How to optimise antimicrobial prescriptions in the Intensive Care Unit: Principles of individualised dosing using pharmacokinetics and pharmacodynamics

International Journal of Antimicrobial Agents

Volumn 39, Issue 3, 2012, Pages 187-192

  Roberts, Jason A ^a,b,c   Joynt, Gavin M ^d   Choi, Gordon Y S ^d   Gomersall, Charles D ^d   Lipman, Jeffrey ^a,b  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^c UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^d CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Antibiotic; Creatinine clearance; Dosing; Glomerular filtration rate; Organ dysfunction; Pharmacodynamics; Therapeutic drug monitoring

Indexed keywords

AMIKACIN; AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; BETA LACTAM ANTIBIOTIC; CREATININE; POLYPEPTIDE ANTIBIOTIC AGENT; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ANTIBACTERIAL ACTIVITY; ANTIMICROBIAL THERAPY; CARDIOVASCULAR DISEASE; CREATININE CLEARANCE; CRITICALLY ILL PATIENT; DISEASES; DRUG BLOOD LEVEL; DRUG INFORMATION; DRUG MONITORING; DRUG PROTEIN BINDING; GASTROINTESTINAL DISEASE; HOSPITAL INFECTION; HUMAN; HYPOPROTEINEMIA; INTENSIVE CARE UNIT; KIDNEY CLEARANCE; LIVER FAILURE; LOADING DRUG DOSE; MINIMUM INHIBITORY CONCENTRATION; PATHOPHYSIOLOGY; PERSONALIZED MEDICINE; PHARMACODYNAMICS; PHARMACOKINETICS; PRESCRIPTION; PRIORITY JOURNAL; PROGNOSIS; REVIEW; SEPSIS;

EID: 84857060629     PISSN: 09248579     EISSN: 18727913     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2011.11.002     Document Type: Short Survey

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