Extracellular acidosis results in higher intracellular acidosis and greater contraction in spontaneously hypertensive rat aorta

European Journal of Pharmacology

Volumn 465, Issue 1-2, 2003, Pages 141-144

  Rohra, Dileep Kumar ^a   Saito, Shin Ya ^a   Ohizumi, Yasushi ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

Acidic; Acidosis; Aorta; Intracellular; PH; Spontaneously hypertensive rat (SHR); Wistar Kyoto rat (WKY)

Indexed keywords

ACIDITY; ACIDOSIS; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; AORTA; AORTA CONSTRICTION; ARTICLE; CELL PH; CONTROLLED STUDY; CORRELATION ANALYSIS; ESSENTIAL HYPERTENSION; EXTRACELLULAR SPACE; HEART MUSCLE CONTRACTILITY; INTRACELLULAR SPACE; MALE; NONHUMAN; PH; PH MEASUREMENT; PRIORITY JOURNAL; RAT; SPONTANEOUSLY HYPERTENSIVE RAT;

EID: 0037470767     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(03)01490-0     Document Type: Article

References (19)

1. + channels in resting state of femoral arteries from spontaneously rats at prehypertensive stage. J. Pharmacol. Exp. Ther. 275:1995;775-783.
2. + and functional consequences in vascular smooth muscle. Circ. Res. 86:2000;355-363.
3. +-induced swine carotid artery contraction. Hypertension. 25:1995;482-489.
4. Chipperfield A.R., Harper A.A. Chloride in smooth muscle. Prog. Biophys. Mol. Biol. 74:2000;175-221.
5. 3 anion exchanger in erythrocytes of patients with essential hypertension. J. Hypertens. 10:1992;579-585.
6. + exchanger activity and NHE-1 mRNA expression in lymphocytes from patients with essential hypertension. Hypertension. 25:1995;356-364.
7. Izzard A.S., Heagerty A.M. Resting intracellular pH in mesenteric resistance arteries from spontaneously hypertensive and Wistar-Kyoto rats: effects of amiloride and 4,4′-diisothiocyanatostilbene-2,2′-disulphonic acid. J. Hypertens. 6:1989;S128-S129.
8. Jaiswal N., Jaiswal R.K., Tallant E.A., Diz D.I., Ferrario C.M. Alterations in prostaglandin production in spontaneously hypertensive rat smooth muscle cells. Hypertension. 21:1993;900-905.
9. - exchange in Madin-Darby canine kidney cells. Role in intracellular pH regulation. J. Biol. Chem. 262:1987;4516-4520.
10. LaPointe M.S., Ye M., Bacallao R., Batlle D. NHE-1 protein in vascular smooth muscle and lymphocytes from the spontaneously hypertensive rat. Hypertension. 30:1997;880-885.
11. 2+-ATPase and alpha-smooth muscle actin gene expression in aortas of normotensive and spontaneously hypertensive rats. Circ. Res. 72:1993;341-348.
12. i in porcine coronary artery smooth muscle. Circ. Res. 75:1994;990-998.
13. --dependent mechanism. Circ. Res. 67:1990;814-825.
14. - channels in acidic pH-induced contraction of the aorta of spontaneously hypertensive and Wistar Kyoto rats. Eur. J. Pharmacol. 453:2002;279-286.
15. Rohra D.K., Yamakuni T., Furukawa K.-I., Ishii N., Shinkawa T., Isobe T., Ohizumi Y. Stimulated tyrosine phosphorylation of phosphatidylinositol 3-kinase causes acidic pH-induced contraction in spontaneously hypertensive rat aorta. J. Pharmacol. Exp. Ther. 303:2002;1255-1264.
16. Rosskopf D., Düsing R., Siffert W. Membrane sodium-proton exchange and primary hypertension. Hypertension. 21:1993;607-617.
17. + exchange in pulmonary artery smooth muscle from spontaneously hypertensive and Wistar-Kyoto rats. Am. J. Physiol. 269:1995;L673-L680.
18. Smith G.L., Austin C., Crichton C., Wray S. A review of the actions and control of intracellular pH in vascular smooth muscle. Cardiovasc. Res. 38:1998;316-331.
19. Wray S. Smooth muscle intracellular pH: measurement, regulation, and function. Am. J. Physiol. 254:1988;C213-C225.