Integrin-linked kinase regulates vasomotor function by preventing endothelial nitric oxide synthase uncoupling: Role in atherosclerosis

Circulation Research

Volumn 110, Issue 3, 2012, Pages 439-449

  Herranz, Beatriz ^b   Marquez, Susana ^a   Guijarro, Brenda ^a   Aracil, Enrique ^c   Aicart Ramos, Clara ^d   Rodriguez Crespo, Ignacio ^d   Rodríguez Puyol, Manuel ^a   Zaragoza, Carlos ^b   Saura, Marta ^a  

^a UNIVERSITY OF ALCALÁ   (Spain)

^b CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

^c HOSPITAL RAMÓN Y CAJAL   (Spain)

^d UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

atherosclerosis; oxidative stress; uncoupling protein

Indexed keywords

ACETYLCHOLINE; ALPHA SMOOTH MUSCLE ACTIN; CD31 ANTIGEN; CYCLIC GMP; DIHYDROBIOPTERIN; DIHYDROFOLATE REDUCTASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GELDANAMYCIN; HEAT SHOCK PROTEIN 90; INTEGRIN LINKED KINASE; NEURONAL NITRIC OXIDE SYNTHASE; NITRITE; SUPEROXIDE; TETRAHYDROBIOPTERIN; UNCOUPLING PROTEIN;

ADRENERGIC SYSTEM; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTERY ENDOTHELIUM; ARTICLE; ATHEROSCLEROSIS; CAROTID ARTERY; CELL LYSATE; CLINICAL ARTICLE; CONTROLLED STUDY; ECHOGRAPHY; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME REGULATION; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOPRECIPITATION; IN VIVO STUDY; MALE; MAMMARY ARTERY; MOUSE; NITRATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SHEAR STRESS; SIGNAL TRANSDUCTION; VASODILATATION;

AGED; AGED, 80 AND OVER; ANIMALS; ARTERIES; ATHEROSCLEROSIS; CATTLE; CELLS, CULTURED; CYCLIC GMP; DISEASE MODELS, ANIMAL; DOWN-REGULATION; ENDOTHELIUM, VASCULAR; FEMALE; HSP90 HEAT-SHOCK PROTEINS; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MIDDLE AGED; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; VASOMOTOR SYSTEM;

EID: 84856759299     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.111.253948     Document Type: Article

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