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Volumn 106, Issue 2, 2012, Pages 414-423

DNA methylation profiles delineate epigenetic heterogeneity in seminoma and non-seminoma

Author keywords

biomarker; DNA methylation; epigenetics; non seminoma; seminoma; testicular cancer

Indexed keywords

APC PROTEIN; ARF PROTEIN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; PROTEIN MLH1;

EID: 84856425020     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2011.468     Document Type: Article
Times cited : (52)

References (50)
  • 1
    • 0029122814 scopus 로고
    • Loss of heterozygosity on chromosome arms 5q, 11p, 11q, 13q, and 16p in human testicular germ cell tumors
    • Al-Jehani RM, Povey S, Delhanty JD, Parrington JM (1995) Loss of heterozygosity on chromosome arms 5q, 11p, 11q, 13q, and 16p in human testicular germ cell tumors. Genes Chromosomes Cancer 13: 249-256
    • (1995) Genes Chromosomes Cancer , vol.13 , pp. 249-256
    • Al-Jehani, R.M.1    Povey, S.2    Delhanty, J.D.3    Parrington, J.M.4
  • 2
    • 0030857028 scopus 로고    scopus 로고
    • Testicular germ-cell cancer
    • Bosl GJ, Motzer RJ (1997) Testicular germ-cell cancer. N Engl J Med 337: 242-253
    • (1997) N Engl J Med , vol.337 , pp. 242-253
    • Bosl, G.J.1    Motzer, R.J.2
  • 7
    • 36549019974 scopus 로고    scopus 로고
    • Somatic KIT mutations occur predominantly in seminoma germ cell tumors and are not predictive of bilateral disease: Report of 220 tumors and review of literature
    • DOI 10.1002/gcc.20503
    • Coffey J, Linger R, Pugh J, Dudakia D, SokalM, Easton DF, Timothy Bishop D, Stratton M, Huddart R, Rapley EA (2008) Somatic KIT mutations occur predominantly in seminoma germ cell tumors and are not predictive of bilateral disease: report of 220 tumors and review of literature. Genes Chromosomes Cancer 47: 34-42 (Pubitemid 350191462)
    • (2008) Genes Chromosomes and Cancer , vol.47 , Issue.1 , pp. 34-42
    • Coffey, J.1    Linger, R.2    Pugh, J.3    Dudakia, D.4    Sokal, M.5    Easton, D.F.6    Bishop, D.T.7    Stratton, M.8    Huddart, R.9    Rapley, E.A.10
  • 8
    • 0023710206 scopus 로고
    • Comparing the areas under two or more correlated receiver operating characteristic curves: A nonparametric approach
    • DeLong ER, DeLong DM, Clarke-Pearson DL (1988) Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics 44: 837-845
    • (1988) Biometrics , vol.44 , pp. 837-845
    • Delong, E.R.1    Delong, D.M.2    Clarke-Pearson, D.L.3
  • 9
    • 66749190952 scopus 로고    scopus 로고
    • CpG island hypermethylation of cell-free circulating serum DNA in patients with testicular cancer
    • Ellinger J, Albers P, Perabo FG, Muller SC, von Ruecker A, Bastian PJ (2009) CpG island hypermethylation of cell-free circulating serum DNA in patients with testicular cancer. J Urol 182: 324-329
    • (2009) J Urol , vol.182 , pp. 324-329
    • Ellinger, J.1    Albers, P.2    Perabo, F.G.3    Muller, S.C.4    Von Ruecker, A.5    Bastian, P.J.6
  • 10
    • 79953798790 scopus 로고    scopus 로고
    • Down-regulation of oestrogen receptorbeta associates with transcriptional co-regulator PATZ1 delocalization in human testicular seminomas
    • Esposito F, Boscia F, Franco R, Tornincasa M, Fusco A, Kitazawa S, Looijenga LH, Chieffi P (2010) Down-regulation of oestrogen receptorbeta associates with transcriptional co-regulator PATZ1 delocalization in human testicular seminomas. J Pathol 224: 110-120
    • (2010) J Pathol , vol.224 , pp. 110-120
    • Esposito, F.1    Boscia, F.2    Franco, R.3    Tornincasa, M.4    Fusco, A.5    Kitazawa, S.6    Looijenga, L.H.7    Chieffi, P.8
  • 11
    • 0035870248 scopus 로고    scopus 로고
    • A gene hypermethylation profile of human cancer
    • Esteller M, Corn PG, Baylin SB, Herman JG (2001) A gene hypermethylation profile of human cancer. Cancer Res 61: 3225-3229 (Pubitemid 32695003)
    • (2001) Cancer Research , vol.61 , Issue.8 , pp. 3225-3229
    • Esteller, M.1    Corn, P.G.2    Baylin, S.B.3    Herman, J.G.4
  • 14
    • 67650831963 scopus 로고    scopus 로고
    • The dynamic epigenetic program in male germ cells: Its role in spermatogenesis, testis cancer, and its response to the environment
    • Godmann M, Lambrot R, Kimmins S (2009) The dynamic epigenetic program in male germ cells: Its role in spermatogenesis, testis cancer, and its response to the environment. Microsc Res Tech 72: 603-619
    • (2009) Microsc Res Tech , vol.72 , pp. 603-619
    • Godmann, M.1    Lambrot, R.2    Kimmins, S.3
  • 15
    • 0032731581 scopus 로고    scopus 로고
    • Hypermethylation of tumor suppressor genes in cancer
    • DOI 10.1006/scbi.1999.0138
    • Herman JG (1999) Hypermethylation of tumor suppressor genes in cancer. Semin Cancer Biol 9: 359-367 (Pubitemid 29532862)
    • (1999) Seminars in Cancer Biology , vol.9 , Issue.5 , pp. 359-367
    • Herman, J.G.1
  • 19
    • 0037461896 scopus 로고    scopus 로고
    • Frequent epigenetic inactivation of the RASSF1A tumour suppressor gene in testicular tumours and distinct methylation profiles of seminoma and nonseminoma testicular germ cell tumours
    • DOI 10.1038/sj.onc.1206119
    • Honorio S, Agathanggelou A, Wernert N, Rothe M, Maher ER, Latif F (2003) Frequent epigenetic inactivation of the RASSF1A tumour suppressor gene in testicular tumours and distinct methylation profiles of seminoma and nonseminoma testicular germ cell tumours. Oncogene 22: 461-466 (Pubitemid 36194343)
    • (2003) Oncogene , vol.22 , Issue.3 , pp. 461-466
    • Honorio, S.1    Agathanggelou, A.2    Wernert, N.3    Rothe, M.4    Maher, E.R.5    Latif, F.6
  • 20
    • 3442894720 scopus 로고    scopus 로고
    • Quantitative detection of promoter hypermethylation of multiple genes in the tumor, urine, and serum DNA of patients with renal cancer
    • DOI 10.1158/0008-5472.CAN-04-0799
    • Hoque MO, Begum S, Topaloglu O, Jeronimo C, Mambo E, Westra WH, Califano JA, Sidransky D (2004) Quantitative detection of promoter hypermethylation of multiple genes in the tumor, urine, and serum DNA of patients with renal cancer. Cancer Res 64: 5511-5517 (Pubitemid 39006576)
    • (2004) Cancer Research , vol.64 , Issue.15 , pp. 5511-5517
    • Hoque, M.O.1    Begum, S.2    Topaloglu, O.3    Jeronimo, C.4    Mambo, E.5    Westra, W.H.6    Califano, J.A.7    Sidransky, D.8
  • 22
    • 33644648880 scopus 로고    scopus 로고
    • Testicular germ-cell cancer
    • DOI 10.1016/S0140-6736(06)68305-0, PII S0140673606683050
    • Horwich A, Shipley J, Huddart R (2006) Testicular germ-cell cancer. Lancet 367: 754-765 (Pubitemid 43326294)
    • (2006) Lancet , vol.367 , Issue.9512 , pp. 754-765
    • Horwich, A.1    Shipley, J.2    Huddart, R.3
  • 24
    • 33646187811 scopus 로고    scopus 로고
    • The multifaceted mismatch-repair system
    • Jiricny J (2006) The multifaceted mismatch-repair system. Nat Rev Mol Cell Biol 7: 335-346
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 335-346
    • Jiricny, J.1
  • 27
    • 77956818209 scopus 로고    scopus 로고
    • Reversibility of premalignant estrogen-induced epigenetic changes
    • Kutanzi KR, Koturbash I, Kovalchuk O. (2010) Reversibility of premalignant estrogen-induced epigenetic changes. Cell Cycle 9: 3078-3084
    • (2010) Cell Cycle , vol.9 , pp. 3078-3084
    • Kutanzi, K.R.1    Koturbash, I.2    Kovalchuk, O.3
  • 29
    • 0037112447 scopus 로고    scopus 로고
    • Promoter hypermethylation of the death-associated protein kinase gene in breast cancer is associated with the invasive lobular subtype
    • Lehmann U, Celikkaya G, Hasemeier B, Langer F, Kreipe H (2002) Promoter hypermethylation of the death-associated protein kinase gene in breast cancer is associated with the invasive lobular subtype. Cancer Res 62: 6634-6638 (Pubitemid 35364131)
    • (2002) Cancer Research , vol.62 , Issue.22 , pp. 6634-6638
    • Lehmann, U.1    Celikkaya, G.2    Hasemeier, B.3    Langer, F.4    Kreipe, H.5
  • 30
    • 36549060957 scopus 로고    scopus 로고
    • The epigenome of testicular germ cell tumors
    • DOI 10.1111/j.1600-0463.2007.apm-660.xml.x
    • Lind GE, Skotheim RI, Lothe RA (2007) The epigenome of testicular germ cell tumors. Apmis 115: 1147-1160 (Pubitemid 350179475)
    • (2007) APMIS , vol.115 , Issue.10 , pp. 1147-1160
    • Lind, G.E.1    Skotheim, R.I.2    Lothe, R.A.3
  • 31
    • 66949163989 scopus 로고    scopus 로고
    • Human testicular (non)seminomatous germ cell tumours: The clinical implications of recent pathobiological insights
    • Looijenga LH (2009) Human testicular (non)seminomatous germ cell tumours: the clinical implications of recent pathobiological insights. J Pathol 218: 146-162
    • (2009) J Pathol , vol.218 , pp. 146-162
    • Looijenga, L.H.1
  • 34
    • 0031717092 scopus 로고    scopus 로고
    • Testicular germ cell tumors: Molecular understanding and clinical implications
    • DOI 10.1016/S1357-4310(98)01329-X, PII S135743109801329X
    • Lutzker SG, Barnard NJ (1998) Testicular germ cell tumors: molecular understanding and clinical implications. Mol Med Today 4: 404-411 (Pubitemid 28411035)
    • (1998) Molecular Medicine Today , vol.4 , Issue.9 , pp. 404-411
    • Lutzker, S.G.1    Barnard, N.J.2
  • 36
    • 0028046406 scopus 로고
    • Loss of heterozygosity identifies multiple sites of allelic deletions on chromosome 1 in human male germ cell tumors
    • Mathew S, Murty VV, Bosl GJ, Chaganti RS (1994) Loss of heterozygosity identifies multiple sites of allelic deletions on chromosome 1 in human male germ cell tumors. Cancer Res 54: 6265-6269 (Pubitemid 24378663)
    • (1994) Cancer Research , vol.54 , Issue.23 , pp. 6265-6269
    • Mathew, S.1    Murty, V.V.V.S.2    Bosl, G.J.3    Chaganti, R.S.K.4
  • 38
    • 0038543444 scopus 로고    scopus 로고
    • Methylation of the cyclin A1 promoter correlates with gene silencing in somatic cell lines, while tissue-specific expression of cyclin A1 is methylation independent
    • DOI 10.1128/MCB.20.9.3316-3329.2000
    • Muller C, Readhead C, Diederichs S, Idos G, Yang R, Tidow N, Serve H, Berdel WE, Koeffler HP (2000) Methylation of the cyclin A1 promoter correlates with gene silencing in somatic cell lines, while tissue-specific expression of cyclin A1 is methylation independent. Mol Cell Biol 20: 3316-3329 (Pubitemid 30215043)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.9 , pp. 3316-3329
    • Muller, C.1    Readhead, C.2    Diederichs, S.3    Idos, G.4    Yang, R.5    Tidow, N.6    Serve, H.7    Berdel, W.E.8    Koeffler, H.P.9
  • 40
    • 27944448740 scopus 로고    scopus 로고
    • Influence of hMLH1 methylation, mismatch repair deficiency and microsatellite instability on chemoresistance of testicular germ-cell tumors
    • Olasz J, Mandoky L, Geczi L, Bodrogi I, Csuka O, Bak M (2005) Influence of hMLH1 methylation, mismatch repair deficiency and microsatellite instability on chemoresistance of testicular germ-cell tumors. Anticancer Res 25: 4319-4324 (Pubitemid 41665223)
    • (2005) Anticancer Research , vol.25 , Issue.6 B , pp. 4319-4324
    • Olasz, J.1    Mandoky, L.2    Geczi, L.3    Bodrogi, I.4    Csuka, O.5    Bak, M.6
  • 41
    • 14644396631 scopus 로고    scopus 로고
    • Testicular germ-cell tumours in a broader perspective
    • DOI 10.1038/nrc1568
    • Oosterhuis JW, Looijenga LH (2005) Testicular germ-cell tumours in a broader perspective. Nat Rev Cancer 5: 210-222 (Pubitemid 40314952)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.3 , pp. 210-222
    • Oosterhuis, J.W.1    Looijenga, L.H.J.2
  • 42
  • 43
    • 0025755712 scopus 로고
    • DNA methylation changes in human testicular cancer
    • Peltomaki P (1991) DNA methylation changes in human testicular cancer. Biochim Biophys Acta 1096: 187-196
    • (1991) Biochim Biophys Acta , vol.1096 , pp. 187-196
    • Peltomaki, P.1
  • 44
    • 33645835375 scopus 로고    scopus 로고
    • Developmental model for the pathogenesis of testicular carcinoma in situ: Genetic and environmental aspects
    • Rajpert-De Meyts E (2006) Developmental model for the pathogenesis of testicular carcinoma in situ: genetic and environmental aspects. Hum Reprod Update 12: 303-323
    • (2006) Hum Reprod Update , vol.12 , pp. 303-323
    • Rajpert-De Meyts, E.1
  • 45
    • 35948981194 scopus 로고    scopus 로고
    • Association between DNA methylation and shortened survival in patients with advanced colorectal cancer treated with 5-fluorouracil-based chemotherapy
    • DOI 10.1158/1078-0432.CCR-07-1011
    • Shen L, Catalano PJ, Benson III AB, O'Dwyer P, Hamilton SR, Issa JP (2007) Association between DNA methylation and shortened survival in patients with advanced colorectal cancer treated with 5-fluorouracil based chemotherapy. Clin Cancer Res 13: 6093-6098 (Pubitemid 350075067)
    • (2007) Clinical Cancer Research , vol.13 , Issue.20 , pp. 6093-6098
    • Shen, L.1    Catalano, P.J.2    Benson III, A.B.3    O'Dwyer, P.4    Hamilton, S.R.5    Issa, J.-P.J.6
  • 46
    • 85047696878 scopus 로고    scopus 로고
    • Distinct epigenetic phenotypes in seminomatous and nonseminomatous testicular germ cell tumors
    • DOI 10.1038/sj/onc/1205488
    • Smiraglia DJ, Szymanska J, Kraggerud SM, Lothe RA, Peltomaki P, Plass C (2002) Distinct epigenetic phenotypes in seminomatous and nonseminomatous testicular germ cell tumors. Oncogene 21: 3909-3916 (Pubitemid 34620859)
    • (2002) Oncogene , vol.21 , Issue.24 , pp. 3909-3916
    • Smiraglia, D.J.1    Szymanska, J.2    Kraggerud, S.M.3    Lothe, R.A.4    Peltomaki, P.5    Plass, C.6
  • 48
    • 34248220409 scopus 로고    scopus 로고
    • Testis cancer
    • DOI 10.1016/j.juro.2007.01.127, PII S0022534707002650
    • Sokoloff MH, Joyce GF, Wise M (2007) Testis cancer. J Urol 177: 2030-2041 (Pubitemid 46726398)
    • (2007) Journal of Urology , vol.177 , Issue.6 , pp. 2030-2041
    • Sokoloff, M.H.1    Joyce, G.F.2    Wise, M.3
  • 49
    • 0033535612 scopus 로고    scopus 로고
    • A role for methylation of the hMLH1 promoter in loss of hMLH1 expression and drug resistance in ovarian cancer
    • Strathdee G, MacKean MJ, Illand M, Brown R (1999) A role for methylation of the hMLH1 promoter in loss of hMLH1 expression and drug resistance in ovarian cancer. Oncogene 18: 2335-2341 (Pubitemid 29192710)
    • (1999) Oncogene , vol.18 , Issue.14 , pp. 2335-2341
    • Strathdee, G.1    MacKean, M.J.2    Illand, M.3    Brown, R.4


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