Effect of baseline serum albumin concentration on outcome of resuscitation with albumin or saline in patients in intensive care units: Analysis of data from the saline versus albumin fluid evaluation (SAFE) study

British Medical Journal

Volumn 333, Issue 7577, 2006, Pages 1044-1046

  Bellomo, Rinaldo ^a,e   McEvoy, Suzanne ^a   Kai Lo, Sing ^a,b   Myburgh, John ^a,q   Neal, Bruce ^a,b   Norton, Robyn ^a,b   French, Julie ^a,b   Finfer, Simon ^a,p   Doig, Gordon ^a,p   Hayek, Mary ^a,b   O'Donnell, Sheridan ^a,b   Bell, Anthony ^a,n   Boyce, Neil ^a,f   Blythe, David ^a,g   Cade, John ^a,o   Chapman, Marianne ^a,l   Cole, Louise ^a,j   Cooper, James ^a,c   Davies, Andrew ^a,c   French, Craig ^a,s   Joyce, Christopher ^a,k   McArthur, Colin ^a,d   MacMahon, Stephen ^a,b   Presneill, Jeffrey ^a,o   Saul, Peter ^a,h   Seppelt, Ian ^a,j   Stephens, Dianne ^a,m   Turner, Andrew ^a,n   Williams, Anthony ^a,i   Woolfe, Clive ^a,q   Sandercock, Peter ^a   Sprung, Charles ^a   Duncan Young, J ^a   Sivarajasingham, Siva ^b   Francis, Lesley ^b   Woodward, Mark ^b   Charlton, Julie ^c   Harry, Catherine ^c   Higgins, Lisa ^c   Moulden, Katherine ^c   Vallance, Shirley ^c   Chadderton, Janine ^d   Newby, Lynette ^d   Bates, Samantha ^e   Goldsmith, Donna ^e   Voss, Alison ^e   Palermo, Annamaria ^g   Jayne, Kathy ^b   Merai, Mamta ^b   Pandey, Sameer ^b   Schmidt, Manuela ^b   Carroll, Rosemary ^h   McFadyen, Brett ^h   Clarke, Jane ⁱ   Powell, Catherine ^q   Tai, Judi ⁱ   Hynesova, Iveta ^j   Weisbrodt, Leonie ^j   Bradley, Lisa ^k   Kelly, Theresa ^k   Limpus, Anthony ^k   Moore, Robyn ^k   Creed, Stephanie ^l   Kaplan, Sandra ^l   Rivett, Justine ^l   Thomas, Jane ^m   Marsden, Kathy ⁿ   Boyce, Catherine ^o   Howe, Belinda ^o   Robertson, Megan ^o   O'Connor, Anne ^p   Potter, Julie ^p   Ramakrishnan, Naresh ^p   Rajbhandari, Dorrilyn ^q   Girling, Kathryn ^r   Hodgetts, Marie ^r   Jovanovska, Alina ^r   Little, Lorraine ^s   more..

^a University of Sydney ^*

^b UNIVERSITY OF SYDNEY   (Australia)

^c ALFRED HOSPITAL   (Australia)

^d AUCKLAND CITY HOSPITAL   (New Zealand)

^e AUSTIN HEALTH   (Australia)

^f AUSTRALIAN RED CROSS BLOOD SERVICE   (Australia)

^g FREMANTLE HOSPITAL   (Australia)

^h JOHN HUNTER HOSPITAL   (Australia)

ⁱ MIDDLEMORE HOSPITAL   (New Zealand)

^j NEPEAN HOSPITAL   (Australia)

^k PRINCESS ALEXANDRA HOSPITAL   (Australia)

^l ROYAL ADELAIDE HOSPITAL   (Australia)

^m ROYAL DARWIN HOSPITAL   (Australia)

ⁿ ROYAL HOBART HOSPITAL   (Australia)

^o ROYAL MELBOURNE HOSPITAL   (Australia)

^p ROYAL NORTH SHORE HOSPITAL   (Australia)

^q ROYAL PRINCE ALFRED HOSPITAL   (Australia)

^r ST GEORGE HOSPITAL   (Australia)

^s WESTERN HOSPITAL   (Australia)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; SODIUM CHLORIDE;

ALBUMIN BLOOD LEVEL; ARTICLE; ARTIFICIAL VENTILATION; AUSTRALIA; CONTROLLED STUDY; DEATH; FLUID RESUSCITATION; HOSPITALIZATION; HUMAN; INTENSIVE CARE UNIT; LENGTH OF STAY; MAJOR CLINICAL STUDY; MORTALITY; NEW ZEALAND; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RENAL REPLACEMENT THERAPY;

EID: 33751343231     PISSN: 09598146     EISSN: None     Source Type: Journal    
DOI: 10.1136/bmj.38985.398704.7C     Document Type: Article

References (8)

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2. ANZICS Clinical Trials Group and Institute for International Health SAFE Study Investigators. The saline vs. albumin fluid evaluation (SAFE) study (ISRCTN76588266): Design and conduct of a multi-centre, blinded randomised controlled trial of intravenous fluid resuscitation in critically ill patients. http://bmj.com/cgi/contcnt/full/326/7389/559/DCl (accessed 16 Mar 2006).
3. The SAFE Study Investigators. A comparison of albumin and saline for fluid resuscitation in the intensive care unit. N Engl J Med 2004;350:2247-56.
4. Human albumin solution for resuscitation and volume expansion in critically ill patients. Cochrane Database Syst Rev 2004;(4):CD001208.pub2.
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7. Vincent JL, Navickis RJ, Wilkes MM. Morbidity in hospitalized patients receiving human albumin: a meta-analysis of randomized, controlled trials. Crit Care Med 2004;32:2029-38.
8. Cook D. Is albumin safe? N Engl J Med 2004;350:2294-6.