메뉴 건너뛰기




Volumn 14, Issue 4, 1998, Pages 561-566

Improved erythromycin production in a genetically engineered industrial strain of Saccharopolyspora erythraea

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC PRODUCTION; BIOSYNTHESIS; FERMENTATION; GENETIC ENGINEERING; HEMOGLOBIN;

EID: 0032128237     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1021/bp980055t     Document Type: Article
Times cited : (73)

References (34)
  • 2
    • 0028206430 scopus 로고
    • Oxygen transfer efficiency in the biosynthesis of antibiotics in bioreactors with a modified Rushton turbine agitator
    • Roman, R. V.; Gavrilescu, M. Oxygen transfer efficiency in the biosynthesis of antibiotics in bioreactors with a modified Rushton turbine agitator. Acta Biotechnol. 1994, 14, 181-192.
    • (1994) Acta Biotechnol , vol.14 , pp. 181-192
    • Roman, R.V.1    Gavrilescu, M.2
  • 3
    • 0023817336 scopus 로고
    • Structure and function of bacterial hemoglobin and related proteins
    • Webster, D. A. Structure and function of bacterial hemoglobin and related proteins. Adv. Org. Biochem. 1988, 7, 245-265.
    • (1988) Adv. Org. Biochem. , vol.7 , pp. 245-265
    • Webster, D.A.1
  • 4
    • 0022486777 scopus 로고
    • Primary sequence of a dimeric bacterial haemoglobin from Vitreoscilla
    • Wakabayashi, S.; Matsubara, H.; Webster, D. A. Primary sequence of a dimeric bacterial haemoglobin from Vitreoscilla. Nature 1986, 322, 481-483.
    • (1986) Nature , vol.322 , pp. 481-483
    • Wakabayashi, S.1    Matsubara, H.2    Webster, D.A.3
  • 5
    • 0023874286 scopus 로고
    • Heterologous expression of a bacterial haemoglobin improves the growth properties of recombinant Escherichia coli
    • Khosla, C.; Bailey, J. E. Heterologous expression of a bacterial haemoglobin improves the growth properties of recombinant Escherichia coli. Nature 1988, 331, 633-635.
    • (1988) Nature , vol.331 , pp. 633-635
    • Khosla, C.1    Bailey, J.E.2
  • 7
    • 0025645664 scopus 로고
    • Presence of bacterial hemoglobin gene improves α-amylase production of a recombinant Escherichia coli strain
    • Khosravi, M.; Webster, D. A.; Stark, B. C. Presence of bacterial hemoglobin gene improves α-amylase production of a recombinant Escherichia coli strain. Plasmid 1990, 24, 190-194.
    • (1990) Plasmid , vol.24 , pp. 190-194
    • Khosravi, M.1    Webster, D.A.2    Stark, B.C.3
  • 8
    • 14744278506 scopus 로고
    • Actinorhodin production by Streptomyces coelicolor and growth of Streptomyces lividans are improved by the expression of a bacterial hemoglobin
    • Magnolo, S. K.; Leenutaphong, D. L.; DeModena, J. A.; Curtis, J. E.; Bailey, J. E.; Galazzo, J. L.; Hughes, D. E. Actinorhodin production by Streptomyces coelicolor and growth of Streptomyces lividans are improved by the expression of a bacterial hemoglobin. Bio/Technology 1991, 9, 473-476.
    • (1991) Bio/Technology , vol.9 , pp. 473-476
    • Magnolo, S.K.1    Leenutaphong, D.L.2    DeModena, J.A.3    Curtis, J.E.4    Bailey, J.E.5    Galazzo, J.L.6    Hughes, D.E.7
  • 9
    • 14744291652 scopus 로고
    • The production of cephalosporin C by Acremonium chrysogenum is improved by the intracellular expression of a bacterial hemoglobin
    • DeModena, J. A.; Gutierrez, S.; Velasco, J.; Fernandez, F. J.; Fachini, R. A.; Galazzo, J. L.; Hughes, D. E.; Martin, J. F. The production of cephalosporin C by Acremonium chrysogenum is improved by the intracellular expression of a bacterial hemoglobin. Bio/Technology 1993, 11, 926-929.
    • (1993) Bio/Technology , vol.11 , pp. 926-929
    • DeModena, J.A.1    Gutierrez, S.2    Velasco, J.3    Fernandez, F.J.4    Fachini, R.A.5    Galazzo, J.L.6    Hughes, D.E.7    Martin, J.F.8
  • 11
    • 0030038319 scopus 로고    scopus 로고
    • Intracellular expression of Vitreoscilla hemoglobin (VHb) enhances total protein Secretion and improves the production of α-amylase and neutral protease in Bacillus subtilis
    • Kallio, P. T.; Bailey, J. E. Intracellular expression of Vitreoscilla hemoglobin (VHb) enhances total protein Secretion and improves the production of α-amylase and neutral protease in Bacillus subtilis. Biotechnol. Prog. 1996, 12, 31-39.
    • (1996) Biotechnol. Prog. , vol.12 , pp. 31-39
    • Kallio, P.T.1    Bailey, J.E.2
  • 12
    • 0030569740 scopus 로고    scopus 로고
    • Genetic engineering to contain the Vitreoscilla hemoglobin gene enhances degradation of benzoic acid by Xanthomonas maltophilia
    • Liu, S.-C.; Webster, D. A.; Wei, M.-L.; Stark, C. Genetic engineering to contain the Vitreoscilla hemoglobin gene enhances degradation of benzoic acid by Xanthomonas maltophilia. Biotechnol. Bioeng. 1996, 49, 101-105.
    • (1996) Biotechnol. Bioeng. , vol.49 , pp. 101-105
    • Liu, S.-C.1    Webster, D.A.2    Wei, M.-L.3    Stark, C.4
  • 13
    • 0028171092 scopus 로고
    • Effect of Vitreoscilla hemoglobin expression on growth and specific tissue plasminogen activator productivity in recombinant Chinese hamster ovary cells
    • Pendse, G. J.; Bailey, J. E. Effect of Vitreoscilla hemoglobin expression on growth and specific tissue plasminogen activator productivity in recombinant Chinese hamster ovary cells. Biotechnol. Bioeng. 1994, 44, 1367-1370.
    • (1994) Biotechnol. Bioeng. , vol.44 , pp. 1367-1370
    • Pendse, G.J.1    Bailey, J.E.2
  • 14
    • 0028430975 scopus 로고
    • Intracellular expression of Vitreoscilla hemoglobin alters the aerobic metabolism of Saccharomyces cerevisiae
    • Chen, W.; Hughes, D. E.; Bailey, J. E. Intracellular expression of Vitreoscilla hemoglobin alters the aerobic metabolism of Saccharomyces cerevisiae. Biotechnol. Prog. 1994, 10, 308-313.
    • (1994) Biotechnol. Prog. , vol.10 , pp. 308-313
    • Chen, W.1    Hughes, D.E.2    Bailey, J.E.3
  • 15
    • 0030890431 scopus 로고    scopus 로고
    • Transgenic tobacco expressing Vitreoscilla hemoglobin exhibits enhanced growth and altered metabolite production
    • Holmberg, N.; Lilius, G.; Bailey, J. E.; Bülow, L. Transgenic tobacco expressing Vitreoscilla hemoglobin exhibits enhanced growth and altered metabolite production. Nat. Biotechnol. 1997, 15, 244-247.
    • (1997) Nat. Biotechnol. , vol.15 , pp. 244-247
    • Holmberg, N.1    Lilius, G.2    Bailey, J.E.3    Bülow, L.4
  • 16
    • 0031665125 scopus 로고    scopus 로고
    • Genetic engineering of an industrial strain of Saccharopolyspora erythraea for stable expression of the Vireoscilla hemoglobin gene (vhb)
    • in press
    • Brünker, P.; Minas, W.; Kallio, P. T.; Bailey, J. E. Genetic engineering of an industrial strain of Saccharopolyspora erythraea for stable expression of the Vireoscilla hemoglobin gene (vhb). Microbiology, in press.
    • Microbiology
    • Brünker, P.1    Minas, W.2    Kallio, P.T.3    Bailey, J.E.4
  • 17
    • 3543020433 scopus 로고
    • Code of Federal Regulations
    • U.S. Government of Printing Office: Washington, DC
    • Code of Federal Regulations. Title 21 - Food and Drugs; U.S. Government of Printing Office: Washington, DC, 1981; pp 247-260.
    • (1981) Title 21 - Food and Drugs , pp. 247-260
  • 20
    • 0017903575 scopus 로고
    • High-performance liquid Chromatographic determination of erythromycin
    • Tsuji, K.; Goetz, J. F. High-performance liquid Chromatographic determination of erythromycin. J. Chromatogr. 1978, 147, 359-367.
    • (1978) J. Chromatogr. , vol.147 , pp. 359-367
    • Tsuji, K.1    Goetz, J.F.2
  • 21
    • 0026245037 scopus 로고
    • Purification and aqueous 2-phase partitioning properties of recombinant Vitreoscilla hemoglobin
    • Hart, R. A.; Bailey, J. E. Purification and aqueous 2-phase partitioning properties of recombinant Vitreoscilla hemoglobin. Enzyme Microb. Technol. 1991, 13, 788-795.
    • (1991) Enzyme Microb. Technol. , vol.13 , pp. 788-795
    • Hart, R.A.1    Bailey, J.E.2
  • 22
    • 0001089022 scopus 로고
    • Western blotting
    • Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A., Struhl, K., Eds.; John Wiley & Sons: New York
    • Winston, S. E.; Fuller, S. A.; Hurrell, J. G. R. Western blotting. In Current Protocols in Molecular Biology; Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A., Struhl, K., Eds.; John Wiley & Sons: New York, 1987; pp 10.8.1-10.8.6.
    • (1987) Current Protocols in Molecular Biology , pp. 1081-1086
    • Winston, S.E.1    Fuller, S.A.2    Hurrell, J.G.R.3
  • 23
    • 0029440479 scopus 로고
    • Macrolides
    • Vining L. C., Stuttard, C., Eds.; Butterworth-Heinemann: Newton, MA
    • Katz, L.; Donadio, S. Macrolides. In Genetics and biochemistry of antibiotic production; Vining L. C., Stuttard, C., Eds.; Butterworth-Heinemann: Newton, MA, 1995; pp 385-420.
    • (1995) Genetics and Biochemistry of Antibiotic Production , pp. 385-420
    • Katz, L.1    Donadio, S.2
  • 24
    • 0025895183 scopus 로고
    • Toward a science of metabolic engineering
    • Bailey, J. E. Toward a science of metabolic engineering. Science 1991, 252, 1668-1675.
    • (1991) Science , vol.252 , pp. 1668-1675
    • Bailey, J.E.1
  • 25
    • 0027416943 scopus 로고
    • Stimulation of erythromycin-A yield by integration of a chromosomal DNA fragment including the eryC1 gene into the chromosome of Saccharopolyspora erythraea
    • Hänel, F.; Schumann, G.; Fiedler, G.; Krügel, H. Stimulation of erythromycin-A yield by integration of a chromosomal DNA fragment including the eryC1 gene into the chromosome of Saccharopolyspora erythraea. Biotechnol. Lett. 1993, 15, 105-110.
    • (1993) Biotechnol. Lett. , vol.15 , pp. 105-110
    • Hänel, F.1    Schumann, G.2    Fiedler, G.3    Krügel, H.4
  • 26
    • 0029078995 scopus 로고
    • The unstable ends of Streptomyces linear chromosomes: A nuisance without cures?
    • Chen, C. W. The unstable ends of Streptomyces linear chromosomes: a nuisance without cures? TIBTECH 1995, 13, 157-160.
    • (1995) TIBTECH , vol.13 , pp. 157-160
    • Chen, C.W.1
  • 27
    • 0027976409 scopus 로고
    • Intracellular expression of Vitreoscilla hemoglobin alters Escherichia coli energy metabolism under oxygen-limited conditions
    • Kallio, P. T.; Kim, D. J.; Tsai, P. S.; Bailey, J. E. Intracellular expression of Vitreoscilla hemoglobin alters Escherichia coli energy metabolism under oxygen-limited conditions. Eur. J. Biochem. 1994, 219, 201-208.
    • (1994) Eur. J. Biochem. , vol.219 , pp. 201-208
    • Kallio, P.T.1    Kim, D.J.2    Tsai, P.S.3    Bailey, J.E.4
  • 28
    • 0029636798 scopus 로고
    • Improvement of Escherichia coli microaerobic oxygen metabolism by Vitreoscilla hemoglobin: New insights from NAD(P)H fluorescence and culture redox potential
    • Tsai, P. S.; Rao, G.; Bailey, J. E. Improvement of Escherichia coli microaerobic oxygen metabolism by Vitreoscilla hemoglobin: New insights from NAD(P)H fluorescence and culture redox potential. Biotechnol. Bioeng. 1995, 47, 347-354.
    • (1995) Biotechnol. Bioeng. , vol.47 , pp. 347-354
    • Tsai, P.S.1    Rao, G.2    Bailey, J.E.3
  • 29
    • 0025820091 scopus 로고
    • Adaptive responses to oxygen limitation in Escherichia coli
    • Spiro, S.; Guest, J. R. Adaptive responses to oxygen limitation in Escherichia coli. Trends Biochem. Sci. 1991, 16, 310-314.
    • (1991) Trends Biochem. Sci. , vol.16 , pp. 310-314
    • Spiro, S.1    Guest, J.R.2
  • 30
    • 0030034536 scopus 로고    scopus 로고
    • Intracellular expression of Vitreoscilla hemoglobin modifies microaerobic Escherichia coli metabolism through elevated concentration and specific activity of cytochrome o
    • Tsai, P. S.; Nägeli, M.; Bailey, J. E. Intracellular expression of Vitreoscilla hemoglobin modifies microaerobic Escherichia coli metabolism through elevated concentration and specific activity of cytochrome o. Biotechnol. Bioeng. 1996, 49, 151-160.
    • (1996) Biotechnol. Bioeng. , vol.49 , pp. 151-160
    • Tsai, P.S.1    Nägeli, M.2    Bailey, J.E.3
  • 31
    • 0029912851 scopus 로고    scopus 로고
    • The effect of culture conditions on the production of erythromycin by Saccharopolyspora erythraea in batch culture
    • Heydarian, S. M.; Lilly M. D.; Ison A. P. The effect of culture conditions on the production of erythromycin by Saccharopolyspora erythraea in batch culture. Biotechnol. Lett. 1996, 18, 1181-1186.
    • (1996) Biotechnol. Lett. , vol.18 , pp. 1181-1186
    • Heydarian, S.M.1    Lilly, M.D.2    Ison, A.P.3
  • 32
    • 0028910614 scopus 로고
    • Oxygen limitation can induce microbial secondary metabolite formation: Investigations with miniature electrodes in shaker and bioreactor culture
    • Clark, G. J.; Langley D.; Bushell, M. E. Oxygen limitation can induce microbial secondary metabolite formation: investigations with miniature electrodes in shaker and bioreactor culture. Microbiology 1995, 141, 663-669.
    • (1995) Microbiology , vol.141 , pp. 663-669
    • Clark, G.J.1    Langley, D.2    Bushell, M.E.3
  • 34
    • 0027455631 scopus 로고
    • Identification of a Saccharopolyspora erythraea gene required for the final hydroxylation step in erythromycin biosynthesis
    • Stassi, D.; Donadio, S.; Staver, M. J.; Katz, L. Identification of a Saccharopolyspora erythraea gene required for the final hydroxylation step in erythromycin biosynthesis. J. Bacteriol. 1993, 175, 182-189.
    • (1993) J. Bacteriol. , vol.175 , pp. 182-189
    • Stassi, D.1    Donadio, S.2    Staver, M.J.3    Katz, L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.