Monitoring Phospholipid Dynamics during Phagocytosis: Application of Genetically-Encoded Fluorescent Probes

Methods in Cell Biology

Volumn 108, Issue , 2012, Pages 429-444

  Sarantis, Helen ^a   Grinstein, Sergio ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Extracellular; Phagocytosis; Second messenger; Sensitivity; Specificity; Transfection

Indexed keywords

EID: 84856716170     PISSN: 0091679X     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-386487-1.00019-5     Document Type: Chapter

References (50)

1. Aderem A., Underhill D.M. Mechanisms of phagocytosis in macrophages. Annu. Rev. Immunol. 1999, 17:593-623.
2. Andersson H., et al. Protein targeting to endoplasmic reticulum by dilysine signals involves direct retention in addition to retrieval. J. Biol. Chem. 1999, 274:15080-15084.
3. Andree H.A., et al. Binding of vascular anticoagulant alpha (VAC alpha) to planar phospholipid bilayers. J. Biol. Chem. 1990, 265:4923-4928.
4. Araki N., et al. A role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis by macrophages. J. Cell Biol. 1996, 135:1249-1260.
5. Axelrod D. Cell-substrate contacts illuminated by total internal reflection fluoresce'nce. J. Cell Biol. 1981, 89:141-145.
6. Balla T., Varnai P. Visualizing cellular phosphoinositide pools with GFP-fused protein-modules. Sci. STKE 2002, 2002:pl3.
7. Bohdanowicz M., et al. Class I and class III phosphoinositide 3-kinases are required for actin polymerization that propels phagosomes. J. Cell Biol. 2010, 191:999-1012.
8. Botelho R.J., et al. Localized biphasic changes in phosphatidylinositol-4,5-bisphosphate at sites of phagocytosis. J. Cell Biol. 2000, 151:1353-1368.
9. Chang-Ileto B., et al. Synaptojanin 1-mediated PI(4,5)P2 hydrolysis is modulated by membrane curvature and facilitates membrane fission. Dev. Cell 2011, 20:206-218.
10. Chen J., et al. Selective binding of phorbol esters and diacylglycerol by individual C1 domains of the PKD family. Biochem. J. 2008, 411:333-342.
11. Choy E., et al. Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi. Cell 1999, 98:69-80.
12. Colon-Gonzalez F., Kazanietz M.G. C1 domains exposed: from diacylglycerol binding to protein-protein interactions. Biochim. Biophys. Acta 2006, 1761:827-837.
13. Cox D., et al. A requirement for phosphatidylinositol 3-kinase in pseudopod extension. J. Biol. Chem. 1999, 274:1240-1247.
14. Dormann D., et al. Visualizing PI3 kinase-mediated cell-cell signaling during Dictyostelium development. Curr. Biol. 2002, 12:1178-1188.
15. Dove S.K., et al. Svp1p defines a family of phosphatidylinositol 3,5-bisphosphate effectors. EMBO J. 2004, 23:1922-1933.
16. Dowler S., et al. Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities. Biochem J. 2000, 351:19-31.
17. Downey G.P., et al. Phagosomal maturation, acidification, and inhibition of bacterial growth in nonphagocytic cells transfected with FcgammaRIIA receptors. J. Biol. Chem. 1999, 274:28436-28444.
18. Ellson C.D., et al. PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40(phox). Nat. Cell Biol. 2001, 3:679-682.
19. Emi N., et al. Pseudotype formation of murine leukemia virus with the G protein of vesicular stomatitis virus. J. Virol. 1991, 65:1202-1207.
20. Gillooly D.J., et al. Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells. EMBO J. 2000, 19:4577-4588.
21. Godi A., et al. FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P. Nat. Cell Biol. 2004, 6:393-404.
22. Gray A., et al. The pleckstrin homology domains of protein kinase B and GRP1 (general receptor for phosphoinositides-1) are sensitive and selective probes for the cellular detection of phosphatidylinositol 3,4-bisphosphate and/or phosphatidylinositol 3,4,5-trisphosphate in vivo. Biochem. J. 1999, 344(Pt 3):929-936.
23. Gu H., et al. Critical role for scaffolding adapter Gab2 in Fc gamma R-mediated phagocytosis. J. Cell Biol. 2003, 161:1151-1161.
24. Hill P.E., Walton P.A. Import of microinjected proteins bearing the SKL peroxisomal targeting sequence into the peroxisomes of a human fibroblast cell line: evidence that virtually all peroxisomes are import-competent. J. Cell Sci. 1995, 108(Pt 4):1469-1476.
25. Huynh K.K., et al. Fusion, fission, and secretion during phagocytosis. Physiology (Bethesda) 2007, 22:366-372.
26. Kimber W.A., et al. Evidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain-containing protein MUPP1 in vivo. Biochem. J. 2002, 361:525-536.
27. Kobayashi T., Arakawa Y. Transport of exogenous fluorescent phosphatidylserine analogue to the Golgi apparatus in cultured fibroblasts. J. Cell Biol. 1991, 113:235-244.
28. Komander D., et al. Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates. EMBO J. 2004, 23:3918-3928.
29. Li S.K., et al. Identification of functionally important amino acid residues in the mitochondria targeting sequence of hepatitis B virus X protein. Virology 2008, 381:81-88.
30. Liao F., et al. Tyrosine phosphorylation of phospholipase C-gamma 1 induced by cross-linking of the high-affinity or low-affinity Fc receptor for IgG in U937 cells. Proc. Natl. Acad. Sci. U. S. A. 1992, 89:3659-3663.
31. Magalhaes M.A., et al. Expression and translocation of fluorescent-tagged p21-activated kinase-binding domain and PH domain of protein kinase B during murine neutrophil chemotaxis. J. Leukoc. Biol. 2007, 82:559-566.
32. Mattheyses A.L., et al. Imaging with total internal reflection fluorescence microscopy for the cell biologist. J. Cell Sci. 2010, 123:3621-3628.
33. Nishio M., et al. Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1. Nat. Cell Biol. 2007, 9:36-44.
34. Nishioka T., et al. Heterogeneity of phosphatidic acid levels and distribution at the plasma membrane in living cells as visualized by a Foster resonance energy transfer (FRET) biosensor. J. Biol. Chem. 2010, 285:35979-35987.
35. Raiborg C., et al. FYVE and coiled-coil domains determine the specific localisation of Hrs to early endosomes. J. Cell Sci. 2001, 114:2255-2263.
36. Roy A., Levine T.P. Multiple pools of phosphatidylinositol 4-phosphate detected using the pleckstrin homology domain of Osh2p. J. Biol. Chem. 2004, 279:44683-44689.
37. Rusten T.E., Stenmark H. Analyzing phosphoinositides and their interacting proteins. Nat. Methods 2006, 3:251-258.
38. Santagata S., et al. G-protein signaling through tubby proteins. Science 2001, 292:2041-2050.
39. Sato M., et al. Production of PtdInsP3 at endomembranes is triggered by receptor endocytosis. Nat. Cell Biol. 2003, 5:1016-1022.
40. Sato M., et al. Imaging diacylglycerol dynamics at organelle membranes. Nat. Methods 2006, 3:797-799.
41. Stauffer T.P., et al. Receptor-induced transient reduction in plasma membrane PtdIns(4,5)P2 concentration monitored in living cells. Curr. Biol. 1998, 8:343-346.
42. Suh B.C., et al. Rapid chemically induced changes of PtdIns(4,5)P2 gate KCNQ ion channels. Science 2006, 314:1454-1457.
43. Swanson J.A. Shaping cups into phagosomes and macropinosomes. Nat. Rev. Mol. Cell Biol. 2008, 9:639-649.
44. Swanson J.A., Hoppe A.D. The coordination of signaling during Fc receptor-mediated phagocytosis. J. Leukoc. Biol. 2004, 76:1093-1103.
45. Teruel M.N., et al. A versatile microporation technique for the transfection of cultured CNS neurons. J. Neurosci. Methods 1999, 93:37-48.
46. Varnai P., et al. Phosphatidylinositol 3-kinase-dependent membrane association of the Bruton's tyrosine kinase pleckstrin homology domain visualized in single living cells. J. Biol. Chem. 1999, 274:10983-10989.
47. Venkateswarlu K., et al. Insulin-dependent translocation of ARNO to the plasma membrane of adipocytes requires phosphatidylinositol 3-kinase. Curr. Biol. 1998, 8:463-466.
48. Vieira O.V., et al. Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation. J. Cell Biol. 2001, 155:19-25.
49. Weischenfeldt J., et al. NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements. Genes Dev. 2008, 22:1381-1396.
50. Yeung T., et al. Membrane phosphatidylserine regulates surface charge and protein localization. Science 2008, 319:210-213.