Activity and regulation of archaeal DNA alkyltransferase: Conserved protein involved in repair of DNA alkylation damage

Journal of Biological Chemistry

Volumn 287, Issue 6, 2012, Pages 4222-4231

  Perugino, Giuseppe ^a   Vettone, Antonella ^a   Illiano, Giuseppina ^a   Valenti, Anna ^a   Ferrara, Maria C ^a   Rossi, Mosè ^a   Ciaramella, Maria ^a  

^a INSTITUTE OF PROTEIN BIOCHEMISTRY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENTS; ALKYLTRANSFERASE; ARCHAEA; ARCHAEAL; ARCHAEON; CELLULAR PATHWAY; CONSERVED PROTEINS; DNA ALKYLATIONS; DNA BINDING ACTIVITY; DNA DAMAGES; GENE TRANSCRIPTIONS; GENOME STABILITY; IN-VITRO; IN-VIVO; REACTION MECHANISM; SULFOLOBUS SOLFATARICUS;

ALKYLATION; BINDING SITES; GENES; MICROORGANISMS; PROTEINS; REPAIR; TRANSCRIPTION;

DNA;

BACTERIAL DNA; DNA ALKYLTRANSFERASE; TRANSFERASE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL CELL; CONTROLLED STUDY; DNA ALKYLATION; DNA BINDING; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVITY; ENZYME REGULATION; ESCHERICHIA COLI; FLUORESCENCE; GENETIC STABILITY; GENETIC TRANSCRIPTION; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; SULFOLOBUS SOLFATARICUS; TRANSCRIPTION REGULATION;

ALKYL AND ARYL TRANSFERASES; ALKYLATION; ARCHAEAL PROTEINS; DNA DAMAGE; DNA REPAIR; DNA, ARCHAEAL; SULFOLOBUS SOLFATARICUS;

ARCHAEA; EUKARYOTA; SULFOLOBUS SOLFATARICUS;

EID: 84856753669     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.308320     Document Type: Article

References (32)

1. Pegg, A. E. (2011) Multifaceted roles of alkyltransferase and related proteins in DNA repair, DNA damage, resistance to chemotherapy, and research tools. Chem. Res. Toxicol. 24, 618-639
2. Yang, C. G., Garcia, K., and He, C. (2009) Damage detection and base flipping in direct DNA alkylation repair. ChemBioChem 10, 417-423
3. 6-alkyl-guanine-DNA alkyltransferase. Biochemistry 44, 15396-15405
4. Daniels, D. S., Mol, C. D., Arvai, A. S., Kanugula, S., Pegg, A. E., and Tainer, J. A. (2000) Active and alkylated human AGT structures: a novel zinc site, inhibitor, and extrahelical base binding. EMBO J. 19, 1719-1730 (Pubitemid 30182178)
5. 6- alkyl-guanine DNA alkyltransferase as a means to enhance chemotherapy. Cancer Treat. Rev. 32, 261-276
6. 6-alkyl-guanine- DNA alkyltransferase. Carcinogenesis 24, 625-635
7. Daniels, D. S., Woo, T. T., Luu, K. X., Noll, D. M., Clarke, N. D., Pegg, A. E., and Tainer, J. A. (2004) DNA binding and nucleotide flipping by the human DNA repair protein AGT. Nat. Struct. Mol. Biol. 11, 714-720 (Pubitemid 39014496)
8. Valenti, A., Napoli, A., Ferrara, M. C., Nadal, M., Rossi, M., and Ciaramella, M. (2006) Selective degradation of reverse gyrase and DNA fragmentation induced by alkylating agent in the archaeon Sulfolobus solfataricus. Nucleic Acids Res. 34, 2098-2108 (Pubitemid 44314207)
9. 6-methylguanine-DNA methyltransferase. Magn. Reson. Chem. 44, S71-S82
10. 6- methylguanine-DNA methyltransferase under various extreme conditions. J. Biochem. 136, 503-508
11. 6-methylguanine-DNA methyltransferase from the hyperthermophilic archaeon Pyrococcus sp. KOD1: a thermostable repair enzyme. Mol. Gen. Genet. 258, 69-77
12. 6- methylguanine-DNA methyltransferase-like protein from Thermus thermophilus interacts with a nucleotide excision repair protein. J. Biochem. 144, 267-277
13. 6-alkyl-guanine-DNA alkyltransferase from the hyperthermophiles Aquifex aeolicus and Archaeoglobus fulgidus. Biochem. J. 375, 449-455
14. She, Q., Singh, R. K., Confalonieri, F., Zivanovic, Y., Allard, G., Awayez, M. J., Chan-Weiher, C. C., Clausen, I. G., Curtis, B. A., De Moors, A., Erauso, G., Fletcher, C., Gordon, P. M., Heikamp-de Jong, I., Jeffries, A. C., Kozera, C. J., Medina, N., Peng, X., Thi-Ngoc, H. P., Redder, P., Schenk, M. E., Theriault, C., Tolstrup, N., Charlebois, R. L., Doolittle, W. F., Duguet, M., Gaasterland, T., Garrett, R. A., Ragan, M. A., Sensen, C. W., and Van der Oost, J. (2001) The complete genome of the crenarchaeon Sulfolobus solfataricus P2. Proc. Natl. Acad. Sci. 98, 7835-7840 (Pubitemid 32642647)
15. Leatherbarrow, R. J. (2004) GraFit, version 5.0, Erithacus Software Ltd., Staines, United Kingdom
16. Gautier, A., Juillerat, A., Heinis, C., Corrêa, I. R., Jr., Kindermann, M., Beaufils, F., and Johnsson, K. (2008) An engineered protein tag for multiprotein labeling in living cells. Chem. Biol. 15, 128-136 (Pubitemid 351253620)
17. Napoli, A., Valenti, A., Salerno, V., Nadal, M., Garnier, F., Rossi, M., and Ciaramella, M. (2004) Reverse gyrase recruitment to DNA after UV light irradiation in Sulfolobus solfataricus. J. Biol. Chem. 279, 33192-33198 (Pubitemid 39062964)
18. Wadsworth, R. I., and White, M. F. (2001) Identification and properties of the crenarchaeal single-stranded DNA-binding protein from Sulfolobus solfataricus. Nucleic Acids Res. 29, 914-920 (Pubitemid 32162259)
19. 6-benzylguanine to the protein. Anal. Biochem. 383, 44-51
20. 6-alkylguanine- DNA alkyltransferase. Biochem. Pharmacol. 80, 1317-1325
21. 6-alkyl- guanine-DNA alkyltransferase activity J. Nucleic Acids Article ID 632041, 9 pp.
22. Keppler, A., Gendreizig, S., Gronemeyer, T., Pick, H., Vogel, H., and Johnsson, K. (2003) A general method for the covalent labeling of fusion proteins with small molecules in vivo. Nat. Biotechnol. 21, 86-89 (Pubitemid 36055833)
23. 6-alkyl-guanine- DNA alkyltransferase with small molecules in vivo and in vitro. Methods 32, 437-444
24. 6-methylguanine-DNA methyltransferase are both required for its nuclear localization: the possible implications. EMBO J. 15, 4050-4060
25. 6-alkyl-guanine-DNA alkyltransferase. Effects of protein and DNA alkylation on complex stability. J. Biol. Chem. 278, 7973-7980
26. Valenti, A., Perugino, G., Nohmi, T., Rossi, M., and Ciaramella, M. (2009) Inhibition of translesion DNA polymerase by archaeal reverse gyrase. Nucleic Acids Res. 37, 4287-4295
27. 6-alkyl-guanine-DNA alkyltransferase. Carcinogenesis 23, 823-830
28. Hwang, C. S., Shemorry, A., and Varshavsky, A. (2009) Two proteolytic pathways regulate DNA repair by cotargeting the Mgt1 alkyl-guanine transferase. Proc. Natl. Acad. Sci. U.S.A. 106, 2142-2147
29. Kelman, Z., and White, M. F. (2005) Archaeal DNA replication and repair. Curr. Opin. Microbiol. 8, 669-676 (Pubitemid 41643035)
30. Maupin-Furlow, J. A., Humbard, M. A., Kirkland, P. A., Li, W., Reuter, C. J., Wright, A. J., and Zhou, G. (2006) Proteasomes from structure to function: perspectives from archaea. Curr. Top. Dev. Biol. Rev. 75, 125-169 (Pubitemid 44375084)
31. Makarova, K. S., and Koonin, E. V. (2010) Archaeal ubiquitin-like proteins: functional versatility and putative ancestral involvement in tRNA modification revealed by comparative genomic analysis. Archaea 2010, pii: 710303
32. Humbard, M. A., Miranda, H. V., Lim, J. M., Krause, D. J., Pritz, J. R., Zhou, G., Chen, S., Wells, L., and Maupin-Furlow, J. A. (2010) Ubiquitin-like small archaeal modifier proteins (SAMPs) in Haloferax volcanii. Nature 463, 54-60