Erratum: Antimetastatic effects of norcantharidin on hepatocellular carcinoma by transcriptional inhibition of MMP-9 through modulation of NF-kB activity (PLoS ONE (2012) 7:2 (e31055) DOI: 10.1371/journal.pone.0031055);Antimetastatic effects of norcantharidin on hepatocellular carcinoma by transcriptional inhibition of MMP-9 through modulation of NF-Kb activity

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Yeh, Chao Bin ^a,b   Hsieh, Ming Ju ^a   Hsieh, Yi Hsien ^a   Chien, Ming Hsien ^c,d   Chiou, Hui Ling ^a   Yang, Shun Fa ^a,b  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 3; NORCANTHARIDIN; NUCLEAR FACTOR; UROKINASE; 1,3 BUTADIENE DERIVATIVE; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; FUSED HETEROCYCLIC RINGS; NITRILE; PHOSPHATIDYLINOSITOL 3 KINASE; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN KINASE B; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

ARTICLE; CANCER CELL; CANCER INHIBITION; CANCER INVASION; CELL MIGRATION; CONTROLLED STUDY; DNA BINDING; DRUG CYTOTOXICITY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL CARCINOMA; METASTASIS INHIBITION; PROMOTER REGION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ZYMOGRAPHY; CELL MOTION; CELL SURVIVAL; DRUG ANTAGONISM; ENZYMOLOGY; GENETIC TRANSCRIPTION; GENETICS; LIVER CELL; LIVER TUMOR; METABOLISM; METASTASIS; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE; WOUND HEALING;

BICYCLO COMPOUNDS, HETEROCYCLIC; BUTADIENES; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL MOVEMENT; CELL SURVIVAL; HEPATOCYTES; HUMANS; LIVER NEOPLASMS; MATRIX METALLOPROTEINASE 9; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NF-KAPPA B; NITRILES; PHOSPHATIDYLINOSITOL 3-KINASES; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TRANSCRIPTION, GENETIC; UROKINASE-TYPE PLASMINOGEN ACTIVATOR; WOUND HEALING;

EID: 84856750556     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0171900     Document Type: Erratum

References (47)

1. Weng CJ, Chau CF, Hsieh YS, Yang SF, Yen GC, (2008) Lucidenic acid inhibits PMA-induced invasion of human hepatoma cells through inactivating MAPK/ERK signal transduction pathway and reducing binding activities of NF-kappaB and AP-1. Carcinogenesis 29: 147-156.
2. Yang SF, Chen MK, Hsieh YS, Yang JS, Zavras AI, et al. (2010) Antimetastatic effects of Terminalia catappa L. on oral cancer via a down-regulation of metastasis-associated proteases. Food Chem Toxicol 48: 1052-1058.
3. Gialeli C, Theocharis AD, Karamanos NK, (2011) Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting. FEBS J 278: 16-27.
4. Chu SC, Chiou HL, Chen PN, Yang SF, Hsieh YS, (2004) Silibinin inhibits the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2. Mol Carcinog 40: 143-149.
5. McCluskey A, Ackland SP, Gardiner E, Walkom CC, Sakoff JA, (2001) The inhibition of protein phosphatases 1 and 2A: a new target for rational anti-cancer drug design. Anticancer Drug Des 16: 291-303.
6. Hill TA, Stewart SG, Gordon CP, Ackland SP, Gilbert J, et al. (2008) Norcantharidin analogues: synthesis, anticancer activity and protein phosphatase 1 and 2A inhibition. Chem Med Chem 3: 1878-1892.
7. Yeh CB, Su CJ, Hwang JM, Chou MC, (2010) Therapeutic effects of cantharidin analogues without bridging ether oxygen on human hepatocellular carcinoma cells. Eur J Med Chem 45: 3981-3985.
8. Yang H, Guo W, Xu B, Li M, Cui J, (2007) Anticancer activity and mechanisms of norcantharidin-Nd3II on hepatoma. Anticancer Drugs 18: 1133-1137.
9. Yang PY, Chen MF, Kao YH, Hu DN, Chang FR, et al. (2011) Norcantharidin induces apoptosis of breast cancer cells: involvement of activities of mitogen activated protein kinases and signal transducers and activators of transcription. Toxicol In Vitro 25: 699-707.
10. Liao HF, Chen YJ, Chou CH, Wang FW, Kuo CD, (2011) Norcantharidin induces cell cycle arrest and inhibits progression of human leukemic Jurkat T cells through mitogen-activated protein kinase-mediated regulation of interleukin-2 production. Toxicol In Vitro 25: 206-212.
11. Chang C, Zhu YQ, Mei JJ, Liu SQ, Luo J, (2010) Involvement of mitochondrial pathway in NCTD-induced cytotoxicity in human hepG2 cells. J Exp Clin Cancer Res 9: 145-153.
12. Chang C, Zhu Y, Tang X, Tao W, (2011) The anti-proliferative effects of norcantharidin on human HepG2 cells in cell culture. Mol Biol Rep 38: 163-169.
13. Luan J, Duan H, Liu Q, Yagasaki K, Zhang G, (2010) Inhibitory effects of norcantharidin against human lung cancer cell growth and migration. Cytotechnology 62: 349-55.
14. Yang PY, Chen MF, Tsai CH, Hu DN, Chang FR, et al. (2010) Involvement of caspase and MAPK activities in norcantharidin-induced colorectal cancer cell apoptosis. Toxicol In Vitro 24: 766-775.
15. Chen YJ, Kuo CD, Tsai YM, Yu CC, Wang GS, et al. (2008) Norcantharidin induces anoikis through Jun-N-terminal kinase activation in CT26 colorectal cancer cells. Anticancer Drugs 19: 55-64.
16. Fan YZ, Fu JY, Zhao ZM, Chen CQ, (2007) Inhibitory effect of norcantharidin on the growth of human gallbladder carcinoma GBC-SD cells in vitro. Hepatobiliary Pancreat Dis Int 6: 72-80.
17. Chen YN, Chen JC, Yin SC, Wang GS, Tsauer W, et al. (2002) Effector mechanisms of norcantharidin-induced mitotic arrest and apoptosis in human hepatoma cells. Int J Cancer 100: 158-165.
18. Peng F, Wei YQ, Tian L, Yang L, Zhao X, et al. (2002) Induction of apoptosis by norcantharidin in human colorectal carcinoma cell lines: involvement of the CD95 receptor/ligand. J Cancer Res Clin Oncol 128: 223-230.
19. Huang Y, Liu Q, Liu K, Yagasaki K, Zhang G, (2009) Suppression of growth of highly-metastatic human breast cancer cells by norcantharidin and its mechanisms of action. Cytotechnology 59: 201-208.
20. Chen YN, Cheng CC, Chen JC, Tsauer W, Hsu SL, (2003) Norcantharidin-induced apoptosis is via the extracellular signal-regulated kinase and c-Jun-NH2-terminal kinase signaling pathways in human hepatoma HepG2 cells. Br J Pharmacol 140: 461-470.
21. An WW, Wang MW, Tashiro S, Onodera S, Ikejima T, (2004) Norcantharidin induces human melanoma A375-S2 cell apoptosis through mitochondrial and caspase pathways. J Korean Med Sci 19: 560-566.
22. Chen YJ, Chang WM, Liu YW, Lee CY, Jang YH, et al. (2009) A small-molecule metastasis inhibitor, norcantharidin, downregulates matrix metalloproteinase-9 expression by inhibiting Sp1 transcriptional activity in colorectal cancer cells. Chem Biol Interact 181: 440-446.
23. Chen YJ, Shieh CJ, Tsai TH, Kuo CD, Ho LT, et al. (2005) Inhibitory effect of norcantharidin, a derivative compound from blister beetles, on tumor invasion and metastasis in CT26 colorectal adenocarcinoma cells. Anticancer Drugs 16: 293-299.
24. Fang Y, Tian SL, Li KQ, Zhao SW, Wang ZY, (1993) Studies on antitumor agents. II: synthesis and anticancer activity of dehydrogenated carbon cyclic analogs of norcantharidin. Acta Pharmacol Sin 28: 931-935.
25. Wang GS, (1989) Medical uses of Mylabris in ancient China and recent studies. J. Ethnopharmacol 26: 147-162.
26. Wang ZD, Huang C, Li ZF, Yang J, Li BH, et al. (2010) Chrysanthemum indicum ethanolic extract inhibits invasion of hepatocellular carcinoma via regulation of MMP/TIMP balance as therapeutic target. Oncol Rep 23: 413-421.
27. Weng CJ, Chau CF, Yen GC, Liao JW, Chen DH, et al. (2009) Inhibitory Effects of Ganoderma lucidum on Tumorigenesis and Metastasis of Human Hepatoma Cells in Cells and Animal Models. J Agric Food Chem 57: 5049-57.
28. Chen PN, Hsieh YS, Chiou HL, Chu SC, (2005) Silibinin inhibits cell invasion through inactivation of both PI3K-Akt and MAPK signaling pathways. Chem Biol Interact 156: 141-150.
29. Hsiao YC, Kuo WH, Chen PN, Chang HR, Lin TH, et al. (2007) Flavanone and 20-OH flavanone inhibit metastasis of lung cancer cells via down-regulation of proteinases activities and MAPK pathway. Chem Biol Interact 167: 193-206.
30. Rao JS, (2003) Molecular mechanisms of glioma invasiveness: the role of proteases. Nat Rev Cancer 3: 489-501.
31. Westermarck J, Kahari VM, (1999) Regulation of matrix metalloproteinase expression in tumor invasion. FASEB J 13: 781-792.
32. Kim D, Kim S, Koh H, Yoon SO, Chung AS, et al. (2001) Akt/PKB promotes cancer cell invasion via increased motility and metalloproteinase production. FASEB J 15: 1953-1962.
33. Saxena NK, Sharma D, Ding X, Lin S, Marra F, et al. (2007) Concomitant Activation of the JAK/STAT, PI3K/AKT, and ERK Signaling Is Involved in Leptin-Mediated Promotion of Invasion and Migration of Hepatocellular Carcinoma Cells. Cancer Res 67: 2497-2507.
34. Aguirre Ghiso JA, Alonso DF, Farías EF, Gomez DE, de Kier Joffè EB, (1999) Deregulation of the signaling pathways controlling urokinase production. Its relationship with the invasive phenotype. Eur J Biochem 263: 295-304.
35. Sliva D, (2004) Signaling pathways responsible for cancer cell invasion as targets for cancer therapy. Curr Cancer Drug Targets 4: 327-336.
36. Takada Y, Singh S, Aggarwal BB, (2004) Identification of a p65 peptide that selectively inhibits NF-kappa B activation induced by various inflammatory stimuli and its role in down-regulation of NF-kappaB-mediated gene expression and up-regulation of apoptosis. J Biol Chem 279: 15096-15104.
37. Aggarwal BB, (2004) Nuclear factor-kappaB: the enemy within. Cancer Cell 6: 203-208.
38. Agendraprabhu P, Sudhandiran G, (2011) Astaxanthin inhibits tumor invasion by decreasing extracellular matrix production and induces apoptosis in experimental rat colon carcinogenesis by modulating the expressions of ERK-2, NFkB and COX-2. Invest New Drugs 29: 207-224.
39. Ma Y, Wang J, Liu L, Zhu H, Chen X, et al. (2011) Genistein potentiates the effect of arsenic trioxide against human hepatocellular carcinoma: role of Akt and nuclear factor-κB. Cancer Lett 301: 75-84.
40. Cimmino F, Scoppettuolo MN, Carotenuto M, De Antonellis P, Dato VD, et al. (2011) Norcantharidin impairs medulloblastoma growth by inhibition of Wnt/β-catenin signaling. J Neurooncol Jul 7. [Epub ahead of print].
41. Mosmann T, (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65: 55-63.
42. Yang SF, Yang WE, Chang HR, Chu SC, Hsieh YS, (2008) Luteolin induces apoptosis in oral squamous cancer cells. J Dent Res 87: 401-406.
43. Yang SF, Yang WE, Kuo WH, Chang HR, Chu SC, et al. (2008) Antimetastatic potentials of flavones on oral cancer cell via an inhibition of matrix-degrading proteases. Arch Oral Biol 53: 287-294.
44. Chu SC, Yang SF, Liu SJ, Kuo WH, Chang YZ, et al. (2007) In vitro and in vivo antimetastatic effects of Terminalia catappa L. Leaves on lung cancer cells. Food Chem Toxicol 45: 1194-1201.
45. Yang SF, Chu SC, Liu SJ, Chen YC, Chang YZ, et al. (2007) Antimetastatic activities of Selaginella tamariscina (Beauv.) on lung cancer cells in vitro and in vivo. J. Ethnopharmacol 110: 483-489.
46. Yang SF, Chen MK, Hsieh YS, Chung TT, Hsieh YH, et al. (2010) Prostaglandin E2/EP1 signaling pathway enhances intercellular adhesion molecule 1 (ICAM-1) expression and cell motility in oral cancer cells. J Biol Chem 285: 29808-29816.
47. Bradford MM, (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254.