메뉴 건너뛰기




Volumn 302, Issue 4, 2012, Pages

Multiparity leads to obesity and inflammation in mothers and obesity in male offspring

Author keywords

Coactivator 1 ; Developmental programming; Diabetes; Peroxisome proliferator activated receptor

Indexed keywords

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE;

EID: 84856602820     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00487.2011     Document Type: Article
Times cited : (43)

References (74)
  • 1
    • 75149175657 scopus 로고    scopus 로고
    • Grand multiparity is associated with type 2 diabetes in Filipino American women, independent of visceral fat and adiponectin
    • Araneta MR, Barrett-Connor E. Grand multiparity is associated with type 2 diabetes in Filipino American women, independent of visceral fat and adiponectin. Diabetes Care 33: 385-389, 2010.
    • (2010) Diabetes Care , vol.33 , pp. 385-389
    • Araneta, M.R.1    Barrett-Connor, E.2
  • 2
    • 43049127871 scopus 로고    scopus 로고
    • Developmental origins of obesity and the metabolic syndrome: The role of maternal obesity
    • In:, edited by Korbontis M. Basel, Switzerland: Kerger
    • Armitage JA, Poston L, Taylor PD. Developmental origins of obesity and the metabolic syndrome: The role of maternal obesity. In: Frontiers of Hormone Research, Obesity and Metabolism, edited by Korbontis M. Basel, Switzerland: Kerger, 2008, p. 73-84.
    • (2008) Frontiers of Hormone Research, Obesity and Metabolism , pp. 73-84
    • Armitage, J.A.1    Poston, L.2    Taylor, P.D.3
  • 4
    • 47249100701 scopus 로고    scopus 로고
    • Offspring from mothers fed a 'junk food' diet in pregnancy and lactation exhibit exacerbated adiposity that is more pronounced in females
    • Bayol SA, Simbi BH, Bertrand JA, Strickland NC. Offspring from mothers fed a 'junk food' diet in pregnancy and lactation exhibit exacerbated adiposity that is more pronounced in females. J Physiol 586: 3219-3230, 2008.
    • (2008) J Physiol , vol.586 , pp. 3219-3230
    • Bayol, S.A.1    Simbi, B.H.2    Bertrand, J.A.3    Strickland, N.C.4
  • 6
    • 0016586870 scopus 로고
    • A manual colorimetric assay of triglycerides in serum
    • Biggs HG, Erikson JM, Moorehead WR. A manual colorimetric assay of triglycerides in serum. Clin Chem 21: 437-441, 1975.
    • (1975) Clin Chem , vol.21 , pp. 437-441
    • Biggs, H.G.1    Erikson, J.M.2    Moorehead, W.R.3
  • 7
    • 80052050501 scopus 로고    scopus 로고
    • Maternal obesity during gestation impairs fatty acid oxidation and mitochondrial sirt3 expression in rat offspring at weaning
    • Borengasser SJ, Lau F, Kang P, Blackburn ML, Ronis MJ, Badger TM, Shankar K. Maternal obesity during gestation impairs fatty acid oxidation and mitochondrial sirt3 expression in rat offspring at weaning. PLoS One 6: e24068, 2011.
    • (2011) PLoS One , vol.6
    • Borengasser, S.J.1    Lau, F.2    Kang, P.3    Blackburn, M.L.4    Ronis, M.J.5    Badger, T.M.6    Shankar, K.7
  • 8
    • 0042885745 scopus 로고    scopus 로고
    • Obesity and pregnancy-the propagation of a viscous cycle?
    • Catalano PM. Obesity and pregnancy-the propagation of a viscous cycle? J Clin Endocrinol Metab 88: 3505-3506, 2003.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 3505-3506
    • Catalano, P.M.1
  • 9
    • 33748754174 scopus 로고    scopus 로고
    • The short-and long-term implications of maternal obesity on the mother and her offspring
    • Catalano PM, Ehrenberg HM. The short-and long-term implications of maternal obesity on the mother and her offspring. BJOG 113: 1126-1133, 2006.
    • (2006) BJOG , vol.113 , pp. 1126-1133
    • Catalano, P.M.1    Ehrenberg, H.M.2
  • 12
    • 59049094902 scopus 로고    scopus 로고
    • Racial, ethnic, and socioeconomic differences in the incidence of obesity related to childbirth
    • Davis EM, Zyzanski SJ, Olson CM, Stange KC, Horwitz RI. Racial, ethnic, and socioeconomic differences in the incidence of obesity related to childbirth. Am J Public Health 99: 294-299, 2009.
    • (2009) Am J Public Health , vol.99 , pp. 294-299
    • Davis, E.M.1    Zyzanski, S.J.2    Olson, C.M.3    Stange, K.C.4    Horwitz, R.I.5
  • 14
    • 77955981879 scopus 로고    scopus 로고
    • Placental amino acid transport and placental leptin resistance in pregnancies complicated by maternal obesity
    • Farley DM, Choi J, Dudley DJ, Li C, Jenkins SL, Myatt L, Nathanielsz PS. Placental amino acid transport and placental leptin resistance in pregnancies complicated by maternal obesity. Placenta 31: 713-724, 2010.
    • (2010) Placenta , vol.31 , pp. 713-724
    • Farley, D.M.1    Choi, J.2    Dudley, D.J.3    Li, C.4    Jenkins, S.L.5    Myatt, L.6    Nathanielsz, P.S.7
  • 15
    • 79953210362 scopus 로고    scopus 로고
    • Regulation of PGC-1_, a nodal regulator of mitochondrial biogenesis
    • Fernandez-Marcos PJ, Auxerx J. Regulation of PGC-1_, a nodal regulator of mitochondrial biogenesis. Am J Clin Nutr 93: 884S-890S, 2011.
    • (2011) Am J Clin Nutr , vol.93
    • Fernandez-Marcos, P.J.1    Auxerx, J.2
  • 18
    • 33644856005 scopus 로고    scopus 로고
    • Obesity and the role of adipose tissue in inflammation and metabolism
    • Greenberg AS, Obin MS. Obesity and the role of adipose tissue in inflammation and metabolism. Am J Clin Nutr 83: 461S-465S, 2006.
    • (2006) Am J Clin Nutr , vol.83
    • Greenberg, A.S.1    Obin, M.S.2
  • 19
    • 0034957332 scopus 로고    scopus 로고
    • Does the pattern of postpartum weight change differ according to pregravid body size?
    • Gunderson EP, Abrams B, Selvin S. Does the pattern of postpartum weight change differ according to pregravid body size? Int J Obes Relat Metab Disord 25: 853-862, 2001.
    • (2001) Int J Obes Relat Metab Disord , vol.25 , pp. 853-862
    • Gunderson, E.P.1    Abrams, B.2    Selvin, S.3
  • 20
    • 67651122887 scopus 로고    scopus 로고
    • Childbearing is associated with higher incidence of the metabolic syndrome among women of reproductive age controlling for measurements before pregnancy: The CARDIA study
    • Gunderson EP, Jacobs DR Jr, Chiang V, Lewis CE, Tsai A, Quesenberry CP Jr, Sidney S. Childbearing is associated with higher incidence of the metabolic syndrome among women of reproductive age controlling for measurements before pregnancy: the CARDIA study. Am J Obstet Gynecol 201: 177. e1-177. e9, 2009.
    • (2009) Am J Obstet Gynecol , vol.201
    • Gunderson, E.P.1    Jacobs Jr., D.R.2    Chiang, V.3    Lewis, C.E.4    Tsai, A.5    Quesenberry Jr., C.P.6    Sidney, S.7
  • 21
    • 33845596500 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism
    • Handschin C, Speigelman BM. Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism. Endocr Rev 27: 728-735, 2006.
    • (2006) Endocr Rev , vol.27 , pp. 728-735
    • Handschin, C.1    Speigelman, B.M.2
  • 22
    • 33745470336 scopus 로고    scopus 로고
    • The placenta cytokine network and inflammatory signals
    • Hauguel-de Mouzon S, Guerre-Millo M. The placenta cytokine network and inflammatory signals. Placenta 27: 794-798, 2006.
    • (2006) Placenta , vol.27 , pp. 794-798
    • Hauguel-de Mouzon, S.1    Guerre-Millo, M.2
  • 25
    • 67651159365 scopus 로고    scopus 로고
    • Transcriptional control of mitochondrial biogenesis and function
    • Hock MB, Kralli A. Transcriptional control of mitochondrial biogenesis and function. Annu Rev Physiol 71: 177-203, 2009.
    • (2009) Annu Rev Physiol , vol.71 , pp. 177-203
    • Hock, M.B.1    Kralli, A.2
  • 26
    • 77649188000 scopus 로고    scopus 로고
    • Obesity in pregnancy: Prevalence and metabolic consequences
    • Huda SS, Brodie LE, Sattar N. Obesity in pregnancy: prevalence and metabolic consequences. Semin Fetal Neonatal Med 15: 70-76, 2010.
    • (2010) Semin Fetal Neonatal Med , vol.15 , pp. 70-76
    • Huda, S.S.1    Brodie, L.E.2    Sattar, N.3
  • 29
    • 34250902914 scopus 로고    scopus 로고
    • Role of the placenta in fetal programming: Underlying mechanisms and potential interventional approaches
    • Jansson T, Powell TL. Role of the placenta in fetal programming: underlying mechanisms and potential interventional approaches. Clin Sci (Lond) 113: 1-13, 2007.
    • (2007) Clin Sci (Lond) , vol.113 , pp. 1-13
    • Jansson, T.1    Powell, T.L.2
  • 30
    • 77954944956 scopus 로고    scopus 로고
    • Lipotoxicity in obese pregnancy and its potential role in adverse pregnancy outcome and obesity in the offspring
    • Jarvie E, Hauguel-de-Mouzon S, Nelson SM, Sattar N, Catalano PM, Freeman DJ. Lipotoxicity in obese pregnancy and its potential role in adverse pregnancy outcome and obesity in the offspring. Clin Sci (Lond) 119: 123-129, 2010.
    • (2010) Clin Sci (Lond) , vol.119 , pp. 123-129
    • Jarvie, E.1    Hauguel-de-Mouzon, S.2    Nelson, S.M.3    Sattar, N.4    Catalano, P.M.5    Freeman, D.J.6
  • 31
    • 77349117770 scopus 로고    scopus 로고
    • Obstetric management of obesity in pregnancy
    • Jarvie E, Ramsay JE. Obstetric management of obesity in pregnancy. Semin Fetal Neonatal Med 15: 83-88, 2010.
    • (2010) Semin Fetal Neonatal Med , vol.15 , pp. 83-88
    • Jarvie, E.1    Ramsay, J.E.2
  • 32
    • 70449623354 scopus 로고    scopus 로고
    • IL-6 stimulates system A amino acid transporter activity in trophoblast cells through STAT3 and increased expression of SNAT2
    • Jones HN, Jansson T, Powell TL. IL-6 stimulates system A amino acid transporter activity in trophoblast cells through STAT3 and increased expression of SNAT2. Am J Physiol Cell Physiol 297: C1228-C1235, 2009.
    • (2009) Am J Physiol Cell Physiol , vol.297
    • Jones, H.N.1    Jansson, T.2    Powell, T.L.3
  • 33
    • 58249102098 scopus 로고    scopus 로고
    • High-fat diet before and during pregnancy causes marked up-regulation of placental nutrient transport and fetal overgrowth in C57/BL6 mice
    • Jones HN, Woollett LA, Barbour N, Prasad PD, Powell TL, Jansson T. High-fat diet before and during pregnancy causes marked up-regulation of placental nutrient transport and fetal overgrowth in C57/BL6 mice. FASEB J 23: 271-278, 2009.
    • (2009) FASEB J , vol.23 , pp. 271-278
    • Jones, H.N.1    Woollett, L.A.2    Barbour, N.3    Prasad, P.D.4    Powell, T.L.5    Jansson, T.6
  • 36
    • 75749148425 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis: Transition from theory to practice
    • Libby P, Okamoto Y, Rocha VZ, Folco E. Inflammation in atherosclerosis: transition from theory to practice. Circ J 74: 213-220, 2010.
    • (2010) Circ J , vol.74 , pp. 213-220
    • Libby, P.1    Okamoto, Y.2    Rocha, V.Z.3    Folco, E.4
  • 38
    • 79953186142 scopus 로고    scopus 로고
    • PGC-1 coactivators in the control of energy metabolism
    • Liu C, Lin JD. PGC-1 coactivators in the control of energy metabolism. Acta Biochim Biophys Sin (Shanghai) 43: 248-257, 2011.
    • (2011) Acta Biochim Biophys Sin (Shanghai) , vol.43 , pp. 248-257
    • Liu, C.1    Lin, J.D.2
  • 40
    • 59649130350 scopus 로고    scopus 로고
    • Metabolic profiling of PPARalpha-/-mice reveals defects in carnitine and amino acid homeostasis that are partially reversed by oral carnitine supplementation
    • Makowski L, Noland RC, Koves TR, Xing W, Ilkayeva OR, Muehlbauer MJ, Stevens RD, Muoio DM. Metabolic profiling of PPARalpha-/-mice reveals defects in carnitine and amino acid homeostasis that are partially reversed by oral carnitine supplementation. FASEB J 23: 586-604, 2009.
    • (2009) FASEB J , vol.23 , pp. 586-604
    • Makowski, L.1    Noland, R.C.2    Koves, T.R.3    Xing, W.4    Ilkayeva, O.R.5    Muehlbauer, M.J.6    Stevens, R.D.7    Muoio, D.M.8
  • 41
    • 0034068935 scopus 로고    scopus 로고
    • Maternal high density lipoproteins affect fetal mass and extra-embryonic fetal tissue sterol metabolism in the mouse
    • McConihay JA, Honkomp AM, Granholm NA, Woollett LA. Maternal high density lipoproteins affect fetal mass and extra-embryonic fetal tissue sterol metabolism in the mouse. J Lipid Res 41: 424-432, 2000.
    • (2000) J Lipid Res , vol.41 , pp. 424-432
    • McConihay, J.A.1    Honkomp, A.M.2    Granholm, N.A.3    Woollett, L.A.4
  • 45
    • 67349223615 scopus 로고    scopus 로고
    • Established diet-induced obesity in female rats leads to offspring hyperphagia, adiposity and insulin resistance
    • Nivoit P, Morens C, Van Assche FA, Jansen E, Poston L, Remacle C, Reusens B. Established diet-induced obesity in female rats leads to offspring hyperphagia, adiposity and insulin resistance. Diabetologia 52: 1133-1142, 2009.
    • (2009) Diabetologia , vol.52 , pp. 1133-1142
    • Nivoit, P.1    Morens, C.2    van Assche, F.A.3    Jansen, E.4    Poston, L.5    Remacle, C.6    Reusens, B.7
  • 46
    • 79961090457 scopus 로고    scopus 로고
    • Effect of prepregnancy maternal overweight and obesity on pregnancy outcome
    • Ovesen P, Rasmussen S, Kesmodel U. Effect of prepregnancy maternal overweight and obesity on pregnancy outcome. Obstet Gynecol 118: 305-312, 2011.
    • (2011) Obstet Gynecol , vol.118 , pp. 305-312
    • Ovesen, P.1    Rasmussen, S.2    Kesmodel, U.3
  • 47
    • 45549097738 scopus 로고    scopus 로고
    • Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1
    • Park JH, Stoffers DA, Nicholls RD, Simmons RA. Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1. J Clin Invest 118: 2316-2324, 2008.
    • (2008) J Clin Invest , vol.118 , pp. 2316-2324
    • Park, J.H.1    Stoffers, D.A.2    Nicholls, R.D.3    Simmons, R.A.4
  • 48
    • 0035908632 scopus 로고    scopus 로고
    • C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus
    • Pradhan AD, Manson JE, Rifai N, Buring JE, Ridker PM. C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus. JAMA 286: 327-334, 2001.
    • (2001) JAMA , vol.286 , pp. 327-334
    • Pradhan, A.D.1    Manson, J.E.2    Rifai, N.3    Buring, J.E.4    Ridker, P.M.5
  • 50
    • 39749145196 scopus 로고    scopus 로고
    • Translating molecular discoveries into new therapies for atherosclerosis
    • Rader DJ, Daugherty A. Translating molecular discoveries into new therapies for atherosclerosis. Nature 451: 904-913, 2008.
    • (2008) Nature , vol.451 , pp. 904-913
    • Rader, D.J.1    Daugherty, A.2
  • 53
    • 0036338165 scopus 로고    scopus 로고
    • Excess pregnancy weight gain and long-term obesity: One decade later
    • Rooney BL, Schauberger CW. Excess pregnancy weight gain and long-term obesity: one decade later. Obstet Gynecol 100: 245-252, 2002.
    • (2002) Obstet Gynecol , vol.100 , pp. 245-252
    • Rooney, B.L.1    Schauberger, C.W.2
  • 54
    • 27944461454 scopus 로고    scopus 로고
    • Impact of perinatal weight change on long-term obesity and obesity-related illnesses
    • Rooney BL, Schauberger CW, Mathiason MA. Impact of perinatal weight change on long-term obesity and obesity-related illnesses. Obstet Gynecol 106: 1349-1356, 2005.
    • (2005) Obstet Gynecol , vol.106 , pp. 1349-1356
    • Rooney, B.L.1    Schauberger, C.W.2    Mathiason, M.A.3
  • 55
    • 77953518974 scopus 로고    scopus 로고
    • Maternal obesity: The interplay between inflammation, mother and fetus
    • Schmatz M, Madan J, Marino T, Davis J. Maternal obesity: the interplay between inflammation, mother and fetus. J Perinatol 30: 441-446, 2009.
    • (2009) J Perinatol , vol.30 , pp. 441-446
    • Schmatz, M.1    Madan, J.2    Marino, T.3    Davis, J.4
  • 56
    • 77951126550 scopus 로고    scopus 로고
    • Regulatory enzymes of mitochondrial beta-oxidation as targets for treatment of the metabolic syndrome
    • Schreurs M, Kupers F, van der Leij FR. Regulatory enzymes of mitochondrial beta-oxidation as targets for treatment of the metabolic syndrome. Obes Res 11: 380-388, 2010.
    • (2010) Obes Res , vol.11 , pp. 380-388
    • Schreurs, M.1    Kupers, F.2    van der Leij, F.R.3
  • 58
    • 78649568544 scopus 로고    scopus 로고
    • Epigenetic regulation of insulin resistance in nonalcoholic fatty liver disease: Impact of liver methylation of the peroxisome proliferator-activated receptor coactivator 1 promoter
    • Sookoian S, Rosselli MS, Gemma C, Burgueño AL, Fernández Gianotti T, Castaño GO, Pirola CJ. Epigenetic regulation of insulin resistance in nonalcoholic fatty liver disease: impact of liver methylation of the peroxisome proliferator-activated receptor coactivator 1 promoter. Hepatology 52: 1992-2000, 2010.
    • (2010) Hepatology , vol.52 , pp. 1992-2000
    • Sookoian, S.1    Rosselli, M.S.2    Gemma, C.3    Burgueño, A.L.4    Fernández Gianotti, T.5    Castaño, G.O.6    Pirola, C.J.7
  • 59
    • 33947501003 scopus 로고    scopus 로고
    • Longitudinal assessment of maternal endothelial function and markers of inflammation and placental function throughout pregnancy in lean and obese mothers
    • Stewart FM, Freeman DJ, Ramsay JE, Greer IA, Caslake M, Ferrell WR. Longitudinal assessment of maternal endothelial function and markers of inflammation and placental function throughout pregnancy in lean and obese mothers. J Clin Endocrinol Metab 92: 969-975, 2007.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 969-975
    • Stewart, F.M.1    Freeman, D.J.2    Ramsay, J.E.3    Greer, I.A.4    Caslake, M.5    Ferrell, W.R.6
  • 60
    • 77958453583 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor {gamma} coactivator 1 {alpha} (PGC-1{alpha}) promotes skeletal muscle lipid refueling in vivo by activating de novo lipogenesis and the pentose phosphate pathway
    • Summermatter S, Baum O, Santos G, Hoppeler H, Handschin C. Peroxisome proliferator-activated receptor {gamma} coactivator 1 {alpha} (PGC-1{alpha}) promotes skeletal muscle lipid refueling in vivo by activating de novo lipogenesis and the pentose phosphate pathway. J Biol Chem 285: 32793-32800, 2010.
    • (2010) J Biol Chem , vol.285 , pp. 32793-32800
    • Summermatter, S.1    Baum, O.2    Santos, G.3    Hoppeler, H.4    Handschin, C.5
  • 63
    • 0028157731 scopus 로고
    • Reevaluation and application of the dual-isotope plasma ratio method for the measurement of intestinal cholesterol absorption in the hamster
    • Turley SD, Herndon MW, Dietschy JM. Reevaluation and application of the dual-isotope plasma ratio method for the measurement of intestinal cholesterol absorption in the hamster. J Lipid Res 35: 328-339, 1994.
    • (1994) J Lipid Res , vol.35 , pp. 328-339
    • Turley, S.D.1    Herndon, M.W.2    Dietschy, J.M.3
  • 64
    • 46749125376 scopus 로고    scopus 로고
    • Transcriptional control of mitochondrial biogenesis: The central role of PGC-1alpha
    • Ventura-Clapier R, Garnier A, Veksler V. Transcriptional control of mitochondrial biogenesis: the central role of PGC-1alpha. Cardiovasc Res 79: 208-217, 2008.
    • (2008) Cardiovasc Res , vol.79 , pp. 208-217
    • Ventura-Clapier, R.1    Garnier, A.2    Veksler, V.3
  • 65
    • 35548941189 scopus 로고    scopus 로고
    • Epigenetic epidemiology of the developmental origins hypothesis
    • Waterland RA, Michels KB. Epigenetic epidemiology of the developmental origins hypothesis. Annu Rev Nutr 27: 363-388, 2007.
    • (2007) Annu Rev Nutr , vol.27 , pp. 363-388
    • Waterland, R.A.1    Michels, K.B.2
  • 66
    • 18244370762 scopus 로고    scopus 로고
    • Inflammation, stress, and diabetes
    • Wellen KE, Hotamisligil GS. Inflammation, stress, and diabetes. J Clin Invest 115: 1111-1119, 2005.
    • (2005) J Clin Invest , vol.115 , pp. 1111-1119
    • Wellen, K.E.1    Hotamisligil, G.S.2
  • 68
    • 36849089066 scopus 로고    scopus 로고
    • Inability to fully suppress sterol synthesis rates with exogenous sterol in embryonic and extraembyronic fetal tissues
    • Yao L, Jenkins K, Horn PS, Lichtenberg MH, Woollett LA. Inability to fully suppress sterol synthesis rates with exogenous sterol in embryonic and extraembyronic fetal tissues. Biochim Biophys Acta 1171: 1372-1379, 2007.
    • (2007) Biochim Biophys Acta , vol.1171 , pp. 1372-1379
    • Yao, L.1    Jenkins, K.2    Horn, P.S.3    Lichtenberg, M.H.4    Woollett, L.A.5
  • 70
    • 67651102871 scopus 로고    scopus 로고
    • The role of PPARalpha in lipid metabolism and obesity: Focusing on the effects of estrogen on PPARalpha actions
    • Yoon M. The role of PPARalpha in lipid metabolism and obesity: focusing on the effects of estrogen on PPARalpha actions. Pharmacol Res 60: 151-159, 2009.
    • (2009) Pharmacol Res , vol.60 , pp. 151-159
    • Yoon, M.1
  • 71
    • 24144496133 scopus 로고    scopus 로고
    • Role of adiponectin in the protective action of dietary saturated fat against alcoholic fatty liver in mice
    • You M, Considine RV, Leone TC, Kelly DP, Crabb DW. Role of adiponectin in the protective action of dietary saturated fat against alcoholic fatty liver in mice. Hepatology 42: 568-577, 2005.
    • (2005) Hepatology , vol.42 , pp. 568-577
    • You, M.1    Considine, R.V.2    Leone, T.C.3    Kelly, D.P.4    Crabb, D.W.5
  • 72
    • 79551715564 scopus 로고    scopus 로고
    • Epigenetics meets endocrinology
    • Zhang X, Ho SM. Epigenetics meets endocrinology. J Mol Endocrinol 46: R11-R32, 2011.
    • (2011) J Mol Endocrinol , vol.46
    • Zhang, X.1    Ho, S.M.2
  • 73
    • 52949096557 scopus 로고    scopus 로고
    • Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity
    • Zhang X, Zhang G, Zhang H, Karin M, Bai H, Cai D. Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity. Cell 135: 61-73, 2008.
    • (2008) Cell , vol.135 , pp. 61-73
    • Zhang, X.1    Zhang, G.2    Zhang, H.3    Karin, M.4    Bai, H.5    Cai, D.6
  • 74
    • 77951974181 scopus 로고    scopus 로고
    • Maternal obesity upregulates inflammatory signaling pathways and enhances cytokine expression in the mid-gestation sheep placenta
    • Zhu MJ, Du M, Nathanielsz PW, Ford SP. Maternal obesity upregulates inflammatory signaling pathways and enhances cytokine expression in the mid-gestation sheep placenta. Placenta 31: 387-391, 2010.
    • (2010) Placenta , vol.31 , pp. 387-391
    • Zhu, M.J.1    Du, M.2    Nathanielsz, P.W.3    Ford, S.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.