An experimental rat model of sporadic Alzheimer's disease and rescue of cognitive impairment with a neurotrophic peptide

Acta Neuropathologica

Volumn 123, Issue 1, 2012, Pages 133-151

  Bolognin, Silvia ^a   Blanchard, Julie ^a   Wang, Xiaochuan ^a,c   Basurto Islas, Gustavo ^a   Tung, Yunn Chyn ^a   Kohlbrenner, Erik ^b   Grundke Iqbal, Inge ^a   Iqbal, Khalid ^a  

^a NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; GLUTAMATE RECEPTOR; MESSENGER RNA; MICROTUBULE ASSOCIATED PROTEIN 2; NEUROPEPTIDE; PEPTIDE 6; PHOSPHOPROTEIN PHOSPHATASE 2A; SYNAPSIN I; SYNAPTOPHYSIN; TAU PROTEIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DENSITY; COGNITIVE DEFECT; CONTROLLED STUDY; DENTATE GYRUS; DRUG MECHANISM; ENZYME ACTIVITY; GENE EXPRESSION; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA2 REGION; MALE; NERVE CELL PLASTICITY; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR UPREGULATION; SPATIAL MEMORY; WISTAR RAT; WORKING MEMORY;

ALZHEIMER DISEASE; ANIMALS; CILIARY NEUROTROPHIC FACTOR; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; MALE; NEUROGENESIS; NEURONAL PLASTICITY; NEURONS; NEUROPROTECTIVE AGENTS; PEPTIDE FRAGMENTS; PEPTIDES; RATS; RATS, WISTAR; TAU PROTEINS;

EID: 84857032101     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-011-0908-x     Document Type: Article

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