Effects of salicylic acid in glutamate- and kainic acid-induced neurotoxicity in cerebellar granular cell culture of rats

Pharmacological Research

Volumn 42, Issue 6, 2000, Pages 547-551

  Gepdiremen, A ^a   Hacimuftuoglu A ^a   Duzenli S ^b   Oztas S ^b   Suleyman H ^a  

^a Department of Pharmacology ^*  (Turkey)

^b ATATURK UNIVERSITY   (Turkey)

Author keywords

Cell culture; Cerebellum; Glutamate; Kainic acid; Neuroprotection; Salicylic acid

Indexed keywords

GLUTAMIC ACID; KAINIC ACID; OXYGEN RADICAL; SALICYLIC ACID;

ANIMAL CELL; ARTICLE; CEREBELLUM; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; GRANULE CELL; NERVE CELL NECROSIS; NEUROPROTECTION; NEUROTOXICITY; NEWBORN; NONHUMAN; PH; PRIORITY JOURNAL; RAT;

EID: 0033710576     PISSN: 10436618     EISSN: None     Source Type: Journal    
DOI: 10.1006/phrs.2000.0717     Document Type: Article

References (24)

1. Transcriptional program coordination by NMDA-sensitive glutamate receptor stimulation in primary cultures of cerebellar neurons
2. New developments in the molecular pharmacology of AMPA and kainate receptors
3. Agonist and antagonist for excitatory amino acid receptors
4. Glutamine, nitric oxide and cell-cell signalling in the nervous system
5. Kainic acid inhibits the synaptosomal plasma membrane glutamate carrier and allows glutamate leakage from the cytoplasm but does not effect glutamate exocytosis
6. Nimodipine improves kainic acid induced neurotoxicity in cerebellar granular cell culture: A double blind dose-response study
7. NMDA receptor activation induces nitric oxide synthesis from arginine in rat brain slices
8. Contemporary issues in toxicology: Free radicals in toxicology
9. NMDA receptors increase OH radicals in vivo by using nitric oxide synthase and protein kinase C
10. Sensitive assay of hydroxyl free radical formation utilizing high pressure liquid chromatography with electrochemical detection of phenol and salicylate hydroxilation products
11. Oxidative stress, glutamate and neurodegenerative disorders
12. Estimation of hydroxyl radical content in rat brain using salicylate
13. The use of salicylate hydroxylation to detect hydroxyl radical generation in ischemic and traumatic brain injury
14. Brain hydroxyl radical generation in acute experimental head injury
15. Age related regional changes in hydroxyl radical stress and antioxidants in gerbil brain
16. Gamma aminobutiric acid B receptor mediated inhibition of adenylate cyclase in cultured cerebellar granule cells: Blockade by islet activating protein
17. Regional glucose utilization and blood flow following graded forebrain ischemia in the rat: Correlation with neuropathology
18. Temporal profile of neuronal damage in a model of transient forebrain ischemia
19. Blockade of neuronal nitric oxide synthase protects against excitotoxicity in vivo
20. Modulation of pH by neuronal activity
21. Neuroprotective effects of glutamate antagonists and extracellular acidity
22. Acute acidosis elevates malonaldehyde in rat brain in vivo
23. Molecular factors underlying selective vulnerability of motor neurons to neurodegeneration in amyotrophic lateral sclerosis
24. Neuropharmacology of AMPA and kainate receptors