Development of a Chip/Chip/SRM platform using digital chip isoelectric focusing and LC-Chip mass spectrometry for enrichment and quantitation of low abundance protein biomarkers in human plasma

Journal of Proteome Research

Volumn 11, Issue 2, 2012, Pages 808-817

  Rafalko, Agnes ^a   Dai, Shujia ^a   Hancock, William S ^a   Karger, Barry L ^a   Hincapie, Marina ^a  

^a NORTHEASTERN UNIVERSITY   (United States)

Author keywords

digital ProteomeChip; dPC; IEF; isoelectric focusing; LC Chip; prostate specific antigen; PSA; QQQ; selected reactionmonitoring; SRM

Indexed keywords

ALBUMIN; IMMUNOGLOBULIN G; PROSTATE SPECIFIC ANTIGEN;

ARTICLE; ASSAY; COHORT ANALYSIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIGITAL PROTEOME CHIP; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; ISOELECTRIC FOCUSING; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY SELECTED REACTION MONITORING MASS SPECTROMETRY; MALE; MASS SPECTROMETRY; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN ANALYSIS; SELECTED REACTION MONITORING ASSAY;

AMINO ACID SEQUENCE; ANIMALS; BIOLOGICAL MARKERS; BLOOD PROTEINS; CATTLE; CHROMATOGRAPHY, LIQUID; FEMALE; HUMANS; IMMUNOSORBENT TECHNIQUES; ISOELECTRIC FOCUSING; LIMIT OF DETECTION; LINEAR MODELS; MALE; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROSTATE-SPECIFIC ANTIGEN; PROTEIN ARRAY ANALYSIS; PROTEOMICS; REPRODUCIBILITY OF RESULTS; TRYPSIN;

EID: 84856688004     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr2006704     Document Type: Article

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