Involvement of caspase and MAPK activities in norcantharidin-induced colorectal cancer cell apoptosis

Toxicology in Vitro

Volumn 24, Issue 3, 2010, Pages 766-775

  Yang, Pei Yu ^a,b   Chen, Ming Feng ^b   Tsai, Chi Hong ^b   Hu, Dan Ning ^b   Chang, Fang Rong ^a   Wu, Yang Chang ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b SHOW CHWAN MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Caspases; Chemosensitivity; Colorectal cancer; Mitogen activated protein kinase; Norcantharidin

Indexed keywords

CASPASE; CASPASE 3; CASPASE 8; CASPASE 9; CASPASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; NORCANTHARIDIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CHROMATIN CONDENSATION; COLORECTAL CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SENSITIVITY; ENZYME ACTIVITY; FEMALE; FRAGMENTATION REACTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MALE; PRIMARY TUMOR; SEX DIFFERENCE; SKIN FIBROBLAST;

AGED; ANTINEOPLASTIC AGENTS; APOPTOSIS; BICYCLO COMPOUNDS, HETEROCYCLIC; BLOTTING, WESTERN; CASPASES; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; CYTOCHROMES C; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROBLASTS; FLUORESCENT DYES; HISTONES; HUMANS; INDOLES; MALE; MIDDLE AGED; MITOGEN-ACTIVATED PROTEIN KINASES;

EID: 77649186034     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2009.12.025     Document Type: Article

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