Inhibition of the adenylyl cyclase toxin, edema factor, from Bacillus anthracis by a series of 18 mono- and bis-(M)ANT-substituted nucleoside 5′-triphosphates

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 385, Issue 1, 2012, Pages 57-68

  Taha, Hesham ^a   Dove, Stefan ^a   Geduhn, Jens ^a   König, Burkhard ^a   Shen, Yuequan ^b   Tang, Wei Jen ^c   Seifert, Roland ^d  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b NANKAI UNIVERSITY   (China)

^c UNIVERSITY OF CHICAGO   (United States)

^d HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Adenylyl cyclase; Bacillus anthracis; Edema factor; Fluorescence spectroscopy; MANT nucleotide; Molecular modelling

Indexed keywords

18 2',3' O BIS N METHYLANTHRANILOYL; 18 2',3' O MONO N METHYLANTHRANILOYL; ADENYLATE CYCLASE; ANTHRAX TOXIN; EDEMA FACTOR; NUCLEOSIDE TRIPHOSPHATE; NUCLEOTIDE DERIVATIVE; PURINE; PYRIMIDINE; TRYPTOPHAN; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; BACILLUS ANTHRACIS; BORDETELLA PERTUSSIS; FLUORESCENCE RESONANCE ENERGY TRANSFER; FLUORESCENCE SPECTROSCOPY; GENE MUTATION; NONHUMAN; RADIOMETRY;

ADENOSINE TRIPHOSPHATE; ADENYLATE CYCLASE; ANTIGENS, BACTERIAL; BACILLUS ANTHRACIS; BACTERIAL TOXINS; BINDING SITES; CYTOSINE NUCLEOTIDES; FLUORESCENCE RESONANCE ENERGY TRANSFER; MODELS, MOLECULAR; MUTATION;

EID: 84857005252     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-011-0688-9     Document Type: Article

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