-
1
-
-
0031149766
-
Cognitive function in amyotrophic lateral sclerosis
-
Abe K., Fujimura H., Toyooka K., Sakoda S., Yorifuji S., Yanagihara T. Cognitive function in amyotrophic lateral sclerosis. J. Neurol. Sci. 1997, 148:95-100.
-
(1997)
J. Neurol. Sci.
, vol.148
, pp. 95-100
-
-
Abe, K.1
Fujimura, H.2
Toyooka, K.3
Sakoda, S.4
Yorifuji, S.5
Yanagihara, T.6
-
2
-
-
56249097900
-
Neuroscience: the plague plan
-
Abbott A. Neuroscience: the plague plan. Nature 2008, 456:161-164.
-
(2008)
Nature
, vol.456
, pp. 161-164
-
-
Abbott, A.1
-
3
-
-
33947415626
-
Hippocampal sclerosis dementia differs from hippocampal sclerosis in frontal lobe degeneration
-
Amador-Ortiz C., Ahmed Z., Zehr C., Dickson D.W. Hippocampal sclerosis dementia differs from hippocampal sclerosis in frontal lobe degeneration. Acta Neuropathol. 2007, 113:245-252.
-
(2007)
Acta Neuropathol.
, vol.113
, pp. 245-252
-
-
Amador-Ortiz, C.1
Ahmed, Z.2
Zehr, C.3
Dickson, D.W.4
-
4
-
-
34249949338
-
TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease
-
Amador-Ortiz C., Lin W.L., Ahmed Z., Personett D., Davies P., Duara R., Graff-Radford N.R., Hutton M.L., Dickson D.W. TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease. Ann. Neurol. 2007, 61:435-445.
-
(2007)
Ann. Neurol.
, vol.61
, pp. 435-445
-
-
Amador-Ortiz, C.1
Lin, W.L.2
Ahmed, Z.3
Personett, D.4
Davies, P.5
Duara, R.6
Graff-Radford, N.R.7
Hutton, M.L.8
Dickson, D.W.9
-
5
-
-
59249097160
-
Phosphorylated TDP-43 in Alzheimer's disease and dementia with Lewy bodies
-
Arai T., Mackenzie I.R., Hasegawa M., Nonoka T., Niizato K., Tsuchiya K., Iritani S., Onaya M., Akiyama H. Phosphorylated TDP-43 in Alzheimer's disease and dementia with Lewy bodies. Acta Neuropathol. 2009, 117:125-136.
-
(2009)
Acta Neuropathol.
, vol.117
, pp. 125-136
-
-
Arai, T.1
Mackenzie, I.R.2
Hasegawa, M.3
Nonoka, T.4
Niizato, K.5
Tsuchiya, K.6
Iritani, S.7
Onaya, M.8
Akiyama, H.9
-
6
-
-
0026740795
-
Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease
-
Arriagada P.V., Growdon J.H., Hedley-Whyte E.T., Hyman B.T. Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease. Neurology 1992, 42:631-639.
-
(1992)
Neurology
, vol.42
, pp. 631-639
-
-
Arriagada, P.V.1
Growdon, J.H.2
Hedley-Whyte, E.T.3
Hyman, B.T.4
-
7
-
-
0032787063
-
MRI volumes of amygdala and hippocampus in non-mentally retarded autistic adolescents and adults
-
Aylward E.H., Minshew N.J., Goldstein G., Honeycutt N.A., Augustine A.M., Yates K.O., Barta P.E., Pearlson G.D. MRI volumes of amygdala and hippocampus in non-mentally retarded autistic adolescents and adults. Neurology 1999, 53:2145-2150.
-
(1999)
Neurology
, vol.53
, pp. 2145-2150
-
-
Aylward, E.H.1
Minshew, N.J.2
Goldstein, G.3
Honeycutt, N.A.4
Augustine, A.M.5
Yates, K.O.6
Barta, P.E.7
Pearlson, G.D.8
-
8
-
-
34147125835
-
Accumulation of pathological tau species and memory loss in a conditional model of tauopathy
-
Berger Z., Roder H., Hanna A., Carlson A., Rangachari V., Yue M., Wszolek Z., Ashe K., Knight J., Dickson D., Andorfer C., Rosenberry T.L., Lewis J., Hutton M., Janus C. Accumulation of pathological tau species and memory loss in a conditional model of tauopathy. J. Neurosci. 2007, 27:3650-3662.
-
(2007)
J. Neurosci.
, vol.27
, pp. 3650-3662
-
-
Berger, Z.1
Roder, H.2
Hanna, A.3
Carlson, A.4
Rangachari, V.5
Yue, M.6
Wszolek, Z.7
Ashe, K.8
Knight, J.9
Dickson, D.10
Andorfer, C.11
Rosenberry, T.L.12
Lewis, J.13
Hutton, M.14
Janus, C.15
-
9
-
-
0028861585
-
Neocortical neurofibrillary tangles correlate with dementia severity in Alzheimer's disease
-
Bierer L.M., Hof P.R., Purohit D.P., Carlin L., Schmeidler J., Davis K.L., Perl D.P. Neocortical neurofibrillary tangles correlate with dementia severity in Alzheimer's disease. Arch. Neurol. 1995, 52:81-88.
-
(1995)
Arch. Neurol.
, vol.52
, pp. 81-88
-
-
Bierer, L.M.1
Hof, P.R.2
Purohit, D.P.3
Carlin, L.4
Schmeidler, J.5
Davis, K.L.6
Perl, D.P.7
-
10
-
-
0025863618
-
Neuropathological stageing of Alzheimer-related changes
-
Braak H., Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol. 1991, 82:239-259.
-
(1991)
Acta Neuropathol.
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
11
-
-
70349638299
-
Advances in tau-focused drug discovery for Alzheimer's disease and related tauopathies
-
Brunden K.R., Trojanowski J.Q., Lee V.M. Advances in tau-focused drug discovery for Alzheimer's disease and related tauopathies. Nat. Rev. Drug Discov. 2009, 9:749-751.
-
(2009)
Nat. Rev. Drug Discov.
, vol.9
, pp. 749-751
-
-
Brunden, K.R.1
Trojanowski, J.Q.2
Lee, V.M.3
-
13
-
-
0026342276
-
The N terminal region of human tau is present in Alzheimer's disease protein A68 and is incorporated into paired helical filaments
-
Crowe A., Ksiezak-Reding H., Liu W.K., Dickson D.W., Yen S.H. The N terminal region of human tau is present in Alzheimer's disease protein A68 and is incorporated into paired helical filaments. Am. J. Pathol. 1991, 139:1463-1470.
-
(1991)
Am. J. Pathol.
, vol.139
, pp. 1463-1470
-
-
Crowe, A.1
Ksiezak-Reding, H.2
Liu, W.K.3
Dickson, D.W.4
Yen, S.H.5
-
14
-
-
0345707547
-
The aging hippocampus: cognitive, biochemical and structural findings
-
Driscoll I., Hamilton D.A., Petropoulos H., Yeo R.A., Brooks W.M., Baumgartner R.N., Sutherland R.J. The aging hippocampus: cognitive, biochemical and structural findings. Cereb. Cortex 2003, 13:1344-1351.
-
(2003)
Cereb. Cortex
, vol.13
, pp. 1344-1351
-
-
Driscoll, I.1
Hamilton, D.A.2
Petropoulos, H.3
Yeo, R.A.4
Brooks, W.M.5
Baumgartner, R.N.6
Sutherland, R.J.7
-
15
-
-
84856539246
-
Alzheimer's failure raises questions about disease-modifying strategies
-
Extance A. Alzheimer's failure raises questions about disease-modifying strategies. Nat. Rev. Drug Discov. 2010, 8:783-793.
-
(2010)
Nat. Rev. Drug Discov.
, vol.8
, pp. 783-793
-
-
Extance, A.1
-
16
-
-
0032925257
-
Hippocampal and entorhinal cortex atrophy in frontotemporal dementia and Alzheimer's disease
-
Frisoni G.B., Laakso M.P., Beltramello A., Geroldi C., Bianchetti A., Soininen H., Trabucchi M. Hippocampal and entorhinal cortex atrophy in frontotemporal dementia and Alzheimer's disease. Neurology 1999, 52:91-100.
-
(1999)
Neurology
, vol.52
, pp. 91-100
-
-
Frisoni, G.B.1
Laakso, M.P.2
Beltramello, A.3
Geroldi, C.4
Bianchetti, A.5
Soininen, H.6
Trabucchi, M.7
-
17
-
-
0037015049
-
Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy
-
Gao G.P., Alvira M.R., Wang L., Calcedo R., Johnston J., Wilson J.M. Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy. Proc. Natl. Acad. Sci. U. S. A. 2002, 99:11854-11859.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 11854-11859
-
-
Gao, G.P.1
Alvira, M.R.2
Wang, L.3
Calcedo, R.4
Johnston, J.5
Wilson, J.M.6
-
18
-
-
2642512201
-
Clades of Adeno-associated viruses are widely disseminated in human tissues
-
Gao G., Vandenberghe L.H., Alvira M.R., Lu Y., Calcedo R., Zhou X., Wilson J.M. Clades of Adeno-associated viruses are widely disseminated in human tissues. J. Virol. 2004, 78:6381-6388.
-
(2004)
J. Virol.
, vol.78
, pp. 6381-6388
-
-
Gao, G.1
Vandenberghe, L.H.2
Alvira, M.R.3
Lu, Y.4
Calcedo, R.5
Zhou, X.6
Wilson, J.M.7
-
19
-
-
77949897022
-
Amyotrophic lateral sclerosis and frontotemporal lobar degeneration: a spectrum of TDP-43 proteinopathies
-
Geser F., Lee V.M., Trojanowski J.Q. Amyotrophic lateral sclerosis and frontotemporal lobar degeneration: a spectrum of TDP-43 proteinopathies. Neuropathology 2010, 30:103-112.
-
(2010)
Neuropathology
, vol.30
, pp. 103-112
-
-
Geser, F.1
Lee, V.M.2
Trojanowski, J.Q.3
-
20
-
-
0034123457
-
A qualitative and quantitative study of grumose degeneration in progressive supranuclear palsy
-
Ishizawa K., Lin W.L., Tiseo P., Honer W.G., Davies P., Dickson D.W. A qualitative and quantitative study of grumose degeneration in progressive supranuclear palsy. J. Neuropathol. Exp. Neurol. 2000, 59:513-524.
-
(2000)
J. Neuropathol. Exp. Neurol.
, vol.59
, pp. 513-524
-
-
Ishizawa, K.1
Lin, W.L.2
Tiseo, P.3
Honer, W.G.4
Davies, P.5
Dickson, D.W.6
-
21
-
-
77955322042
-
Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models
-
Ittner L.M., Ke Y.D., Delerue F., Bi M., Gladbach A., van Eersel J., Wölfing H., Chieng B.C., Christie M.J., Napier I.A., Eckert A., Staufenbiel M., Hardeman E., Götz J. Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models. Cell 2010, 42:387-397.
-
(2010)
Cell
, vol.42
, pp. 387-397
-
-
Ittner, L.M.1
Ke, Y.D.2
Delerue, F.3
Bi, M.4
Gladbach, A.5
van Eersel, J.6
Wölfing, H.7
Chieng, B.C.8
Christie, M.J.9
Napier, I.A.10
Eckert, A.11
Staufenbiel, M.12
Hardeman, E.13
Götz, J.14
-
22
-
-
0035986214
-
Use of excitotoxins to lesion the hippocampus: update
-
Jarrard L.E. Use of excitotoxins to lesion the hippocampus: update. Hippocampus 2002, 12:405-414.
-
(2002)
Hippocampus
, vol.12
, pp. 405-414
-
-
Jarrard, L.E.1
-
23
-
-
70349705552
-
AAV-tau mediates pyramidal neurodegeneration by cell-cycle re-entry without neurofibrillary tangle formation in wild-type mice
-
Jaworski T., Dewachter I., Lechat B., Croes S., Termont A., Demedts D., Borghgraef P., Devijver H., Filipkowski R.K., Kaczmarek L., Kügler S., Van Leuven F. AAV-tau mediates pyramidal neurodegeneration by cell-cycle re-entry without neurofibrillary tangle formation in wild-type mice. PLoS One 2009, 4:e7280.
-
(2009)
PLoS One
, vol.4
-
-
Jaworski, T.1
Dewachter, I.2
Lechat, B.3
Croes, S.4
Termont, A.5
Demedts, D.6
Borghgraef, P.7
Devijver, H.8
Filipkowski, R.K.9
Kaczmarek, L.10
Kügler, S.11
Van Leuven, F.12
-
24
-
-
0033198043
-
CAMP-dependent protein kinase phosphorylations on tau in Alzheimer's disease
-
Jicha G.A., Weaver C., Lane E., Vianna C., Kress Y., Rockwood J., Davies P. cAMP-dependent protein kinase phosphorylations on tau in Alzheimer's disease. J. Neurosci. 1999, 19:7486-7494.
-
(1999)
J. Neurosci.
, vol.19
, pp. 7486-7494
-
-
Jicha, G.A.1
Weaver, C.2
Lane, E.3
Vianna, C.4
Kress, Y.5
Rockwood, J.6
Davies, P.7
-
25
-
-
34548575051
-
Hippocampal sclerosis in tau-negative frontotemporal lobar degeneration
-
Josephs K.A., Dickson D.W. Hippocampal sclerosis in tau-negative frontotemporal lobar degeneration. Neurobiol. Aging 2007, 28:1718-1722.
-
(2007)
Neurobiol. Aging
, vol.28
, pp. 1718-1722
-
-
Josephs, K.A.1
Dickson, D.W.2
-
26
-
-
1542784350
-
Rapid neurofibrillary tangle formation after localized gene transfer of mutated tau
-
Klein R.L., Lin W.L., Dickson D.W., Lewis J., Hutton M., Duff K., Meyer E.M., King M.A. Rapid neurofibrillary tangle formation after localized gene transfer of mutated tau. Am. J. Pathol. 2004, 164:347-353.
-
(2004)
Am. J. Pathol.
, vol.164
, pp. 347-353
-
-
Klein, R.L.1
Lin, W.L.2
Dickson, D.W.3
Lewis, J.4
Hutton, M.5
Duff, K.6
Meyer, E.M.7
King, M.A.8
-
27
-
-
32944471565
-
Efficient neuronal gene transfer with AAV8 leads to neurotoxic levels of tau or green fluorescent proteins
-
Klein R.L., Dayton R.D., Leidenheimer N.J., Jansen K., Golde T.E., Zweig R.M. Efficient neuronal gene transfer with AAV8 leads to neurotoxic levels of tau or green fluorescent proteins. Mol. Ther. 2006, 13:517-527.
-
(2006)
Mol. Ther.
, vol.13
, pp. 517-527
-
-
Klein, R.L.1
Dayton, R.D.2
Leidenheimer, N.J.3
Jansen, K.4
Golde, T.E.5
Zweig, R.M.6
-
28
-
-
37549061385
-
AAV 8, 9, Rh10, Rh43 vector gene transfer in the rat brain: effects of serotype, promoter and purification method
-
Klein R.L., Dayton R.D., Tatom J.B., Henderson K.M., Henning P.P. AAV 8, 9, Rh10, Rh43 vector gene transfer in the rat brain: effects of serotype, promoter and purification method. Mol. Ther. 2008, 16:89-96.
-
(2008)
Mol. Ther.
, vol.16
, pp. 89-96
-
-
Klein, R.L.1
Dayton, R.D.2
Tatom, J.B.3
Henderson, K.M.4
Henning, P.P.5
-
29
-
-
78650177451
-
Pronounced microgliosis and neurodegeneration in aged rats after tau gene transfer
-
Klein R.L., Dayton R.D., Diaczynsky C.G., Wang D.B. Pronounced microgliosis and neurodegeneration in aged rats after tau gene transfer. Neurobiol. Aging 2010, 31:2091-2102.
-
(2010)
Neurobiol. Aging
, vol.31
, pp. 2091-2102
-
-
Klein, R.L.1
Dayton, R.D.2
Diaczynsky, C.G.3
Wang, D.B.4
-
30
-
-
0030222037
-
Microglia: a sensor for pathological events in the CNS
-
Kreutzberg G.W. Microglia: a sensor for pathological events in the CNS. Trends Neurosci. 1996, 19:312-318.
-
(1996)
Trends Neurosci.
, vol.19
, pp. 312-318
-
-
Kreutzberg, G.W.1
-
31
-
-
0034091250
-
Hippocampus and entorhinal cortex in frontotemporal dementia and Alzheimer's disease: a morphometric MRI study
-
Laakso M.P., Frisoni G.B., Könönen M., Mikkonen M., Beltramello A., Geroldi C., Bianchetti A., Trabucchi M., Soininen H., Aronen H.J. Hippocampus and entorhinal cortex in frontotemporal dementia and Alzheimer's disease: a morphometric MRI study. Biol. Psychiatry 2000, 47:1056-1063.
-
(2000)
Biol. Psychiatry
, vol.47
, pp. 1056-1063
-
-
Laakso, M.P.1
Frisoni, G.B.2
Könönen, M.3
Mikkonen, M.4
Beltramello, A.5
Geroldi, C.6
Bianchetti, A.7
Trabucchi, M.8
Soininen, H.9
Aronen, H.J.10
-
32
-
-
0033588890
-
Enhanced expression of transgenes from adeno-associated virus vectors with the woodchuck hepatitis virus posttranscriptional regulatory element: implications for gene therapy
-
Loeb J.E., Cordier W.S., Harris M.E., Weitzman M.D., Hope T.J. Enhanced expression of transgenes from adeno-associated virus vectors with the woodchuck hepatitis virus posttranscriptional regulatory element: implications for gene therapy. Hum. Gene Ther. 1999, 10:2295-2305.
-
(1999)
Hum. Gene Ther.
, vol.10
, pp. 2295-2305
-
-
Loeb, J.E.1
Cordier, W.S.2
Harris, M.E.3
Weitzman, M.D.4
Hope, T.J.5
-
33
-
-
84856525244
-
The ventral hippocampus is necessary for expressing a spatial memory
-
(Epub Jun 12)
-
Loureiro M., Lecourtier L., Engeln M., Lopez J., Cosquer B., Geiger K., Kelche C., Cassel J.C., Pereira de Vasconcelos A. The ventral hippocampus is necessary for expressing a spatial memory. Brain Struct. Funct. 2011, (Epub Jun 12).
-
(2011)
Brain Struct. Funct.
-
-
Loureiro, M.1
Lecourtier, L.2
Engeln, M.3
Lopez, J.4
Cosquer, B.5
Geiger, K.6
Kelche, C.7
Cassel, J.C.8
Pereira de Vasconcelos, A.9
-
34
-
-
77955662948
-
Expression of a conditioned place preference or spatial navigation task following muscimol-induced inactivations of the amygdala or dorsal hippocampus: a double dissociation in the retrograde direction
-
McDonald R.J., Yim T.T., Lehmann H., Sparks F.T., Zelinski E.L., Sutherland R.J., Hong N.S. Expression of a conditioned place preference or spatial navigation task following muscimol-induced inactivations of the amygdala or dorsal hippocampus: a double dissociation in the retrograde direction. Brain Res. Bull. 2010, 83:29-37.
-
(2010)
Brain Res. Bull.
, vol.83
, pp. 29-37
-
-
McDonald, R.J.1
Yim, T.T.2
Lehmann, H.3
Sparks, F.T.4
Zelinski, E.L.5
Sutherland, R.J.6
Hong, N.S.7
-
35
-
-
68449096263
-
Neuropathology. A late hit for pro football players
-
Miller G. Neuropathology. A late hit for pro football players. Science 2009, 325:670-672.
-
(2009)
Science
, vol.325
, pp. 670-672
-
-
Miller, G.1
-
36
-
-
0021173996
-
Developments of a water-maze procedure for studying spatial learning in the rat
-
Morris R. Developments of a water-maze procedure for studying spatial learning in the rat. J. Neurosci. Methods 1984, 11:47-60.
-
(1984)
J. Neurosci. Methods
, vol.11
, pp. 47-60
-
-
Morris, R.1
-
37
-
-
34447323183
-
Cortical neuronal and glial pathology in TgTauP301L transgenic mice: neuronal degeneration, memory disturbance, and phenotypic variation
-
Murakami T., Paitel E., Kawarabayashi T., Ikeda M., Chishti M.A., Janus C., Matsubara E., Sasaki A., Kawarai T., Phinney A.L., Harigaya Y., Horne P., Egashira N., Mishima K., Hanna A., Yang J., Iwasaki K., Takahashi M., Fujiwara M., Ishiguro K., Bergeron C., Carlson G.A., Abe K., Westaway D., St George-Hyslop P., Shoji M. Cortical neuronal and glial pathology in TgTauP301L transgenic mice: neuronal degeneration, memory disturbance, and phenotypic variation. Am. J. Pathol. 2006, 169:1365-1375.
-
(2006)
Am. J. Pathol.
, vol.169
, pp. 1365-1375
-
-
Murakami, T.1
Paitel, E.2
Kawarabayashi, T.3
Ikeda, M.4
Chishti, M.A.5
Janus, C.6
Matsubara, E.7
Sasaki, A.8
Kawarai, T.9
Phinney, A.L.10
Harigaya, Y.11
Horne, P.12
Egashira, N.13
Mishima, K.14
Hanna, A.15
Yang, J.16
Iwasaki, K.17
Takahashi, M.18
Fujiwara, M.19
Ishiguro, K.20
Bergeron, C.21
Carlson, G.A.22
Abe, K.23
Westaway, D.24
St George-Hyslop, P.25
Shoji, M.26
more..
-
38
-
-
33749632259
-
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Neumann M., Sampathu D.M., Kwong L.K., Truax A.C., Micsenyi M.C., Chou T.T., Bruce J., Schuck T., Grossman M., Clark C.M., McCluskey L.F., Miller B.L., Masliah E., Mackenzie I.R., Feldman H., Feiden W., Kretzschmar H.A., Trojanowski J.Q., Lee V.M. Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 2006, 314:130-133.
-
(2006)
Science
, vol.314
, pp. 130-133
-
-
Neumann, M.1
Sampathu, D.M.2
Kwong, L.K.3
Truax, A.C.4
Micsenyi, M.C.5
Chou, T.T.6
Bruce, J.7
Schuck, T.8
Grossman, M.9
Clark, C.M.10
McCluskey, L.F.11
Miller, B.L.12
Masliah, E.13
Mackenzie, I.R.14
Feldman, H.15
Feiden, W.16
Kretzschmar, H.A.17
Trojanowski, J.Q.18
Lee, V.M.19
-
39
-
-
0033870226
-
Influence of promoter and WHV post-transcriptional regulatory element on AAV-mediated transgene expression in the rat brain
-
Paterna J.C., Moccetti T., Mura A., Feldon J., Büeler H. Influence of promoter and WHV post-transcriptional regulatory element on AAV-mediated transgene expression in the rat brain. Gene Ther. 2000, 7:1304-1311.
-
(2000)
Gene Ther.
, vol.7
, pp. 1304-1311
-
-
Paterna, J.C.1
Moccetti, T.2
Mura, A.3
Feldon, J.4
Büeler, H.5
-
40
-
-
2942689239
-
Transduction profiles of recombinant adeno-associated virus vectors derived from serotypes 2 and 5 in the nigrostriatal system of rats
-
Paterna J.C., Feldon J., Büeler H. Transduction profiles of recombinant adeno-associated virus vectors derived from serotypes 2 and 5 in the nigrostriatal system of rats. J. Virol. 2004, 78:6808-6817.
-
(2004)
J. Virol.
, vol.78
, pp. 6808-6817
-
-
Paterna, J.C.1
Feldon, J.2
Büeler, H.3
-
42
-
-
0034212887
-
Adeno-associated virus vectors: activity and applications in the CNS
-
Peel A.L., Klein R.L. Adeno-associated virus vectors: activity and applications in the CNS. J. Neurosci. Methods 2000, 98:95-104.
-
(2000)
J. Neurosci. Methods
, vol.98
, pp. 95-104
-
-
Peel, A.L.1
Klein, R.L.2
-
43
-
-
35248823549
-
Cognitive impairment in amyotrophic lateral sclerosis
-
Phukan J., Pender N.P., Hardiman O. Cognitive impairment in amyotrophic lateral sclerosis. Lancet Neurol. 2007, 6:994-1003.
-
(2007)
Lancet Neurol.
, vol.6
, pp. 994-1003
-
-
Phukan, J.1
Pender, N.P.2
Hardiman, O.3
-
44
-
-
78149410465
-
Focal expression of mutated tau in entorhinal cortex neurons of rats impairs spatial working memory
-
Ramirez J.J., Poulton W.E., Knelson E., Barton C., King M.A., Klein R.L. Focal expression of mutated tau in entorhinal cortex neurons of rats impairs spatial working memory. Behav. Brain Res. 2011, 216:332-340.
-
(2011)
Behav. Brain Res.
, vol.216
, pp. 332-340
-
-
Ramirez, J.J.1
Poulton, W.E.2
Knelson, E.3
Barton, C.4
King, M.A.5
Klein, R.L.6
-
45
-
-
27944491109
-
Age-dependent neurofibrillary tangle formation, neuron loss, and memory impairment in a mouse model of human tauopathy (P301L)
-
Ramsden M., Kotilinek L., Forster C., Paulson J., McGowan E., SantaCruz K., Guimaraes A., Yue M., Lewis J., Carlson G., Hutton M., Ashe K.H. Age-dependent neurofibrillary tangle formation, neuron loss, and memory impairment in a mouse model of human tauopathy (P301L). J. Neurosci. 2005, 25:10637-10647.
-
(2005)
J. Neurosci.
, vol.25
, pp. 10637-10647
-
-
Ramsden, M.1
Kotilinek, L.2
Forster, C.3
Paulson, J.4
McGowan, E.5
SantaCruz, K.6
Guimaraes, A.7
Yue, M.8
Lewis, J.9
Carlson, G.10
Hutton, M.11
Ashe, K.H.12
-
46
-
-
34248181511
-
Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model
-
Roberson E.D., Scearce-Levie K., Palop J.J., Yan F., Cheng I.H., Wu T., Gerstein H., Yu G.Q., Mucke L. Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model. Science 2007, 316:750-754.
-
(2007)
Science
, vol.316
, pp. 750-754
-
-
Roberson, E.D.1
Scearce-Levie, K.2
Palop, J.J.3
Yan, F.4
Cheng, I.H.5
Wu, T.6
Gerstein, H.7
Yu, G.Q.8
Mucke, L.9
-
47
-
-
22344438508
-
Tau suppression in a neurodegenerative mouse model improves memory function
-
Santacruz K., Lewis J., Spires T., Paulson J., Kotilinek L., Ingelsson M., Guimaraes A., DeTure M., Ramsden M., McGowan E., Forster C., Yue M., Orne J., Janus C., Mariash A., Kuskowski M., Hyman B., Hutton M., Ashe K.H. Tau suppression in a neurodegenerative mouse model improves memory function. Science 2005, 309:476-481.
-
(2005)
Science
, vol.309
, pp. 476-481
-
-
Santacruz, K.1
Lewis, J.2
Spires, T.3
Paulson, J.4
Kotilinek, L.5
Ingelsson, M.6
Guimaraes, A.7
DeTure, M.8
Ramsden, M.9
McGowan, E.10
Forster, C.11
Yue, M.12
Orne, J.13
Janus, C.14
Mariash, A.15
Kuskowski, M.16
Hyman, B.17
Hutton, M.18
Ashe, K.H.19
-
48
-
-
41849099215
-
Regional hippocampal atrophy in multiple sclerosis
-
Sicotte N.L., Kern K.C., Giesser B.S., Arshanapalli A., Schultz A., Montag M., Wang H., Bookheimer S.Y. Regional hippocampal atrophy in multiple sclerosis. Brain 2008, 131:1134-1141.
-
(2008)
Brain
, vol.131
, pp. 1134-1141
-
-
Sicotte, N.L.1
Kern, K.C.2
Giesser, B.S.3
Arshanapalli, A.4
Schultz, A.5
Montag, M.6
Wang, H.7
Bookheimer, S.Y.8
-
49
-
-
57049182428
-
Progression of hippocampal degeneration in amyotrophic lateral sclerosis with or without memory impairment: distinction from Alzheimer disease
-
Takeda T., Uchihara T., Arai N., Mizutani T., Iwata M. Progression of hippocampal degeneration in amyotrophic lateral sclerosis with or without memory impairment: distinction from Alzheimer disease. Acta Neuropathol. 2009, 117:35-44.
-
(2009)
Acta Neuropathol.
, vol.117
, pp. 35-44
-
-
Takeda, T.1
Uchihara, T.2
Arai, N.3
Mizutani, T.4
Iwata, M.5
-
50
-
-
63949083624
-
Mimicking aspects of frontotemporal lobar degeneration and Lou Gehrig's disease in rats via TDP-43 overexpression
-
Tatom J.B., Wang D.B., Dayton R.D., Skalli O., Hutton M.L., Dickson D.W., Klein R.L. Mimicking aspects of frontotemporal lobar degeneration and Lou Gehrig's disease in rats via TDP-43 overexpression. Mol. Ther. 2009, 17:607-613.
-
(2009)
Mol. Ther.
, vol.17
, pp. 607-613
-
-
Tatom, J.B.1
Wang, D.B.2
Dayton, R.D.3
Skalli, O.4
Hutton, M.L.5
Dickson, D.W.6
Klein, R.L.7
-
51
-
-
33745612973
-
Comprehensive dissection of the medial temporal lobe in AD: measurement of hippocampus, amygdala, entorhinal, perirhinal and parahippocampal cortices using MRI
-
Teipel S.J., Pruessner J.C., Faltraco F., Born C., Rocha-Unold M., Evans A., Möller H.J., Hampel H. Comprehensive dissection of the medial temporal lobe in AD: measurement of hippocampus, amygdala, entorhinal, perirhinal and parahippocampal cortices using MRI. J. Neurol. 2006, 253:794-800.
-
(2006)
J. Neurol.
, vol.253
, pp. 794-800
-
-
Teipel, S.J.1
Pruessner, J.C.2
Faltraco, F.3
Born, C.4
Rocha-Unold, M.5
Evans, A.6
Möller, H.J.7
Hampel, H.8
-
52
-
-
77955395385
-
Elevated expression of TDP-43 in the forebrain of mice is sufficient to cause neurological and pathological phenotypes mimicking FTLD-U
-
Tsai K.J., Yang C.H., Fang Y.H., Cho K.H., Chien W.L., Wang W.T., Wu T.W., Lin C.P., Fu W.M., Shen C.K. Elevated expression of TDP-43 in the forebrain of mice is sufficient to cause neurological and pathological phenotypes mimicking FTLD-U. J. Exp. Med. 2010, 207:1661-1673.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 1661-1673
-
-
Tsai, K.J.1
Yang, C.H.2
Fang, Y.H.3
Cho, K.H.4
Chien, W.L.5
Wang, W.T.6
Wu, T.W.7
Lin, C.P.8
Fu, W.M.9
Shen, C.K.10
-
53
-
-
69249237024
-
The neonatal ventral hippocampal lesion as a heuristic neurodevelopmental model of schizophrenia
-
Tseng K.Y., Chambers R.A., Lipska B.K. The neonatal ventral hippocampal lesion as a heuristic neurodevelopmental model of schizophrenia. Behav. Brain Res. 2009, 204:295-305.
-
(2009)
Behav. Brain Res.
, vol.204
, pp. 295-305
-
-
Tseng, K.Y.1
Chambers, R.A.2
Lipska, B.K.3
-
54
-
-
44649137415
-
Concomitant TAR-DNA-binding protein 43 pathology is present in Alzheimer disease and corticobasal degeneration but not in other tauopathies
-
Uryu K., Nakashima-Yasuda H., Forman M.S., Kwong L.K., Clark C.M., Grossman M., Miller B.L., Kretzschmar H.A., Lee V.M., Trojanowski J.Q., Neumann M. Concomitant TAR-DNA-binding protein 43 pathology is present in Alzheimer disease and corticobasal degeneration but not in other tauopathies. J. Neuropathol. Exp. Neurol. 2008, 67:555-564.
-
(2008)
J. Neuropathol. Exp. Neurol.
, vol.67
, pp. 555-564
-
-
Uryu, K.1
Nakashima-Yasuda, H.2
Forman, M.S.3
Kwong, L.K.4
Clark, C.M.5
Grossman, M.6
Miller, B.L.7
Kretzschmar, H.A.8
Lee, V.M.9
Trojanowski, J.Q.10
Neumann, M.11
-
55
-
-
78650903887
-
Expansive gene transfer to the rat CNS and amyotrophic lateral sclerosis relevant sequelae when TDP-43 is overexpressed
-
Wang D.B., Dayton R.D., Henning P.P., Cain C.D., Zhao L.R., Schrott L.M., Orchard E.A., Knight D.S., Klein R.L. Expansive gene transfer to the rat CNS and amyotrophic lateral sclerosis relevant sequelae when TDP-43 is overexpressed. Mol. Ther. 2010, 18:2064-2074.
-
(2010)
Mol. Ther.
, vol.18
, pp. 2064-2074
-
-
Wang, D.B.1
Dayton, R.D.2
Henning, P.P.3
Cain, C.D.4
Zhao, L.R.5
Schrott, L.M.6
Orchard, E.A.7
Knight, D.S.8
Klein, R.L.9
-
56
-
-
80054707323
-
Genetic strategies to study TDP-43 in rodents and to develop preclinical therapeutics for amyotrophic lateral sclerosis
-
Wang D.B., Gitcho M.A., Kraemer B.C., Klein R.L. Genetic strategies to study TDP-43 in rodents and to develop preclinical therapeutics for amyotrophic lateral sclerosis. Eur. J. Neurosci. 2011, 34:1179-1188.
-
(2011)
Eur. J. Neurosci.
, vol.34
, pp. 1179-1188
-
-
Wang, D.B.1
Gitcho, M.A.2
Kraemer, B.C.3
Klein, R.L.4
-
57
-
-
0019935804
-
Plaques, tangles and dementia. A quantitative study
-
Wilcock G.K., Esiri M.M. Plaques, tangles and dementia. A quantitative study. J. Neurol. Sci. 1982, 56:343-356.
-
(1982)
J. Neurol. Sci.
, vol.56
, pp. 343-356
-
-
Wilcock, G.K.1
Esiri, M.M.2
-
58
-
-
0022200969
-
Monoclonal antibodies to Alzheimer neurofibrillary tangles. 1. Identification of polypeptides
-
Yen S.H., Crowe A., Dickson D.W. Monoclonal antibodies to Alzheimer neurofibrillary tangles. 1. Identification of polypeptides. Am. J. Pathol. 1985, 120:282-291.
-
(1985)
Am. J. Pathol.
, vol.120
, pp. 282-291
-
-
Yen, S.H.1
Crowe, A.2
Dickson, D.W.3
-
59
-
-
33846538660
-
Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model
-
Yoshiyama Y., Higuchi M., Zhang B., Huang S.M., Iwata N., Saido T.C., Maeda J., Suhara T., Trojanowski J.Q., Lee V.M. Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model. Neuron 2007, 53:337-351.
-
(2007)
Neuron
, vol.53
, pp. 337-351
-
-
Yoshiyama, Y.1
Higuchi, M.2
Zhang, B.3
Huang, S.M.4
Iwata, N.5
Saido, T.C.6
Maeda, J.7
Suhara, T.8
Trojanowski, J.Q.9
Lee, V.M.10
-
60
-
-
0036428801
-
Production and purification of serotype 1, 2, and 5 recombinant adeno-associated viral vectors
-
Zolotukhin S., Potter M., Zolotukhin I., Sakai Y., Loiler S., Fraites T.J., Chiodo V.A., Phillipsberg T., Muzyczka N., Hauswirth W.W., Flotte T.R., Byrne B.J., Snyder R.O. Production and purification of serotype 1, 2, and 5 recombinant adeno-associated viral vectors. Methods 2002, 28:158-167.
-
(2002)
Methods
, vol.28
, pp. 158-167
-
-
Zolotukhin, S.1
Potter, M.2
Zolotukhin, I.3
Sakai, Y.4
Loiler, S.5
Fraites, T.J.6
Chiodo, V.A.7
Phillipsberg, T.8
Muzyczka, N.9
Hauswirth, W.W.10
Flotte, T.R.11
Byrne, B.J.12
Snyder, R.O.13
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