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Volumn 17, Issue 3, 2012, Pages 179-188

Reduction of tinnitus severity by the centrally acting muscle relaxant cyclobenzaprine: An open-label pilot study

Author keywords

Muscle relaxants; Phantom perception; Somatosensory system; Tinnitus

Indexed keywords

AMITRIPTYLINE; CENTRAL MUSCLE RELAXANT; CLONIDINE; CYCLOBENZAPRINE; DRUG DERIVATIVE; EPERISONE; ORPHENADRINE; PROPIOPHENONE DERIVATIVE; TIZANIDINE;

EID: 84856432171     PISSN: 14203030     EISSN: 14219700     Source Type: Journal    
DOI: 10.1159/000335657     Document Type: Article
Times cited : (21)

References (89)
  • 1
    • 1842454321 scopus 로고    scopus 로고
    • Objective high-frequency tinnitus of middle-ear myoclonus
    • DOI 10.1258/002221504322928044
    • Abdul-Baqi KJ: Objective high-frequency tinnitus of middle-ear myoclonus. J Laryngol Otol 2004; 118: 231-233. (Pubitemid 38446284)
    • (2004) Journal of Laryngology and Otology , vol.118 , Issue.3 , pp. 231-233
    • Abdul-Baqi, K.J.1
  • 2
    • 0019732445 scopus 로고
    • Norepinephrine-containing locus coeruleus neurons in behaving rats exhibit pronounced responses to non-noxious environmental stimuli
    • Aston-Jones G, Bloom FE: Norepinephrine-containing locus coeruleus neurons in behaving rats exhibit pronounced responses to nonnoxious environmental stimuli. J Neurosci 1981; 1: 887-900. (Pubitemid 11025877)
    • (1981) Journal of Neuroscience , vol.1 , Issue.8 , pp. 887-900
    • Aston-Jones, G.1    Bloom, F.E.2
  • 3
    • 0018819320 scopus 로고
    • Brainstem noradrenergic system depression by cyclobenzaprine
    • DOI 10.1016/0028-3908(80)90142-2
    • Barnes CD, Fung SJ, Gintautas J: Brainstem noradrenergic system depression by cyclobenzaprine. Neuropharmacology 1980; 19: 221-224. (Pubitemid 10119726)
    • (1980) Neuropharmacology , vol.19 , Issue.2 , pp. 221-224
    • Barnes, C.D.1    Fung, S.J.2    Gintautas, J.3
  • 4
    • 49349115135 scopus 로고    scopus 로고
    • Tinnitus and inferior colliculus activity in chinchillas related to three distinct patterns of cochlear trauma
    • Bauer CA, Turner JG, Caspary DM, Myers KS, Brozoski TJ: Tinnitus and inferior colliculus activity in chinchillas related to three distinct patterns of cochlear trauma. J Neurosci Res 2008; 86: 2564-2578.
    • (2008) J Neurosci Res , vol.86 , pp. 2564-2578
    • Bauer, C.A.1    Turner, J.G.2    Caspary, D.M.3    Myers, K.S.4    Brozoski, T.J.5
  • 5
    • 0035727530 scopus 로고    scopus 로고
    • Efficacy of amitriptyline in the treatment of subjective tinnitus
    • Bayar N, Boke B, Turan E, Belgin E: Efficacy of amitriptyline in the treatment of subjective tinnitus. J Otolaryngol 2001; 30: 300-303. (Pubitemid 34269923)
    • (2001) Journal of Otolaryngology , vol.30 , Issue.5 , pp. 300-303
    • Bayar, N.1    Boke, B.2    Turan, E.3    Belgin, E.4
  • 7
    • 0027372399 scopus 로고
    • Tinnitus aereum as an effect of increased tension in the lateral pterygoid muscle [5]
    • Bjorne A: Tinnitus aereum as an effect of increased tension in the lateral pterygoid muscle. Otolaryngol Head Neck Surg 1993; 109: 969. (Pubitemid 23360864)
    • (1993) Otolaryngology - Head and Neck Surgery , vol.109 , Issue.5 , pp. 969
    • Bjorne, A.1
  • 10
    • 49549091165 scopus 로고    scopus 로고
    • Efficacy and safety of eperisone in patients with low back pain: A double blind randomized study
    • Cabitza P, Randelli P: Efficacy and safety of eperisone in patients with low back pain: a double blind randomized study. Eur Rev Med Pharmacol Sci 2008; 12: 229-235.
    • (2008) Eur Rev Med Pharmacol Sci , vol.12 , pp. 229-235
    • Cabitza, P.1    Randelli, P.2
  • 11
    • 39049176103 scopus 로고    scopus 로고
    • Hearing loss and tinnitus prevention initiatives: Partnerships for success
    • Cacace AT: Hearing loss and tinnitus prevention initiatives: partnerships for success. Am J Audiol 2006; 15: 99-100.
    • (2006) Am J Audiol , vol.15 , pp. 99-100
    • Cacace, A.T.1
  • 13
    • 0031595435 scopus 로고    scopus 로고
    • 2- noradrenergic agonists and norepinephrine on locomotion in chronic spinal cats
    • Chau C, Barbeau H, Rossignol S: Effects of intrathecal alpha1-and alpha2-noradrenergic agonists and norepinephrine on locomotion in chronic spinal cats. J Neurophysiol 1998; 79: 2941-2963. (Pubitemid 28317025)
    • (1998) Journal of Neurophysiology , vol.79 , Issue.6 , pp. 2941-2963
    • Chau, C.1    Barbeau, H.2    Rossignol, S.3
  • 14
    • 0018817656 scopus 로고
    • Locus coeruleus-induced inhibition of dorsal cochlear nucleus neurons in comparison with lateral vestibular nucleus neurons
    • DOI 10.1016/0006-8993(80)91318-9
    • Chikamori Y, Sasa M, Fujimoto S, Takaori S, Matsuoka I: Locus coeruleus-induced inhibition of dorsal cochlear nucleus neurons in comparison with lateral vestibular nucleus neurons. Brain Res 1980; 194: 53-63. (Pubitemid 10069486)
    • (1980) Brain Research , vol.194 , Issue.1 , pp. 53-63
    • Chikamori, Y.1    Sasa, M.2    Fujimoto, S.3
  • 17
    • 0035836768 scopus 로고    scopus 로고
    • Tinnitus evoked by finger movement: Brain plasticity after peripheral deafferentation
    • Cullington H: Tinnitus evoked by finger movement: brain plasticity after peripheral deafferentation. Neurology 2001; 56: 978. (Pubitemid 32290822)
    • (2001) Neurology , vol.56 , Issue.7 , pp. 978
    • Cullington, H.1
  • 18
    • 35348918314 scopus 로고    scopus 로고
    • Drug treatments for tinnitus
    • DOI 10.1016/S0079-6123(07)66023-3, PII S0079612307660233, Tinnitus: Pathophysiology and Treatment
    • Darlington CL, Smith PF: Drug treatments for tinnitus. Prog Brain Res 2007; 166: 249-262. (Pubitemid 47588073)
    • (2007) Progress in Brain Research , vol.166 , pp. 249-262
    • Darlington, C.L.1    Smith, P.F.2
  • 19
    • 58749111653 scopus 로고    scopus 로고
    • Cross-modal interactions of auditory and somatic inputs in the brainstem and midbrain and their imbalance in tinnitus and deafness
    • Dehmel S, Cui YL, Shore SE: Cross-modal interactions of auditory and somatic inputs in the brainstem and midbrain and their imbalance in tinnitus and deafness. Am J Audiol 2008; 17:S193-S209.
    • (2008) Am J Audiol , vol.17
    • Dehmel, S.1    Cui, Y.L.2    Shore, S.E.3
  • 20
    • 79957689803 scopus 로고    scopus 로고
    • Phantom percepts: Tinnitus and pain as persisting aversive memory networks
    • De Ridder D, Elgoyhen AB, Romo R, Langguth B: Phantom percepts: tinnitus and pain as persisting aversive memory networks. Proc Natl Acad Sci USA 2011; 108: 8075-8080.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 8075-8080
    • De Ridder, D.1    Elgoyhen, A.B.2    Romo, R.3    Langguth, B.4
  • 21
    • 35348928205 scopus 로고    scopus 로고
    • Tinnitus in vascular conflict of the eighth cranial nerve: A surgical pathophysiological approach to ABR changes
    • DOI 10.1016/S0079-6123(07)66039-7, PII S0079612307660397, Tinnitus: Pathophysiology and Treatment
    • De Ridder D, Heijneman K, Haarman B, van der Loo E: Tinnitus in vascular conflict of the eighth cranial nerve: a surgical pathophysiological approach to ABR changes. Prog Brain Res 2007; 166: 401-411. (Pubitemid 47588086)
    • (2007) Progress in Brain Research , vol.166 , pp. 401-411
    • De Ridder, D.1    Heijneman, K.2    Haarman, B.3    Van Der Loo, E.4
  • 22
    • 10744224752 scopus 로고    scopus 로고
    • Functional anatomy of the human cochlear nerve and its role in microvascular decompressions for tinnitus
    • discussion 388-390
    • De Ridder D, Ryu H, Moller AR, Nowe V, Van de Heyning P, Verlooy J: Functional anatomy of the human cochlear nerve and its role in microvascular decompressions for tinnitus. Neurosurgery 2004; 54: 381-388, discussion 388-390.
    • (2004) Neurosurgery , vol.54 , pp. 381-388
    • De Ridder, D.1    Ryu, H.2    Moller, A.R.3    Nowe, V.4    Van De Heyning, P.5    Verlooy, J.6
  • 23
    • 22644442584 scopus 로고    scopus 로고
    • Transcranial magnetic stimulation for tinnitus: Influence of tinnitus duration on stimulation parameter choice and maximal tinnitus suppression
    • DOI 10.1097/01.mao.0000178146.91139.3c
    • De Ridder D, Verstraeten E, Van der Kelen K, De Mulder G, Sunaert S, Verlooy J, Van de Heyning P, Moller A: Transcranial magnetic stimulation for tinnitus: influence of tinnitus duration on stimulation parameter choice and maximal tinnitus suppression. Otol Neurotol 2005; 26: 616-619. (Pubitemid 41026084)
    • (2005) Otology and Neurotology , vol.26 , Issue.4 , pp. 616-619
    • De Ridder, D.1    Verstraeten, E.2    Van Der Kelen, K.3    De Mulder, G.4    Sunaert, S.5    Verlooy, J.6    Van De Heyning, P.7    Moller, A.8
  • 25
    • 0032770251 scopus 로고    scopus 로고
    • A review of randomized clinical trials in tinnitus
    • DOI 10.1097/00005537-199908000-00004
    • Dobie RA: A review of randomized clinical trials in tinnitus. Laryngoscope 1999; 109: 1202-1211. (Pubitemid 29379426)
    • (1999) Laryngoscope , vol.109 , Issue.8 , pp. 1202-1211
    • Dobie, R.A.1
  • 27
    • 35348889075 scopus 로고    scopus 로고
    • Pathophysiology of tinnitus
    • Eggermont JJ: Pathophysiology of tinnitus. Prog Brain Res 2007; 166: 19-35.
    • (2007) Prog Brain Res , vol.166 , pp. 19-35
    • Eggermont, J.J.1
  • 28
    • 5044234454 scopus 로고    scopus 로고
    • The neuroscience of tinnitus
    • DOI 10.1016/j.tins.2004.08.010, PII S0166223604002760
    • Eggermont JJ, Roberts LE: The neuroscience of tinnitus. Trends Neurosci 2004; 27: 676-682. (Pubitemid 39335838)
    • (2004) Trends in Neurosciences , vol.27 , Issue.11 , pp. 676-682
    • Eggermont, J.J.1    Roberts, L.E.2
  • 29
    • 77951024683 scopus 로고    scopus 로고
    • Pharmacological approaches to the treatment of tinnitus
    • Elgoyhen AB, Langguth B: Pharmacological approaches to the treatment of tinnitus. Drug Discov Today 2010; 15: 300-305.
    • (2010) Drug Discov Today , vol.15 , pp. 300-305
    • Elgoyhen, A.B.1    Langguth, B.2
  • 31
    • 35348906835 scopus 로고    scopus 로고
    • Tinnitus treatment: State of the art
    • Goodey R: Tinnitus treatment: state of the art. Prog Brain Res 2007; 166: 237-246.
    • (2007) Prog Brain Res , vol.166 , pp. 237-246
    • Goodey, R.1
  • 32
    • 79958726836 scopus 로고    scopus 로고
    • Noise-induced hearing injury and comorbidities among postdeployment US army soldiers: April 2003 through June 2009
    • Helfer TM, Jordan NN, Lee RB, Pietrusiak P, Cave K, Schairer K: Noise-induced hearing injury and comorbidities among postdeployment US army soldiers: April 2003 through June 2009. Am J Audiol 2011; 20: 33-41.
    • (2011) Am J Audiol , vol.20 , pp. 33-41
    • Helfer, T.M.1    Jordan, N.N.2    Lee, R.B.3    Pietrusiak, P.4    Cave, K.5    Schairer, K.6
  • 33
    • 12244271049 scopus 로고    scopus 로고
    • 2 receptors
    • DOI 10.1016/S0014-2999(02)02735-8, PII S0014299902027358
    • Honda M, Nishida T, Ono H: Tricyclic analogs cyclobenzaprine, amitriptyline and cyproheptadine inhibit the spinal reflex transmission through 5-HT 2 receptors. Eur J Pharmacol 2003; 458: 91-99. (Pubitemid 36050705)
    • (2003) European Journal of Pharmacology , vol.458 , Issue.1-2 , pp. 91-99
    • Honda, M.1    Nishida, T.2    Ono, H.3
  • 34
    • 0025806856 scopus 로고
    • Clinical and pharmacological review of the efficacy of orphenadrine and its combination with paracetamol in painful conditions
    • Hunskaar S, Donnell D: Clinical and pharmacological review of the efficacy of orphenadrine and its combination with paracetamol in painful conditions. J Int Med Res 1991; 19: 71-87.
    • (1991) J Int Med Res , vol.19 , pp. 71-87
    • Hunskaar, S.1    Donnell, D.2
  • 35
    • 0026530941 scopus 로고
    • Antinociceptive effects of tizanidine, diazepam and eperisone in isolated spinal cord-tail preparations of newborn rat
    • Ishizuki M, Yanagisawa M: Antinociceptive effects of tizanidine, diazepam and eperisone in isolated spinal cord-tail preparations of newborn rat. Pain 1992; 48: 101-106.
    • (1992) Pain , vol.48 , pp. 101-106
    • Ishizuki, M.1    Yanagisawa, M.2
  • 36
    • 33644775732 scopus 로고    scopus 로고
    • Tinnitus retraining therapy: A different view on tinnitus
    • DOI 10.1159/000090487
    • Jastreboff PJ, Jastreboff MM: Tinnitus retraining therapy: a different view on tinnitus. ORL J Otorhinolaryngol Relat Spec 2006; 68: 23-29, discussion 29-30. (Pubitemid 43339681)
    • (2006) ORL , vol.68 , Issue.1 , pp. 23-29
    • Jastreboff, P.J.1    Jastreboff, M.M.2
  • 37
    • 0022407042 scopus 로고
    • The efferent projections from the reticular formation and the locus coeruleus studied by anterograde and retrograde axonal transport in the rat
    • DOI 10.1002/cne.902420105
    • Jones BE, Yang TZ: The efferent projections from the reticular formation and the locus coeruleus studied by anterograde and retrograde axonal transport in the rat. J Comp Neurol 1985; 242: 56-92. (Pubitemid 16202793)
    • (1985) Journal of Comparative Neurology , vol.242 , Issue.1 , pp. 56-92
    • Jones, B.E.1    Yang, T.-Z.2
  • 38
    • 33646862658 scopus 로고    scopus 로고
    • The dorsal cochlear nucleus as a participant in the auditory, attentional and emotional components of tinnitus
    • DOI 10.1016/j.heares.2006.01.002, PII S0378595506000037, The Cochlear Nucleus A tribute to Aage Moller
    • Kaltenbach JA: The dorsal cochlear nucleus as a participant in the auditory, attentional and emotional components of tinnitus. Hear Res 2006; 216-217: 224-234. (Pubitemid 43867183)
    • (2006) Hearing Research , vol.216-217 , Issue.1-2 , pp. 224-234
    • Kaltenbach, J.A.1
  • 39
    • 58749083949 scopus 로고    scopus 로고
    • Dorsal cochlear nucleus hyperactivity and tinnitus: Are they related?
    • Kaltenbach JA, Godfrey DA: Dorsal cochlear nucleus hyperactivity and tinnitus: are they related? Am J Audiol 2008; 17:S148-S161.
    • (2008) Am J Audiol , vol.17
    • Kaltenbach, J.A.1    Godfrey, D.A.2
  • 40
    • 25444447395 scopus 로고    scopus 로고
    • Involvement of supraspinal imidazoline receptors and descending monoaminergic pathways in tizanidine-induced inhibition of rat spinal reflexes
    • DOI 10.1254/jphs.FP0050520
    • Kino Y, Tanabe M, Honda M, Ono H: Involvement of supraspinal imidazoline receptors and descending monoaminergic pathways in tizanidine-induced inhibition of rat spinal reflexes. J Pharmacol Sci 2005; 99: 52-60. (Pubitemid 41366890)
    • (2005) Journal of Pharmacological Sciences , vol.99 , Issue.1 , pp. 52-60
    • Kino, Y.1    Tanabe, M.2    Honda, M.3    Ono, H.4
  • 42
    • 0030571009 scopus 로고    scopus 로고
    • Cyclobenzaprine, a centrally acting muscle relaxant, acts on descending serotonergic systems
    • DOI 10.1016/0014-2999(96)00402-5
    • Kobayashi H, Hasegawa Y, Ono H: Cyclobenzaprine, a centrally acting muscle relaxant, acts on descending serotonergic systems. Eur J Pharmacol 1996; 311: 29-35. (Pubitemid 26298496)
    • (1996) European Journal of Pharmacology , vol.311 , Issue.1 , pp. 29-35
    • Kobayashi, H.1    Hasegawa, Y.2    Ono, H.3
  • 46
    • 84859423962 scopus 로고    scopus 로고
    • Methodology of clinical trials for tinnitus
    • Moller A, Langguth B, De Ridder D, Kleinjung T (eds) New York, Springer
    • Landgrebe M, Langguth B, Zeman F, Koller M: Methodology of clinical trials for tinnitus; in Moller A, Langguth B, De Ridder D, Kleinjung T (eds): Textbook of Tinnitus. New York, Springer, 2011a, pp 199-212.
    • (2011) Textbook of Tinnitus , pp. 199-212
    • Landgrebe, M.1    Langguth, B.2    Zeman, F.3    Koller, M.4
  • 47
    • 77955106753 scopus 로고    scopus 로고
    • The Tinnitus Research Initiative (TRI) database: A new approach for delineation of tinnitus subtypes and generation of predictors for treatment outcome
    • Landgrebe M, Zeman F, Koller M, Eberl Y, Mohr M, Reiter J, Staudinger S, Hajak G, Langguth B: The Tinnitus Research Initiative (TRI) database: a new approach for delineation of tinnitus subtypes and generation of predictors for treatment outcome. BMC Med Inform Decis Mak 2011b;10: 42.
    • (2011) BMC Med Inform Decis Mak , vol.10 , pp. 42
    • Landgrebe, M.1    Zeman, F.2    Koller, M.3    Eberl, Y.4    Mohr, M.5    Reiter, J.6    Staudinger, S.7    Hajak, G.8    Langguth, B.9
  • 48
    • 79958187014 scopus 로고    scopus 로고
    • Time to recovery in patients with acute painful musculoskeletal conditions treated with extended-release or immediate-release cyclobenzaprine
    • Landy S, Altman CA, Xie F: Time to recovery in patients with acute painful musculoskeletal conditions treated with extended-release or immediate-release cyclobenzaprine. Adv Ther 2011; 28: 295-303.
    • (2011) Adv Ther , vol.28 , pp. 295-303
    • Landy, S.1    Altman, C.A.2    Xie, F.3
  • 54
    • 0346158381 scopus 로고    scopus 로고
    • CNS somatosensory-auditory interactions elicit or modulate tinnitus
    • DOI 10.1007/s00221-003-1747-3
    • Levine RA, Abel M, Cheng H: CNS somatosensory-auditory interactions elicit or modulate tinnitus. Exp Brain Res 2003; 153: 643-648. (Pubitemid 38030855)
    • (2003) Experimental Brain Research , vol.153 , Issue.4 , pp. 643-648
    • Levine, R.A.1    Abel, M.2    Cheng, H.3
  • 55
    • 0035293145 scopus 로고    scopus 로고
    • Cyclobenzaprine hydrochloride is a commonly prescribed centrally acting muscle relaxant, which is structurally similar to tricyclic antidepressants (TCAs) and differs from amitriptyline by only one double bond
    • Lofland JH, Szarlej D, Buttaro T, Shermock S, Jalali S: Cyclobenzaprine hydrochloride is a commonly prescribed centrally acting muscle relaxant, which is structurally similar to tricyclic antidepressants (TCAs) and differs from amitriptyline by only one double bond. Clin J Pain 2001; 17: 103-104.
    • (2001) Clin J Pain , vol.17 , pp. 103-104
    • Lofland, J.H.1    Szarlej, D.2    Buttaro, T.3    Shermock, S.4    Jalali, S.5
  • 56
    • 67649392373 scopus 로고    scopus 로고
    • Cyclobenzaprine ER for muscle spasm associated with low back and neck pain: Two randomized, doubleblind, placebo-controlled studies of identical design
    • Malanga GA, Ruoff GE, Weil AJ, Altman CA, Xie F, Borenstein DG: Cyclobenzaprine ER for muscle spasm associated with low back and neck pain: two randomized, doubleblind, placebo-controlled studies of identical design. Curr Med Res Opin 2009; 25: 1179-1196.
    • (2009) Curr Med Res Opin , vol.25 , pp. 1179-1196
    • Malanga, G.A.1    Ruoff, G.E.2    Weil, A.J.3    Altman, C.A.4    Xie, F.5    Borenstein, D.G.6
  • 57
    • 78649578071 scopus 로고    scopus 로고
    • The more the worse: The grade of noise-induced hearing loss associates with the severity of tinnitus
    • Mazurek B, Olze H, Haupt H, Szczepek AJ: The more the worse: the grade of noise-induced hearing loss associates with the severity of tinnitus. Int J Environ Res Public Health 2010; 7: 3071-3079.
    • (2010) Int J Environ Res Public Health , vol.7 , pp. 3071-3079
    • Mazurek, B.1    Olze, H.2    Haupt, H.3    Szczepek, A.J.4
  • 58
    • 0033975197 scopus 로고    scopus 로고
    • Lateralized tinnitus studied with functional magnetic resonance imaging: Abnormal inferior colliculus activation
    • Melcher JR, Sigalovsky IS, Guinan JJ Jr, Levine RA: Lateralized tinnitus studied with functional magnetic resonance imaging: abnormal inferior colliculus activation. J Neurophysiol 2000; 83: 1058-1072. (Pubitemid 30091313)
    • (2000) Journal of Neurophysiology , vol.83 , Issue.2 , pp. 1058-1072
    • Melcher, J.R.1    Sigalovsky, I.S.2    Guinan Jr., J.J.3    Levine, R.A.4
  • 60
    • 35348921250 scopus 로고    scopus 로고
    • Tinnitus: Presence and future
    • DOI 10.1016/S0079-6123(07)66001-4, PII S0079612307660014, Tinnitus: Pathophysiology and Treatment
    • Moller AR: Tinnitus: presence and future. Prog Brain Res 2007a;166: 3-16. (Pubitemid 47588055)
    • (2007) Progress in Brain Research , vol.166 , pp. 3-16
    • Moller, A.R.1
  • 61
    • 35348926965 scopus 로고    scopus 로고
    • Tinnitus and pain
    • DOI 10.1016/S0079-6123(07)66004-X, PII S007961230766004X, Tinnitus: Pathophysiology and Treatment
    • Moller AR: Tinnitus and pain. Prog Brain Res 2007b;166: 47-53. (Pubitemid 47588058)
    • (2007) Progress in Brain Research , vol.166 , pp. 47-53
    • Moller, A.R.1
  • 62
    • 0037039826 scopus 로고    scopus 로고
    • The non-classical auditory pathways are involved in hearing in children but not in adults
    • DOI 10.1016/S0304-3940(01)02516-2, PII S0304394001025162
    • Moller AR, Rollins PR: The non-classical auditory pathways are involved in hearing in children but not in adults. Neurosci Lett 2002; 319: 41-44. (Pubitemid 34117639)
    • (2002) Neuroscience Letters , vol.319 , Issue.1 , pp. 41-44
    • Moller, A.R.1    Rollins, P.R.2
  • 64
    • 14944341738 scopus 로고    scopus 로고
    • 1 receptor antagonists in two functional models
    • DOI 10.1016/j.ejphar.2004.11.006, PII S0014299904012622
    • Orzechowski RF, Currie DS, Valancius CA: Comparative anticholinergic activities of 10 histamine H 1 receptor antagonists in two functional models. Eur J Pharmacol 2005; 506: 257-264. (Pubitemid 41071398)
    • (2005) European Journal of Pharmacology , vol.506 , Issue.3 , pp. 257-264
    • Orzechowski, R.F.1    Currie, D.S.2    Valancius, C.A.3
  • 67
    • 3042588399 scopus 로고    scopus 로고
    • Activation of monkey locus coeruleus neurons varies with difficulty and performance in a target detection task
    • DOI 10.1152/jn.00673.2003
    • Rajkowski J, Majczynski H, Clayton E, Aston-Jones G: Activation of monkey locus coeruleus neurons varies with difficulty and performance in a target detection task. J Neurophysiol 2004; 92: 361-371. (Pubitemid 38802258)
    • (2004) Journal of Neurophysiology , vol.92 , Issue.1 , pp. 361-371
    • Rajkowski, J.1    Majczynski, H.2    Clayton, E.3    Aston-Jones, G.4
  • 68
    • 35348955938 scopus 로고    scopus 로고
    • Myofascial trigger points: Another way of modulating tinnitus
    • DOI 10.1016/S0079-6123(07)66018-X, PII S007961230766018X, Tinnitus: Pathophysiology and Treatment
    • Rocha CA, Sanchez TG: Myofascial trigger points: another way of modulating tinnitus. Prog Brain Res 2007; 166: 209-214. (Pubitemid 47595308)
    • (2007) Progress in Brain Research , vol.166 , pp. 209-214
    • Rocha, C.A.C.B.1    Sanchez, T.G.2
  • 69
    • 0027343018 scopus 로고
    • Tinnitus and craniomandibular disorders -Is there a link?
    • Rubinstein B: Tinnitus and craniomandibular disorders -is there a link? Swed Dent J Suppl 1993; 95: 1-46.
    • (1993) Swed Dent J Suppl , vol.95 , pp. 1-46
    • Rubinstein, B.1
  • 73
    • 0018833952 scopus 로고
    • The pharmacology of 5-chloro-4-(2-imidazolin-2-yl-amino)-2,1,3- benzothiadiazole (DS 103-282), a novel myotonolytic agent
    • Sayers AC, Burki HR, Eichenberger E: The pharmacology of 5-chloro-4-(2-imidazolin-2-yl-amino)-2,1,3-benzothiadiazole (DS 103-282), a novel myotonolytic agent. Arzneimittelforschung 1980; 30: 793-803. (Pubitemid 10107317)
    • (1980) Arzneimittel-Forschung/Drug Research , vol.30 , Issue.5 , pp. 793-803
    • Sayers, A.C.1    Burki, H.R.2    Eichenberger, E.3
  • 74
    • 61649098811 scopus 로고    scopus 로고
    • Abnormal resting-state cortical coupling in chronic tinnitus
    • Schlee W, Hartmann T, Langguth B, Weisz N: Abnormal resting-state cortical coupling in chronic tinnitus. BMC Neurosci 2009a;10: 11.
    • (2009) BMC Neurosci , vol.10 , pp. 11
    • Schlee, W.1    Hartmann, T.2    Langguth, B.3    Weisz, N.4
  • 76
    • 56649103587 scopus 로고    scopus 로고
    • Using auditory steady state responses to outline the functional connectivity in the tinnitus brain
    • Schlee W, Weisz N, Bertrand O, Hartmann T, Elbert T: Using auditory steady state responses to outline the functional connectivity in the tinnitus brain. PLoS One 2008; 3:e3720.
    • (2008) PLoS One , vol.3
    • Schlee, W.1    Weisz, N.2    Bertrand, O.3    Hartmann, T.4    Elbert, T.5
  • 77
    • 0034041517 scopus 로고    scopus 로고
    • A review of evidence in support of a role for 5-HT in the perception of tinnitus
    • DOI 10.1016/S0378-5955(00)00093-9, PII S0378595500000939
    • Simpson JJ, Davies WE: A review of evidence in support of a role for 5-HT in the perception of tinnitus. Hear Res 2000; 145: 1-7. (Pubitemid 30365261)
    • (2000) Hearing Research , vol.145 , Issue.1-2 , pp. 1-7
    • Simpson, J.J.1    Davies, W.E.2
  • 78
    • 34547491663 scopus 로고    scopus 로고
    • Lateralization of functional magnetic resonance imaging (fMRI) activation in the auditory pathway of patients with lateralized tinnitus
    • DOI 10.1007/s00234-007-0231-3
    • Smits M, Kovacs S, de Ridder D, Peeters RR, van Hecke P, Sunaert S: Lateralization of functional magnetic resonance imaging (fMRI) activation in the auditory pathway of patients with lateralized tinnitus. Neuroradiology 2007; 49: 669-679. (Pubitemid 47163357)
    • (2007) Neuroradiology , vol.49 , Issue.8 , pp. 669-679
    • Smits, M.1    Kovacs, S.2    De Ridder, D.3    Peeters, R.R.4    Van Hecke, P.5    Sunaert, S.6
  • 79
    • 0027517875 scopus 로고
    • A randomized trial of nortriptyline for severe chronic tinnitus: Effects on depression, disability, and tinnitus symptoms
    • DOI 10.1001/archinte.153.19.2251
    • Sullivan M, Katon W, Russo J, Dobie R, Sakai C: A randomized trial of nortriptyline for severe chronic tinnitus. Effects on depression, disability, and tinnitus symptoms. Arch Intern Med 1993; 153: 2251-2259. (Pubitemid 23296492)
    • (1993) Archives of Internal Medicine , vol.153 , Issue.19 , pp. 2251-2259
    • Sullivan, M.1    Katon, W.2    Russo, J.3    Dobie, R.4    Sakai, C.5
  • 80
    • 0028854170 scopus 로고
    • Distribution and origin of serotoninergic afferents to guinea pig cochlear nucleus
    • Thompson AM, Moore KR, Thompson GC: Distribution and origin of serotoninergic afferents to guinea pig cochlear nucleus. J Comp Neurol 1995; 351: 104-116.
    • (1995) J Comp Neurol , vol.351 , pp. 104-116
    • Thompson, A.M.1    Moore, K.R.2    Thompson, G.C.3
  • 82
    • 26244437991 scopus 로고    scopus 로고
    • Hearing loss and tinnitus: 250 Million people and a US$10 billion potential market
    • DOI 10.1016/S1359-6446(05)03594-4, PII S1359644605035944
    • Vio MM, Holme RH: Hearing loss and tinnitus: 250 million people and a US$10 billion potential market. Drug Discov Today 2005; 10: 1263-1265. (Pubitemid 41416695)
    • (2005) Drug Discovery Today , vol.10 , Issue.19 , pp. 1263-1265
    • Vio, M.M.1    Holme, R.H.2
  • 83
    • 33748511911 scopus 로고    scopus 로고
    • Scopolamine attenuates tinnitus-related plasticity in the auditory cortex
    • DOI 10.1097/01.wnr.0000230504.25102.26, PII 0000175620061002000006
    • Wallhausser-Franke E, Cuautle-Heck B, Wenz G, Langner G, Mahlke C: Scopolamine attenuates tinnitus-related plasticity in the auditory cortex. Neuroreport 2006; 17: 1487-1491. (Pubitemid 44359458)
    • (2006) NeuroReport , vol.17 , Issue.14 , pp. 1487-1491
    • Wallhausser-Franke, E.1    Cuautle-Heck, B.2    Wenz, G.3    Langner, G.4    Mahlke, C.5
  • 84
    • 0033050707 scopus 로고    scopus 로고
    • Central anticholinergic syndrome on therapeutic doses of cyproheptadine
    • DOI 10.1542/peds.103.1.158
    • Watemberg NM, Roth KS, Alehan FK, Epstein CE: Central anticholinergic syndrome on therapeutic doses of cyproheptadine. Pediatrics 1999; 103: 158-160. (Pubitemid 29281945)
    • (1999) Pediatrics , vol.103 , Issue.1 , pp. 158-160
    • Watemberg, N.M.1    Roth, K.S.2    Alehan, F.K.3    Epstein, C.E.4
  • 85
    • 0029974155 scopus 로고    scopus 로고
    • A double-blind placebo-controlled trial of baclofen in the treatment of tinnitus
    • Westerberg BD, Roberson JB Jr, Stach BA: A double-blind placebo-controlled trial of baclofen in the treatment of tinnitus. Am J Otol 1996; 17: 896-903. (Pubitemid 26379254)
    • (1996) American Journal of Otology , vol.17 , Issue.6 , pp. 896-903
    • Westerberg, B.D.1    Roberson Jr., J.B.2    Stach, B.A.3
  • 86
    • 0029878615 scopus 로고    scopus 로고
    • 2-receptor antagonists containing diphenhydramine and cyproheptadine derivatives
    • DOI 10.1002/ardp.19963290206
    • Wolf C, Schunack W: Synthesis and pharmacology of combined histamine H 1 -/H 2 -receptor antagonists containing diphenhydramine and cyproheptadine derivatives. Arch Pharm (Weinheim) 1996; 329: 87-94. (Pubitemid 26081742)
    • (1996) Archiv der Pharmazie , vol.329 , Issue.2 , pp. 87-94
    • Wolf, C.1    Schunack, W.2
  • 89
    • 10644273487 scopus 로고    scopus 로고
    • Projections from the trigeminal nuclear complex to the cochlear nuclei: A retrograde and anterograde tracing study in the guinea pig
    • DOI 10.1002/jnr.20343
    • Zhou J, Shore S: Projections from the trigeminal nuclear complex to the cochlear nuclei: a retrograde and anterograde tracing study in the guinea pig. J Neurosci Res 2004; 78: 901-907. (Pubitemid 39657577)
    • (2004) Journal of Neuroscience Research , vol.78 , Issue.6 , pp. 901-907
    • Zhou, J.1    Shore, S.2


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