Improved production of erythromycin A by expression of a heterologous gene encoding S-adenosylmethionine synthetase (Applied Microbiology and Biotechnology DOI: 10.1007/s00253-007-0894-z);Improved production of erythromycin a by expression of a heterologous gene encoding S-adenosylmethionine synthetase

Applied Microbiology and Biotechnology

Volumn 75, Issue 4, 2007, Pages 837-842

  Wang, Yong ^a,b   Wang, YiGuang ^a,b   Chu, Ju ^a   Zhuang, Yingping ^a   Zhang, Lixin ^c,d,e,f   Zhang, Siliang ^a  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

^c INSTITUTE OF MICROBIOLOGY   (China)

^d SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY   (China)

^e GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH   (China)

^f SynerZ Pharmaceuticals Inc   (United States)

Author keywords

Erythromycin A; Precision engineering; S adenosylmethionine synthetase; Saccharopolyspora erythraea

Indexed keywords

BIOASSAY; CHROMOSOMES; ENZYMES; GENE ENCODING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ERYTHROMYCIN A; S-ADENOSYLMETHIONINE SYNTHETASE; SACCHAROPOLYSPORA ERYTHRAEA;

DRUG PRODUCTS;

BERYTHROMYCIN; ERYTHROMYCIN; METHIONINE ADENOSYLTRANSFERASE;

BACTERIUM; BIOASSAY; ENZYME; GENE EXPRESSION; RECOMBINATION;

ARTICLE; BACTERIAL GENE; CONTROLLED STUDY; DNA VECTOR; ENZYME SYNTHESIS; GENE EXPRESSION PROFILING; HETEROLOGOUS EXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; SACCHAROPOLYSPORA; SPOROGENESIS; STREPTOMYCES; STREPTOMYCES ERYTHRAEUS; STREPTOMYCES SPECTABILIS;

SACCHAROPOLYSPORA ERYTHRAEA; STREPTOMYCES SPECTABILIS;

EID: 34547487372     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-008-1368-7     Document Type: Erratum

References (17)

1. Bierman M, Logan R, O'Brien K, Seno ET, Ratio RN, Schoner BE (1992) Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp. Gene 116:43-49
2. Brunker P, Minas W, Kallio PT, Bailey JE (1998) Genetic engineering of an industrial strain of Saccharopolyspora erythraea for stable expression of the Vitreoscilla hemoglobin gene (vhb). Microbiology 144:2441-2448
3. Kieser T, Bibb MJ, Buttner MJ, Chater KF, Hopwood DA (2000) Practical streptomyces genetics. The John Innes Foundation, Norwich, UK
4. Kim DJ, Huh JH, Yang YY, Kang CM, Lee IH, Hyun CG, Hong SK, Suh JW (2003) Accumulation of S-adenosyl-l-methionine enhances production of actinorhodin but inhibits sporulation in Streptomyces lividans TK23. J Bacteriol 185:592-600
5. Lee S, Rasheed S (1990) A simple procedure for maximum yield of high-quality plasmid DNA. Biotechniques 9:676-679
6. MacNeil DJ, Occi JL, Gewain KM, MacNeil T, Gibbons PH, Ruby CL, Danis SL (1992) Complex organization of the Streptomyces avermitilis genes encoding the avermectin polyketide synthase. Gene 115:119-125
7. Mazodier P, Petter R, Thompson C (1989) Intergeneric conjugation between Escherichia coli and Streptomyces species. J Bacteriol 171:3583-3585
8. Ochi K, Freese E (1982) A decrease in S-adenosylmethionine synthetase activity increases the probability of spontaneous sporulation. J Bacteriol 152:400-410
9. Okamoto S, Lezhava A, Hosaka T, Okamoto-Hosoya Y, Ochi K (2003) Enhanced expression of S-adenosylmethionine synthetase causes overproduction of actinorhodin in Streptomyces coelicolor A3(2). J Bacteriol 185:601-609
10. Paulus TJ, Tuan JS, Luebke VE, Maine GT, DeWitt JP, Katz L (1990) Mutation and cloning of eryG, the structural gene for erythromycin O-methyltransferase from Saccharopolyspora erythraea, and expression of eryG in Escherichia coli. J Bacteriol 172(5):2541-2546
11. Payne SM, Ames BN (1982) A procedure for rapid extraction and high-pressure liquid chromatographic separation of the nucleotides and other small molecules from bacterial cells. Anal Biochem 123:151-161
12. Sambrook J, Russell DW (2001) Molecular cloning: a laboratory manual, 3rd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
13. Shin SK, Xu D, Kwon HJ, Suh JW (2006) S-adenosylmethionine activates adpA transcription and promotes streptomycin biosynthesis in Streptomyces griseus. FEMS Microbiol Lett 259:53-59
14. Stassi D, Donadio S, Staver MJ, Katz L (1993) Identification of a Saccharopolyspora erythraea gene required for the final hydroxylation step in erythromycin biosynthesis. J Bacteriol 175:182-189
15. Tsuji K, Goetz JF (1978) HPLC as a rapid means of monitoring erythromycin and tetracycline fermentation processes. J Antibiot (Tokyo) 31:302-308
16. Vara J, Lewandowska-Skarbek M, Wang YG, Donadio S, Hutchinson CR (1989) Cloning of genes governing the deoxysugar portion of the erythromycin biosynthesis pathway in Saccharopolyspora erythraea (Streptomyces erythreus). J Bacteriol 171:5872-5881
17. Wang YG (1984) Possible role of plasmids in erythromycin producing strain Str. Erythreus NRRL 2338. Acta Microbiol Sin 24:357-362