Selective binding of phorbol esters and diacylglycerol by individual C1 domains of the PKD family

Biochemical Journal

Volumn 411, Issue 2, 2008, Pages 333-342

  Chen, Jun ^a   Deng, Fan ^a   Li, Jun ^a   Wang, Q Jane ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

C1 domain; Diacylglycerol; Ligand binding affinity; Phorbol esters; Protein kinase D (PKD); Selectivity

Indexed keywords

BINDING ENERGY; GLYCEROL; PROTEINS;

C1 DOMAIN; DIACYLGLYCEROL; LIGAND-BINDING AFFINITY; PHORBOL ESTERS; PROTEIN KINASE D (PKD);

ESTERS;

DIOCTANOIN; LYSINE; PHORBOL DIBUTYRATE; POLYCYSTIN 1; POLYCYSTIN 2; PROTEIN KINASE D; DIACYLGLYCEROL; ISOENZYME; LIGAND; PHORBOL ESTER; PROTEIN KINASE C;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG BINDING; HYDROPHOBICITY; LIGAND BINDING; MEMBRANE TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS; AMINO ACID SEQUENCE; ANIMAL; CELL MEMBRANE; CHEMISTRY; CLASSIFICATION; DRUG EFFECT; ENZYME ACTIVATION; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; MOUSE; MUTATION; NUCLEOTIDE SEQUENCE; PROTEIN BINDING; PROTEIN TRANSPORT; SEQUENCE ALIGNMENT;

AMINO ACID SEQUENCE; ANIMALS; CELL MEMBRANE; CONSERVED SEQUENCE; DIGLYCERIDES; ENZYME ACTIVATION; HUMANS; ISOENZYMES; LIGANDS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; PHORBOL ESTERS; PROTEIN BINDING; PROTEIN KINASE C; PROTEIN TRANSPORT; SEQUENCE ALIGNMENT;

EID: 42449091192     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20071334     Document Type: Article

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