Coupling factor 6-induced activation of ecto-F 1F o complex induces insulin resistance, mild glucose intolerance and elevated blood pressure in mice

Diabetologia

Volumn 55, Issue 2, 2012, Pages 520-529

  Osanai, T ^a   Tanaka, M ^a   Magota, K ^b   Tomita, H ^a   Okumura, K ^a  

^a HIROSAKI UNIVERSITY   (Japan)

^b DAIICHI SANKYO CO   (Japan)

Author keywords

Coupling factor 6; Diabetes; Ecto F 1F o complex; Hypertension; Transgenic mouse

Indexed keywords

ADENOSINE TRIPHOSPHATASE; COUPLING FACTOR 6 PROTEIN; GLUCOSE TRANSPORTER 4; INSULIN RECEPTOR; INSULIN RECEPTOR BETA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN AKT1; PROTEIN KINASE B; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; RAC1 PROTEIN; UNCLASSIFIED DRUG;

ACIDOSIS; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PH; CONTROLLED STUDY; COUPLING FACTOR 6 GENE; DIABETES MELLITUS; DISEASE ASSOCIATION; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME SYNTHESIS; GENE; GENE OVEREXPRESSION; GLUCONEOGENESIS; GLUCOSE INTOLERANCE; HYPERTENSION; INSULIN RESISTANCE; INTRACELLULAR MEMBRANE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SKELETAL MUSCLE; TRANSGENIC MOUSE;

ACIDOSIS; ANIMALS; BLOOD PRESSURE; CYTOPLASM; DISEASE MODELS, ANIMAL; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; HEPATOCYTES; HUMANS; HYDROGEN-ION CONCENTRATION; HYPERTENSION; INSULIN RESISTANCE; MICE; MICE, TRANSGENIC; MITOCHONDRIAL PROTON-TRANSLOCATING ATPASES; NEUROPEPTIDES; OXIDATIVE PHOSPHORYLATION COUPLING FACTORS; PROTON-TRANSLOCATING ATPASES; RAC GTP-BINDING PROTEINS; RAC1 GTP-BINDING PROTEIN;

EID: 84856699851     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-011-2341-z     Document Type: Article

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