Lateralized tinnitus studied with functional magnetic resonance imaging: Abnormal inferior colliculus activation

Journal of Neurophysiology

Volumn 83, Issue 2, 2000, Pages 1058-1072

  Melcher, J R ^a,b,c   Sigalovsky, I S ^a,c   Guinan Jr , J J ^a,b,c   Levine, R A ^a,b,c,d  

^a MASSACHUSETTS EYE AND EAR INFIRMARY   (United States)

^b HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; INFERIOR COLLICULUS; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; TINNITUS;

EID: 0033975197     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.2000.83.2.1058     Document Type: Article

References (119)

1. ADAMS, J. C. Ascending projections to the inferior colliculus. J. Comp. Neurol. 183: 519-538, 1979.
2. 18F]deoxyglucose. Otorhinolaryngol. (Basel) 58: 195-199, 1996.
3. ATTIAS, J., BRESLOFF, I., AND FURMAN, V. The influence of the efferent auditory system on otoacoustic emissions in noise induced tinnitus: clinical relevance. Acta Otolaryngol. 116: 534-539, 1996a.
4. ATTIAS, J., FURMAN, V., SHEMESH, Z., AND BRESLOFF, I. Impaired brain processing in noise-induced tinnitus patients as measured by auditory and visual event-related potentials. Ear Hear. 17: 327-333, 1996b.
5. ATTIAS, J., URBACH, D., GOLD, S., AND SHEMESH, Z. Auditory event related potentials in chronic tinnitus patients with noise induced hearing loss. Hear. Res. 71: 106-113, 1993.
6. BANDETTINI, P. A., JESMANOWICZ, A., VAN KYLEN, J., BIRN, R. M., AND HYDE, J. S. Functional MRI of brain activation induced by scanner acoustic noise. Magn. Reson. Med. 39: 410-416, 1998.
7. BANDETTINI, P. A., WONG, E. C., HINKS, R. S., TIKOFSKY, R. S., AND HYDE, J. S. Time course EPI of human brain function during task activation. Magn. Reson. Med. 25: 390-397, 1992.
8. BARINAGA, M. fMRI provides new view of monkey brains. Science 282: 1397, 1998.
9. BARNEA G., ATTIAS, J., GOLD, S., AND SHAHAR, A. Tinnitus with normal hearing sensitivity: extended high-frequency audiometry and auditory-nerve brain-stem-evoked responses. Audiology 29: 36-45, 1990.
10. CACACE, A. T. Imaging tinnitus with fMRI. Assoc. Res. Otolaryngol. Abstr. 20: 2, 1997.
11. CACACE, A. T., COUSINS, J. P., MOONEN, C.T.W., VAN GELDEREN, P., MILLER, D., PARNES, S. M., AND LOVELY, T. J. In-vivo localization of phantom auditory perceptions during functional magnetic resonance imaging of the human brain. In: Proceedings of the Fifth International Tinnitus Seminar, edited by G. E. Reich and J. A. Vernon. Portland, OR: Am. Tinnitus Assoc., 1996, p. 397-401.
12. CACACE, A. T., COUSINS, J. P., PARNES, S. M., SEMENOFF, D., HOLMES, T., MCFARLAND, D. J., DAVENPORT, C., STEGBAUER, K., AND LOVELY, T. J. Cutaneous-evoked tinnitus. Audiol. Neurootol. 4: 247-257, 1999.
13. CACACE, A. T., LOVELY, T. J., MCFARLAND, D. J., PARNES, S. M., AND WINTER, D. F. Anomalous cross-modal plasticity following posterior fossa surgery: some speculations on gaze-evoked tinnitus. Hear. Res. 81: 22-32, 1994.
14. CAZALS, Y., HORNER, K. C., AND HUANG, Z. W. Alterations in average spectrum of cochleoneural activity by long-term salicylate treatment in the guinea pig: a plausible index of tinnitus. J. Neurophysiol. 80: 2113-2120, 1998.
15. CHEN, G. AND JASTREBOFF, P. J. Salicylate-induced abnormal activity in the inferior colliculus of rats. Hear. Res. 82: 158-178, 1995.
16. CHÉRY-CROZE, S., COLLET, L., AND MORGON, A. Medial olivo-cochlear system and tinnitus. Acta Otolaryngol. 113: 285-290, 1993.
17. CHOLE, R. A. AND PARKER, W. S. Tinnitus and vertigo in patients with temporomandibular disorder. Arch. Otolaryngl. Head Neck Surg. 118: 817-821, 1992.
18. CLAUSSEN, C. F. AND CONSTANTINESCU, L. Tinnitus in whiplash injury. Int. Tinnitus J. 1: 105-114, 1995.
19. COATS, A. C. AND MARTIN, J. L. Human auditory nerve action potentials and brain stem evoked responses. Arch. Otolaryngol. 103: 605-622, 1977.
20. COHEN, M. S. Echo-planar imaging and functional MRI. In: Functional MRI, edited by C.T.W. Moonen and P. A. Bandettini. Berlin: Springer-Verlag, 1999, p. 137-148.
21. COLDING-JØRGENSEN, E., LAURITZEN, M., JOHNSEN, N. J., MIKKELSEN, K. B., AND SÆRMARK, K. On the evidence of auditory evoked magnetic fields as an objective measure of tinnitus. Electroencephalogr. Clin. Neurophysiol. 83: 322-327, 1992.
22. COLES, R.R.A. Epidemiology of tinnitus. I. Prevalence. J. Laryngol. Otol. 9, Suppl.: 7-15, 1984a.
23. COLES, R.R.A. Epidemiology of tinnitus. II. Demographic and clinical features. J Laryngol. Otol. 9, Suppl.: 195-202, 1984b.
24. DAVID, A. S., WOODRUFF, P.W.R., HOWARD, R., MELLERS, J.D.C., BRAMMER, M., BULLMORE, E., WRIGHT, I., ANDREW, C., AND WILLIAMS, S.C.R. Auditory hallucinations inhibit exogenous activation of auditory association cortex. Neuroreport. 7: 932-936, 1996.
25. DOUEK, E. AND REID, J. The diagnostic value of tinnitus pitch. J. Laryngol. Otol. 82: 1039-1042, 1969.
26. DUBOWITZ, D. J., CHEN, D.-Y., ATKINSON, D. J., GRIEVE, K. L., GILLIKIN, B., BRADLEY, W. G., JR., AND ANDERSEN, R. A. Functional magnetic resonance imaging in macaque cortex. Neuroreport. 9: 2213-2218, 1998, 1998.
27. EDMISTER, W. B., TALAVAGE, T. M., LEDDEN, P. J., AND WEISSKOFF, R. M. Improved auditory cortex imaging using clustered volume acquisitions. Hum. Brain Mapp. 7: 89-97, 1999.
28. EGGERMONT, J. J. On the pathophysiology of tinnitus; a review and a peripheral model. Hear. Res. 48: 111-124, 1990.
29. EGGERMONT, J. J. AND KENMOCHI, M. Salicylate and quinine selectively increase spontaneous firing rates in secondary auditory cortex. Hear. Res. 117: 149-160, 1998.
30. EVANS, E. F. AND BORERWE, T. A. Ototoxic effects of salicylates on the responses of single cochlear nerve fibres and on cochlear potentials. Br. J. Audiol. 16: 101-108, 1982.
31. EVANS, E. F., WILSON, J. P., AND BORERWE, T. A. Animal models of tinnitus. In: Tinnitus, Ciba Foundation Symposium 85, edited by D. Evered and G. Lawrenson. London: Pitman Books Ltd., 1981, p. 108-138.
32. FELDMANN, H. Homolateral and contralateral masking of tinnitus by noise-bands and by pure tones. Audiology 10: 138-144, 1971.
33. FELDMANN, H. Time patterns and related parameters in masking of tinnitus. Acta Otolaryngol. 95: 594-598, 1983.
34. FOWLER, E. P. Head noises in normal and in disordered ears. Arch. Otolaryngol. 39: 498-503, 1944.
35. FOWLER, E. P. Control of head noises. Arch. Otolaryngol. 37: 391-398, 1948.
36. FOX, P. T. AND RAICHLE, M. E. Focal physiological uncoupling of cerebral blood flow and oxidaive metabolism during somatosensory stimulation in human subjects. Proc. Natl. Acad. Sci. USA 83: 1140-1144, 1986.
37. FOX, P. T., RAICHLE, M. E., MINTUN, M. A., AND DENCE, C. Nonoxidative glucose consumption during focal physiologic neural activity. Science 241: 462-464, 1988.
38. FRISTON, K. J., ASHBURNER, J., FRITH, C. D., POLINE, J. B., HEATHER, J. D., AND FRACKOWIAK, R.S.J. Spatial registration and normalization of images. Hum. Brain Mapp. 2: 165-189, 1995.
39. GIRAUD, A. L., CHÉRY-CROZE, S., FISCHER, G., FISCHER, C., VIGHETTO, A., GREGOIRE, M.-C., LAVENNE, F., AND COLLET, L. A selective imaging of tinnitus. Neuroreport 10: 1-5, 1999.
40. GUIMARAES, A. R., MELCHER, J. R., TALAVAGE, T. M., BAKER, J. R., LEDDEN, P., ROSEN, B. R., KIANG, N.Y.S., FULLERTON, B. C., AND WEISSKOFF, R. M. Imaging subcortical auditory activity in humans. Hum. Brain Mapp. 6: 33-41, 1998.
41. HALL, D. A., HAGGARD, M. P., AKEROYD, M. A., PALMER, A. R., SUMMERFIELD, A. Q., ELLIOTT, M. R., GURNEY, E. M., AND BOWTELL, R. W. "Sparse" temporal sampling in auditory fMRI. Hum. Brain Mapp. 7: 213-223, 1999.
42. HOKE, M., FELDMANN, H., PANTEV, C., LÜTKENHÖNER, B., AND LEHNERTZ, K. Objective evidence of tinnitus in auditory evoked magnetic fields. Hear. Res. 37: 281-286, 1989.
43. HOKE, M., PANTEV, C., LÜTKENHÖNER, B., AND LEHNERTZ, K. Auditory cortical basis of tinnitus. Acta Otolaryngol. Suppl. 491: 176-182, 1991.
44. HOUSE, J. W. AND BRACKMANN, D. E. Tinnitus: surgical treatment. In: Tinnitus, Ciba Foundation Symposium 85, edited by D. Evered and G. Lawrenson. London: Pitman Books Ltd., 1981, p. 204-216.
45. 200) measurements in tinnitus and normal groups. Hear. Res. 56: 44-52, 1991.
46. JACOBSON, G. P., AHMAD, B. K., MORAN, J., NEWMAN, C. W., WHARTON, J., AND TEPLEY, N. Auditory evoked field (M100-M200) measurements in tinnitus and normal groups. In: Tinnitus 91, Proceedings of the Fourth International Tinnitus Seminar, edited by J. M. Aran and R. Dauman. Amsterdam: Kugler Publications, 1992, p. 317-322.
47. JANSSEN, T., KUMMER, P., AND ARNOLD, W. Growth behavior of the 2f1-f2 distortion product otoacoustic emission in tinnitus. J. Acoust. Soc. Am. 103: 3418-3430, 1998.
48. JASTREBOFF, M. M. AND JASTREBOFF, P. J. Tinnitus-related modulation of c-fos expression. In: Proceedings of the Fifth International Tinnitus Seminar, edited by G. E. Reich and J. A. Vernon. Portland, OR: Am. Tinnitus Assoc., 1996, p. 426-428.
49. JASTREBOFF, P. J., BRENNAN, J. F., COLEMAN, J. K., AND SASAKI, C. T. Phantom auditory sensation in rats: an animal model for tinnitus. Behav. Neurosci. 102: 811-822, 1988.
50. JASTREBOFF, P. J. AND SASAKI, C. T. Salicylate-induced changes in spontaneous activity of single units in the inferior colliculus of the guinea pig. J. Acoust. Soc. Am. 80: 1384-1391, 1986.
51. JASTREBOFF, P. J. AND SASAKI, C. T. An animal model of tinnitus: a decade of development. Am. J. Otol. 15: 19-27, 1994.
52. JEZZARD, P., RAUSCHECKER, J. P., AND MALONEK, D. An in vivo model for functional MRI in cat visual cortex. Magn. Reson. Med. 38: 699-705, 1997.
53. KALTENBACH, J. A., GODFREY, D. A., NEUMANN, J. B., MCCASLIN, D. L., AFMAN, C. E., AND ZHANG, J. Changes in spontaneous neural activity in the dorsal cochlear nucleus following exposure to intense sound: relation to threshold shift. Hear. Res. 124: 78-84, 1998.
54. KALTENBACH, J. A. AND HEFFNER, H. E. Spontaneous activity in the dorsal cochlear nucleus of hamsters tested behaviorally for tinnitus. Assoc. Res. Otolaryngol. Abstr. 22: 47, 1999.
55. KALTENBACH, J. A. AND MCCASLIN, D. L. Increases in spontaneous activity in the dorsal cochlear nucleus following exposure to high intensity sound: a possible neural correlate of tinnitus. Aud. Neurosci. 3: 57-78, 1996.
56. KAUER, J. S., NEMITZ, J. W., AND SASAKI, C. T. Tinnitus aurium: fact .. or fancy. Laryngoscope 92: 1401-1407, 1982.
57. KIANG, N.Y.S., FULLERTON, B. C., RICHTER, E. A., LEVINE, R. A., AND NORRIS, B. E. Artificial stimulation of the auditory system. Adv. Audiol. 1: 6-17, 1984.
58. KIANG, N.Y.S., MOXON, E. C., AND LEVINE, R. A. Auditory-nerve activity in cats with normal and abnormal cochleas. In: Sensorineural Hearing Loss, A Ciba Foundation Symposium, edited by G. E. Wolstenholme and J. Knight. London: J&A Churchill, 1970, p. 241-273.
59. KWONG, K. K., BELLIVEAU, J. W., CHESLEK, D. A., GOLDBERG, I. E., WEISSKOFF, R. M., PONCELET, B. P., KENNEDY, D. N., HOPPEL, B. E., COHEN, M. S., TURNER, R., CHENG, H.-M., BRADY, T. J., AND ROSEN, B. R. Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. Proc. Nat. Acad. Sci. USA 89: 5675-5679, 1992.
60. LESKE, M. C. Prevalence estimates of communicative disorders in the U. S. J. Am. Speech Hear. Assoc. 23: 229-237, 1981.
61. LEVINE, R. A. Somatic modulation appears to be a fundamental attribute of tinnitus. In: Proceedings of the Sixth International Tinnitus Seminar, edited by J. Hazell. Cambridge, UK: Cambridge Univ. Press, 1999, p. 193-197.
62. LEVINE, R. A., BENSON, R. R., TALAVAGE, T. M., MELCHER, J. R., ROSEN, B. R. Functional magnetic resonance imaging and tinnitus: preliminary results. Assoc. Res. Otolaryngol. Abstr. 20: 65, 1997.
63. LEVINE, R. A. AND KIANG, N.Y.S. A conversation about tinnitus. In: Mechanisms of Tinnitus, edited by J. A. Vernon and A. R. Møller. Boston: Allyn and Bacon, 1995, p. 149-161.
64. LOCKWOOD, A. H., BURKARD, R. F., SALVI, R. J., ARNOLD, S. A., REYES, S. A., COAD, M. L., LINCOFF, N. S., GALANTOWICZ, P. J., AND WACK, D. S. Positron emission tomographic (PET) studies of gaze-evoked tinnitus (Abstract). Assoc. Res. Otolaryngol. 22: 119, 1999.
65. LOCKWOOD, A. H., SALVI, R. J., COAD, M. L., TOWSLEY, M. L., WACK, D. S., AND MURPHY, B. W. The functional neuroanatomy of tinnitus. Evidence for limbic system links and neural plasticity. Neurology 50: 114-120, 1998.
66. LOGOTHETIS, N. K., PELED, S., AND PAULS, J. Development and application of fMRI for visual studies in monkeys. Soc. Neurosci. Abstr. 24: 11, 1998.
67. MANABE, Y., YOSHIDA, S., SAITO, H., AND OKA, H. Effects of lidocaine on salicylate-induced discharge of neurons in the inferior colliculus of the guinea pig. Hear. Res. 103: 192-198, 1997.
68. MANDEVILLE, J. B., MAROTA, J. J., KOSOFSKY, B. E., KELTNER, J. R., WEISSLEDER, R., ROSEN, B. R., AND WEISSKOFF, R. M. Dynamic functional imaging of relative cerebral blood volume during rat forepaw stimulation. Magn. Reson. Med. 39: 615-624, 1998.
69. MARTIN, W. H., SCHWEGLER, J. W., SCHEIBELHOFFER, J., AND RONIS, M. L. Salicylate-induced changes in cat auditory nerve activity. Laryngoscope 103: 600-604, 1993.
70. MARTIN, W. H., SCHWEGLER, J. W., SHI, Y.-B., PRATT, H., AND ADLER, S. Developing an objective measurement tool for evaluating tinnitus: spectral averaging. In: Proceedings of the Fifth International Tinnitus Seminar, edited by G. E. Reich and J. A. Vernon. Portland, OR: Am. Tinnitus. Assoc., 1996, p. 127-134.
71. MAURIZI M., OTTAVIANI F., PALUDETTI G., ALMADORI G., AND TASSONI A. Contribution to the differentiation of peripheral versus central tinnitus via auditory brain stem response evaluation. Audiology 24: 207-216, 1985.
72. MCKEE, J. AND STEPHANS, D. G. An investigation of normally hearing subjects with tinnitus. Audiology 31: 313-317, 1992.
73. MEIKLE, M. AND GRIEST, S. The perceived localization of tinnitus. In: Proceedings of the Third International Tinnitus Seminar, edited by H. Feldmann. Germany: Harsch Verlag Karlsruhe, 1987, p. 183-189.
74. MEIKLE, M. B., GRIEST, S. E., PRESS, L. S., AND STEWART, B. J. Relationships between tinnitus and audiometric variables in a large sample of tinnitus clinic patients. In: Tinnitus 91, edited by J.-M. Aran and R. Dauman. New York: Kugler Publications, 1992, p. 27-34.
75. MEIKLE, M., SCHUFF, N., AND GRIEST, S. Intra-subject variability of tinnitus: observations from the tinnitus clinic. In: Proceedings of the Third International Tinnitus Seminar, edited by H. Feldmann. Germany: Harsch Verlag Karlsruhe, 1987, p. 175-180.
76. MEIKLE, M. AND TAYLOR-WALSH, E. Characteristics of tinnitus and related observations in over 1800 tinnitus clinic patients. J. Laryngol. Otol. 9, Suppl.: 17-21, 1984.
77. MELCHER, J. R., FULLERTON, B. C., AND WEISSKOFF, R. M. Imaging human auditory function from brainstem to cortex (Abstract). Neuroimage 5: S172, 1997.
78. MELCHER, J. R., TALAVAGE, T. M., AND HARMS, M. P. Functional MRI of the auditory system. In: Functional MRI, edited by C.T.W. Moonen and P. A. Bandettini. Berlin: Springer-Verlag, 1999, p. 393-406.
79. MIRZ, F., PEDERSEN, C. B., ISHIZU, K., JOHANNSEN, P., OVESEN, T., STØDKILDE-JØRGENSEN, H. AND GJEDDE, A. Positron emission tomography of cortical centers of tinnitus. Hear. Res. 134: 133-144, 1999.
80. MØLLER, A. R. Pathophysiology of tinnitus. In: Mechanisms of Tinnitus, edited by J. A. Vernon and A. R. Møller. Boston: Allyn and Bacon, 1995, p. 207-217.
81. MØLLER, A. R., MØLLER, M. B., AND YOKOTA, M. Some forms of tinnitus may involve the extralemniscal auditory pathway. Laryngoscope 102: 1165-1171, 1992.
82. MONGAN, E., KELLY, P., NIES, K., PORTER, W. W., AND PAULUS, H. E. Tinnitus as an indication of theraputic serum salicylate levels. JAMA 226: 142-145, 1973.
83. MÜHLNICKEL, W., ELBERT, T., TAUB, E., AND FLOR, H. Reorganization of auditory cortex in tinnitus. Proc. Natl. Acad. Sci. USA 95: 10340-10343, 1998.
84. 14C]2-deoxyglucose labeling of synaptic activity in the central auditory system. J. Comp. Neurol. 245: 553-565, 1986.
85. OCHI, K. AND EGGERMONT, J. J. Effects of salicylate on neural activity in cat primary auditory cortex. Hear. Res. 95: 63-76, 1996.
86. OGAWA, S., TANK, D. W., MENON, R., ELLERMANN, J. M., KIM, S.-G., MERKLE, H., AND UGURBIL, K. Intrinsic signal changes accompanying sensory stimulation: functional brain mapping with magnetic resonance imaging. Proc. Nat. Acad. Sci. USA 89: 5951-5955, 1992.
87. OSEN, K. K. Projection of the cochlear nuclei on the inferior colliculus in the cat. J. Comp. Neurol. 144: 355-371, 1972.
88. PANTEV, C., HOKE, M., LÜTKENHÖNER, B., LEHNERTZ, K., AND KUMPF, W. Tinnitus remission objectified by neuromagnetic measurements. Hear. Res. 40: 261-264, 1989.
89. PENNER, M. J. An estimate of the prevalence of tinnitus caused by spontaneous otoacoustic emissions. Arch. Otolaryngol. Head Neck Surg. 116: 418-423, 1990.
90. PENNER, M. J., BRAUTH, S., AND HOOD, L. The temporal course of the masking of tinnitus as a basis for inferring its origin. J. Speech Hear. Res. 24: 257-261, 1981.
91. PETTIGREW, A. M., LIBERMAN, M. C., AND KIANG, N.Y.S. Click-evoked gross potentials and single-unit thresholds in acoustically traumatized cats. Ann. Otol. Rhino. Laryngol. 112, Suppl. 93: 83-95, 1984.
92. PINCHOFF, R. J., BURKARD, R. F., SALVI, R. J., COAD, M. L., AND LOCKWOOD, A. H. Modulation of tinnitus by voluntary jaw movement. Am. J. Otol. 19: 785-789, 1998.
93. PROSHANSKY, E., KAUER, J. S., STEWART, W. B., AND EGGER, D. 2-deoxyglucose uptake in the cat spinal cord during sustained and habituated activity in the plantar cushion reflex pathway. J. Comp. Neurol. 194: 505-517, 1980.
94. PULEC, J. L. Cochlear nerve section for intractable tinnitus. ENT J. 74: 468-476, 1995.
95. RAJAN, R., IRVINE, D.R.F., WISE, L. Z., AND HEIL, P. Effect of unilateral partial cochlear lesions in adult cats on the representation of lesioned and unlesioned cochleas in primary auditory cortex. J. Comp. Neurol. 338: 17-49, 1993.
96. RAVICZ, M. E. AND MELCHER, J. R. Imager noise and noise attenuation during fMRI. Neuroimage 7: S556, 1998.
97. RAVICZ, M. E., MELCHER, J. R., TALAVAGE, T. M., BENSON, R. R., ROSEN, B. R., AND KIANG, N.Y.S. Characterization and reduction of imager generated noise during functional magnetic resonance imaging (fMRI) (Abstract). Assoc. Res. Otolaryngol. 20: 205, 1997.
98. REED, G. F. An audiometric study of two hundred cases of subjective tinnitus. Arch. Otolaryngol. 71: 94-104, 1960.
99. REESE, T. G., DAVIS, T. L., AND WEISSKOFF, R. M. Automated shimming at 1.5T using echo-planar image frequency maps. J. Magn. Reson. Imag. 5: 739-745, 1995.
100. ROBERTSON, D., AND IRVINE, D.R.F. Plasticity of frequency organization in auditory cortex of guinea pigs with partial unilateral deafness. J. Comp. Neurol. 282: 456-471, 1989.
101. ROBSON, M. D., DOROSZ, J. L., AND GORE, J. C. Measurements of the temporal fMRI response of the human auditory cortex to trains of tones. Neuroimage 7: 185-198, 1998.
102. ROSENHALL, U. AND AXELSSON, A. Auditory brainstem response latenceis in patients with tinnitus. Scand. Audiol. 24: 97-100, 1995.
103. ROSENHAMER, H. The auditory evoked brainstem electric response (ABR) in cochlear hearing loss. Scand. Audiol. Suppl. 13: 83-93, 1981.
104. RUBINSTEIN, B., AXELSSON, A., AND CARLSSON, G. E. Prevalence of signs and symptoms of craniomandibular disorders in tinnitus patients. J. Craniomandibular Disord. Facial Oral Pain 4: 186-192, 1990.
105. 14C]2-deoxyglucose uptake after deafferentation of the mammalian auditory pathway-a model for examining tinnitus. Brain Res. 194: 511-516, 1980.
106. SCHREINER, C. E. AND SNYDER, R. L. A physiological animal model of peripheral tinnitus. In: Proceedings of the Third International Tinnitus Seminar, edited by H. Feldmann. Munster, Germany: Harsch Verlag Karlsruhe, 1987, p. 100-106.
107. SCHWABER, M. K., GARRAGHTY, P. E., AND KAAS, J. H. Neuroplasticity of the adult primate auditory cortex following cochlear hearing loss. Am. J. Otol. 14: 252-258, 1993.
108. SHIOMI, Y., NAGAMINE, T., FUJIKI, N., HIRANO, S., NAITO, Y., SHIBASAKI, H., AND HONJO, I. Tinnitus remission by lidocaine demonstrated by auditory-evoked magnetoencephalogram. Acta Otolaryngol. 117: 31-34, 1997.
109. SISMANIS, A. AND SMOKER, W. Pulsatile tinnitus: recent advances in diagnosis. Laryngoscope 104: 681-688, 1994.
110. STEFANACCI, L., REBER, P., COSTANZA, J., WONG, E., BUXTON, R., ZOLA, S., SQUIRE, L., AND ALBRIGHT, T. fMRI of monkey visual cortex. Neuron 20: 1051-1057, 1998.
111. STYPULKOWSKI, P. H. Mechanisms of salicylate ototoxicity. Hear. Res. 46: 113-146, 1990.
112. TALAVAGE, T. M., EDMISTER, W. B., LEDDEN, P. J., AND WEISKOFF, R. M. Quantitative assessment of auditory cortex responses induced by imager acoustic noise. Hum. Brain Mapp. 7: 79-88, 1999.
113. TYLER, R. S. Perspectives on tinnitus. Br. J. Audiol. 31: 381-386, 1997.
114. VAN NOORT, J. The Structure and Connections of the Inferior Colliculus. Assen, The Netherlands: Van Gorcum. 1969.
115. WALL, M., ROSENBERG, M., AND RICHARDSON, D. Gaze-evoked tinnitus. Neurology 37: 1034-1036, 1987.
116. WALLHÄUSSER-FRANKE, E., BRAUN, S., AND LANGNER, G. Salicylate alters 2-DG uptake in the auditory system: a model for tinnitus? Neuroreport 7: 1585-1588, 1996.
117. WALLHÄUSSER-FRANKE, E. Salicylate evokes c-fos expression in the brain stem: implications for tinnitus. Neuroreport 8: 725-728, 1997.
118. WILLOTT, J. F., AITKIN, L. M., AND MCFADDEN, S. L. Plasticity of auditory cortex associated with sensorineural hearing loss in adult C57BL/6J mice. J. Comp. Neurol. 329: 402-411, 1993.
119. ZHANG, J. S. AND KALTENBACH, J. A. Increases in spontaneous activity in the dorsal cochlear nucleus of the rat following exposure to high-intensity sound. Neurosci. Lett. 250: 197-200, 1998.