Implications of augmented renal clearance in critically ill patients

Nature Reviews Nephrology

Volumn 7, Issue 9, 2011, Pages 539-543

  Udy, Andrew A ^a   Roberts, Jason A ^a   Lipman, Jeffrey ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE; ANTIINFECTIVE AGENT; BETA LACTAM ANTIBIOTIC; CREATININE; GLYCOPEPTIDE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; VANCOMYCIN; VASOACTIVE AGENT;

ACUTE KIDNEY FAILURE; ANTIMICROBIAL THERAPY; AUGMENTED RENAL CLEARANCE; BURN; CARDIOVASCULAR FUNCTION; CREATININE BLOOD LEVEL; CRITICALLY ILL PATIENT; CYSTIC FIBROSIS; DIAGNOSTIC TEST; DRUG ELIMINATION; DRUG EXPOSURE; DRUG TREATMENT FAILURE; FEBRILE NEUTROPENIA; GLOMERULUS FILTRATION RATE; HEMATOLOGIC MALIGNANCY; HUMAN; HYPERTENSION; HYPERVOLEMIA; KIDNEY CLEARANCE; KIDNEY DISEASE; KIDNEY FUNCTION; NEUROSURGERY; OUTPATIENT DEPARTMENT; PRIORITY JOURNAL; REVIEW; RISK FACTOR; SUBARACHNOID HEMORRHAGE; TRAUMATIC BRAIN INJURY; ULTRAFILTRATION;

ACUTE KIDNEY INJURY; ANTI-BACTERIAL AGENTS; ANTICOAGULANTS; CRITICAL CARE; CRITICAL ILLNESS; GLOMERULAR FILTRATION RATE; HUMANS; KIDNEY; RISK FACTORS;

EID: 80052258928     PISSN: 17595061     EISSN: 1759507X     Source Type: Journal    
DOI: 10.1038/nrneph.2011.92     Document Type: Review

References (56)

1. Udy, A. A., Putt, M. T., Shanmugathasan, S., Roberts, J. A. & Lipman, J. Augmented renal clearance in the intensive care unit: An illustrative case series. Int. J. Antimicrob. Agents 35, 606-608 (2010).
2. Dellinger, R. P. et al. Surviving sepsis campaign: International guidelines for management of severe sepsis and septic shock: 2008. Crit. Care Med. 36, 296-327 (2008).
3. Stevens, L. A., Coresh, J., Greene, T. & Levey, A. S. Assessing kidney function-measured and estimated glomerular filtration rate. N. Engl. J. Med. 354, 2473-2483 (2006). (Pubitemid 43855050)
4. Brown, R. et al. Renal function in critically ill postoperative patients: Sequential assessment of creatinine osmolar and free water clearance. Crit. Care Med. 8, 68-72 (1980).
5. Claus, B., Colpaert, K., Hoste, E. A., Decruyenaere, J. & De Waele, J. Increased glomerular filtration in the critically ill patient receiving anti-infective treatment. Crit. Care 14 (Suppl. 1), P509 (2010).
6. Fuster-Lluch, O., Geronimo-Pardo, M., Peyro-Garcia, R. & Lizan-Garcia, M. Glomerular hyperfiltration and albuminuria in critically ill patients. Anaesth. Intensive Care 36, 674-680 (2008).
7. Ibrahim, E. H., Sherman, G., Ward, S., Fraser, V. J. & Kollef, M. H. The influence of inadequate antimicrobial treatment of bloodstream infections on patient outcomes in the ICU setting. Chest 118, 146-55 (2000). (Pubitemid 30485502)
8. Udy, A. A., Roberts, J. A., Boots, R. J., Paterson, D. L. & Lipman, J. Augmented renal clearance: Implications for antibacterial dosing in the critically ill. Clin. Pharmacokinet. 49, 1-16 (2010).
9. Tett, S., Moore, S. & Ray, J. Pharmacokinetics and bioavailability of fluconazole in two groups of males with human immunodeficiency virus (HIV) infection compared with those in a group of males without HIV infection. Antimicrob. Agents Chemother. 39, 1835-1841 (1995).
10. Tett, S. E., Kirkpatrick, C. M., Gross, A. S. & McLachlan, A. J. Principles and clinical application of assessing alterations in renal elimination pathways. Clin. Pharmacokinet. 42, 1193-1211 (2003). (Pubitemid 37491486)
11. Hoste, E. A. et al. Assessment of renal function in recently admitted critically ill patients with normal serum creatinine. Nephrol. Dial. Transplant. 20, 747-753 (2005). (Pubitemid 40520652)
12. Cockcroft, D. W. & Gault, M. H. Prediction of creatinine clearance from serum creatinine. Nephron 16, 31-41 (1976).
13. Levey, A. S. et al. A more accurate method to estimate glomerular filtration rate from serum creatinine: A new prediction equation. Modification of Diet in Renal Disease Study Group. Ann. Intern. Med. 130, 461-470 (1999). (Pubitemid 29135798)
14. Martin, J. H. et al. Pitfalls of using estimations of glomerular filtration rate in an intensive care population. Intern. Med. J. doi:10.1111/j.1445-59942010.02160.x.
15. Herrera-Gutierrez, M. E. et al. Replacement of 24-h creatinine clearance by 2-h creatinine clearance in intensive care unit patients: A single-center study. Intensive Care Med. 33, 1900-1906 (2007). (Pubitemid 47632255)
16. Cherry, R. A., Eachempati, S. R., Hydo, L. & Barie, P. S. Accuracy of short-duration creatinine clearance determinations in predicting 24-hour creatinine clearance in critically ill and injured patients. J. Trauma 53, 267-271 (2002).
17. Kees, M. G., Hilpert, J. W., Gnewuch, C., Kees, F. & Voegeler, S. Clearance of vancomycin during continuous infusion in intensive care unit patients: Correlation with measured and estimated creatinine clearance and serum cystatin C. Int. J. Antimicrob. Agents 36, 545-548 (2010).
18. Lipman, J., Wallis, S. C. & Boots, R. J. Cefepime versus cefpirome: The importance of creatinine clearance. Anesth. Analg. 97, 1149-1154 (2003). (Pubitemid 37158705)
19. Udy, A. et al. Augmented creatinine clearance in traumatic brain injury. Anesth. Analg. 111, 1505-1510 (2010).
20. Sunder-Plassmann, G. & Horl, W. H. A critical appraisal for definition of hyperfiltration. Am. J. Kidney Dis. 43, 396-397 (2004).
21. Di Giantomasso, D., May, C. N. & Bellomo, R. Vital organ blood flow during hyperdynamic sepsis. Chest 124, 1053-1059 (2003). (Pubitemid 37123329)
22. Mabie, W. C., DiSessa, T. G., Crocker, L. G., Sibai, B. M. & Arheart, K. L. A longitudinal study of cardiac output in normal human pregnancy. Am. J. Obstet. Gynecol. 170, 849-856 (1994). (Pubitemid 24224713)
23. Dunlop, W. Serial changes in renal haemodynamics during normal human pregnancy. Br. J. Obstet. Gynaecol. 88, 1-9 (1981). (Pubitemid 11184002)
24. Anderson, G. D. Pregnancy-induced changes in pharmacokinetics: A mechanistic-based approach. Clin. Pharmacokinet. 44, 989-1008 (2005). (Pubitemid 41356388)
25. Wan, L., Bellomo, R. & May, C. N. The effects of normal and hypertonic saline on regional blood flow and oxygen delivery. Anesth. Analg. 105, 141-147 (2007). (Pubitemid 46975860)
26. Di Giantomasso, D., May, C. N. & Bellomo, R. Norepinephrine and vital organ blood flow during experimental hyperdynamic sepsis. Intensive Care Med. 29, 1774-1781 (2003). (Pubitemid 37373824)
27. Di Giantomasso, D., Morimatsu, H., Bellomo, R. & May, C. N. Effect of low-dose vasopressin infusion on vital organ blood flow in the conscious normal and septic sheep. Anaesth. Intensive Care 34, 427-433 (2006). (Pubitemid 44203700)
28. Castellino, P., Giordano, C., Perna, A. & DeFronzo, R. A. Effects of plasma amino acid and hormone levels on renal hemodynamics in humans. Am. J. Physiol. 255, F444-F449 (1988).
29. Thomas, D. M., Coles, G. A. & Williams, J. D. What does the renal reserve mean? Kidney Int. 45, 411-416 (1994). (Pubitemid 24065074)
30. Bratton, S. L. et al. Guidelines for the management of severe traumatic brain injury. IX. Cerebral perfusion thresholds. J. Neurotrauma 24 (Suppl. 1), S59-S64 (2007).
31. Sen, J. et al. Triple-H therapy in the management of aneurysmal subarachnoid haemorrhage. Lancet Neurol. 2, 614-621 (2003).
32. Papp, A., Uusaro, A., Parviainen, I., Hartikainen, J. & Ruokonen, E. Myocardial function and haemodynamics in extensive burn trauma: Evaluation by clinical signs, invasive monitoring, echocardiography and cytokine concentrations. A prospective clinical study. Acta Anaesthesiol. Scand. 47, 1257-1263 (2003). (Pubitemid 37452602)
33. Barton, R. G. et al. Resuscitation of thermally injured patients with oxygen transport criteria as goals of therapy. J. Burn Care Rehabil. 18, 1-9 (1997). (Pubitemid 27108215)
34. Latenser, B. A. Critical care of the burn patient: The first 48 hours. Crit. Care Med. 37, 2819-2826 (2009).
35. Palmieri, T., Lavrentieva, A. & Greenhalgh, D. G. Acute kidney injury in critically ill burn patients. Risk factors, progression and impact on mortality. Burns 36, 205-211 (2010).
36. Loirat, P. et al. Increased glomerular filtration rate in patients with major burns and its effect on the pharmacokinetics of tobramycin. N. Engl. J. Med. 299, 915-919 (1978). (Pubitemid 9050457)
37. Conil, J. M. et al. Assessment of renal function in clinical practice at the bedside of burn patients. Br. J. Clin. Pharmacol. 63, 583-594 (2007). (Pubitemid 46632572)
38. Rey, E., Treluyer, J. M. & Pons, G. Drug disposition in cystic fibrosis. Clin. Pharmacokinet. 35, 313-329 (1998). (Pubitemid 28491216)
39. Hedman, A., Alvan, G., Strandvik, B. & Arvidsson, A. Increased renal clearance of cefsulodin due to higher glomerular filtration rate in cystic fibrosis. Clin. Pharmacokinet. 18, 168-175 (1990). (Pubitemid 20104034)
40. Jusko, W. J., Mosovich, L. L., Gerbracht, L. M., Mattar, M. E. & Yaffe, S. J. Enhanced renal excretion of dicloxacillin in patients with cystic fibrosis. Pediatrics 56, 1038-1044 (1975).
41. Wang, J. P. et al. Disposition of drugs in cystic fibrosis. IV. Mechanisms for enhanced renal clearance of ticarcillin. Clin. Pharmacol. Ther. 54, 293-302 (1993).
42. Lamoth, F. et al. Reassessment of recommended imipenem doses in febrile neutropenic patients with hematological malignancies. Antimicrob. Agents Chemother. 53, 785-787 (2009).
43. Lortholary, O. et al. Pharmacodynamics and pharmacokinetics of antibacterial drugs in the management of febrile neutropenia. Lancet Infect. Dis. 8, 612-620 (2008).
44. Pea, F., Furlanut, M. & Viale, P. Is antimicrobial underexposure due to glomerular hyperfiltration a possible cause of increased mortality rate from bacterial infections in critically ill patients? Anaesth. Intensive Care 37, 323-324 (2009).
45. Roberts, J. A. & Lipman, J. Pharmacokinetic issues for antibiotics in the critically ill patient. Crit. Care Med. 37, 840-851 (2009).
46. del Mar Fernandez de Gatta Garcia, M., Revilla, N., Calvo, M. V., Dominguez-Gil, A. & Sanchez Navarro, A. Pharmacokinetic/pharmacodynamic analysis of vancomycin in ICU patients. Intensive Care Med. 33, 279-285 (2007). (Pubitemid 46221233)
47. Joukhadar, C. et al. Plasma and tissue pharmacokinetics of cefpirome in patients with sepsis. Crit. Care Med. 30, 1478-1482 (2002). (Pubitemid 34756228)
48. Kitzes-Cohen, R., Farin, D., Piva, G. & De Myttenaere-Bursztein, S. A. Pharmacokinetics and pharmacodynamics of meropenem in critically ill patients. Int. J. Antimicrob. Agents 19, 105-110 (2002). (Pubitemid 34168176)
49. Conil, J. M. et al. Influence of renal function on trough serum concentrations of piperacillin in intensive care unit patients. Intensive Care Med. 32, 2063-2066 (2006).
50. Roberts, J. A., Kruger, P., Paterson, D. L. & Lipman, J. Antibiotic resistance-what's dosing got to do with it? Crit. Care Med. 36, 2433-2440 (2008).
51. Roberts, J. A., Webb, S., Paterson, D., Ho, K. M. & Lipman, J. A systematic review on clinical benefits of continuous administration of beta-lactam antibiotics. Crit. Care Med. 37, 2071-2078 (2009).
52. Wysocki, M. et al. Continuous versus intermittent infusion of vancomycin in severe Staphylococcal infections: Prospective multicenter randomized study. Antimicrob. Agents Chemother. 45, 2460-2467 (2001). (Pubitemid 32801896)
53. Conil, J. M. et al. Tobramycin disposition in ICU patients receiving a once daily regimen: Population approach and dosage simulations. Br. J. Clin. Pharmacol. 71, 61-71 (2011).
54. Lugo, G. & Castaneda-Hernandez, G. Relationship between hemodynamic and vital support measures and pharmacokinetic variability of amikacin in critically ill patients with sepsis. Crit. Care Med. 25, 806-811 (1997). (Pubitemid 27249158)
55. Geerts, W. H. et al. Prevention of venous thromboembolism: American College of Chest Physicians evidence-based clinical practice guidelines (8th Edition). Chest 133 (6 Suppl.), 381S-453S (2008). (Pubitemid 351894916)
56. Robinson, S. et al. Enoxaparin, effective dosage for intensive care patients: Double-blinded, randomised clinical trial. Crit. Care 14, R41 (2010).