food Research

Volumn 54, Issue 9, 2010, Pages 1329-1339

  Seon, Mi Ra ^a   Lim, Soon Sung ^a   Choi, Hyun Ju ^a   Park, So Young ^a   Cho, Han Jin ^a   Kim, Jin Kyu ^a   Kim, Jongdai ^b   Kwon, Dae Young ^c   Park, Jung Han Yoon ^a  

^a Hallym University   (South Korea)

^b Kangwon National University   (South Korea)

^c Korea Food Research Institute   (South Korea)

Author keywords

Bcl 2 family proteins; Caspases; Death receptor; Glycyrrhizin; Licorice

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE; ISOANGUSTONE A; ISOFLAVONE DERIVATIVE; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PLANT EXTRACT; PROTEIN BCL 2; SMALL INTERFERING RNA; TNFRSF10A PROTEIN, HUMAN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR;

APOPTOSIS; ARTICLE; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENETICS; GLYCYRRHIZA URALENSIS; HUMAN; ISOLATION AND PURIFICATION; MALE; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; PATHOLOGY; PERMEABILITY; PROSTATE TUMOR; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CASPASES; CELL LINE, TUMOR; CELL SURVIVAL; GLYCYRRHIZA URALENSIS; HUMANS; ISOFLAVONES; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MOLECULAR STRUCTURE; PERMEABILITY; PLANT EXTRACTS; POLY(ADP-RIBOSE) POLYMERASES; PROSTATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

GLYCYRRHIZA; GLYCYRRHIZA URALENSIS;

EID: 77957085380     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.200900260     Document Type: Article

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