Molecular analysis of the interaction of anthrax adenylyl cyclase toxin, edema factor, with 2'(3')-0-(A/-(methyl)anthraniloyl)-substituted purine and pyrimidine nucleotides

Molecular Pharmacology

Volumn 75, Issue 3, 2009, Pages 693-703

  Taha, Hesham M ^a   Schmidt, Jennifer ^a   Göttle, Martin ^a   Suryanarayana, Srividya ^b   Shen, Yuequan ^d   Tang, Wei Jen ^c   Gille, Andreas ^e,g   Geduhn, Jens ^a   König, Burkhard ^a   Dove, Stefan ^a   Seifert, Roland ^f  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b UNIVERSITY OF KANSAS   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

^d NANKAI UNIVERSITY   (China)

^e UNIVERSITY OF HEIDELBERG   (Germany)

^f HANNOVER MEDICAL SCHOOL   (Germany)

^g SANOFI AVENTIS DEUTSCHLAND GMBH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

(2'(3') O ANTHRANILOYL ADENOSINE 5' DIPHOSPHATE); (2'(3') O ANTHRANILOYL ADENOSINE 5' TRIPHOSPHATE); ADENYLATE CYCLASE TOXIN; ANTHRANILIC ACID DERIVATIVE; CALMODULIN; EDEMA FACTOR; EXOTOXIN; N METHYL 2' (3') O ANTHRANILOYL CYTOSINE 5' DIPHOSPHATE; N METHYL 2' (3') O ANTHRANILOYL INOSINE 5' DIPHOSPHATE; N METHYL 2' (3') O ANTHRANILOYL INOSINE 5' TRIPHOSPHATE; N METHYL 2'(3') O ANTHRANILOYL CYTOSINE 5' TRIPHOSPHATE; N METHYL 2'(3') O ANTHRANILOYL URIDINE 5' DIPHOSPHATE; N METHYL 2'(3') O ANTHRANILOYL URIDINE 5' TRIPHOSPHATE; PURINE NUCLEOTIDE; PYRIMIDINE NUCLEOTIDE; TRYPTOPHAN; TYROSINE; UNCLASSIFIED DRUG; 2'(3') O METHYLANTHRANILOYL GAMMA AMIDO ADENOSINE TRIPHOSPHATE; 2'(3')-O-METHYLANTHRANILOYL-GAMMA-AMIDO-ADENOSINE TRIPHOSPHATE; 3' O (N METHYLANTHRANILOYL)ADENOSINE 5' DIPHOSPHATE; 3'-O-(N-METHYLANTHRANILOYL)ADENOSINE 5'-DIPHOSPHATE; ADENOSINE DIPHOSPHATE; ADENYLATE CYCLASE; ADENYLYLIMIDODIPHOSPHATE; ANTHRAX TOXIN; ANTHRAX VACCINE; BACTERIAL ANTIGEN; BACTERIAL TOXIN; DRUG DERIVATIVE;

ANTHRAX; ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; DRUG INHIBITION; DRUG POTENCY; FLUORESCENCE RESONANCE ENERGY TRANSFER; KINETICS; MUTAGENESIS; PRIORITY JOURNAL; SUBSTITUTION REACTION; ANIMAL; CATTLE; CHEMISTRY; COMPARATIVE STUDY; GENETICS; METABOLISM; PROTEIN BINDING; SITE DIRECTED MUTAGENESIS; X RAY CRYSTALLOGRAPHY;

ADENOSINE DIPHOSPHATE; ADENYLATE CYCLASE; ADENYLYL IMIDODIPHOSPHATE; ANIMALS; ANTHRANILIC ACIDS; ANTHRAX VACCINES; ANTIGENS, BACTERIAL; BACTERIAL TOXINS; CATALYSIS; CATTLE; CRYSTALLOGRAPHY, X-RAY; FLUORESCENCE RESONANCE ENERGY TRANSFER; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PURINE NUCLEOTIDES; PYRIMIDINE NUCLEOTIDES;

EID: 62149085232     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.108.052340     Document Type: Article

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