Global DNA methylation in fetal human germ cells and germ cell tumours: Association with differentiation and cisplatin resistance

Journal of Pathology

Volumn 221, Issue 4, 2010, Pages 433-442

  Wermann, Hendrik ^a,b   Stoop, Hans ^a   Gillis, Ad J M ^a   Honecker, Friedemann ^b   Van Gurp, Ruud J H L M ^a   Ammerpohl, Ole ^c   Richter, Julia ^c   Oosterhuis, J Wolter ^a   Bokemeyer, Carsten ^b   Looijenga, Leendert H J ^a  

^a JOSEPHINE NEFKENS INSTITUTE   (Netherlands)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^c UNIVERSITY OF KIEL   (Germany)

Author keywords

5 azacytidine; Cisplatin resistance; Differentiation; DNA methylation; Germ cell tumours

Indexed keywords

AZACITIDINE; BONE MORPHOGENETIC PROTEIN RECEPTOR 1A; CELL MARKER; CISPLATIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; FLICE INHIBITORY PROTEIN; KRUPPEL LIKE FACTOR; OCTAMER TRANSCRIPTION FACTOR 4; SMAD4 PROTEIN; TRANSCRIPTION FACTOR NANOG;

ADULT; ARTICLE; CANCER RESISTANCE; CHORIOCARCINOMA; CLINICAL ASSESSMENT; CORRELATION ANALYSIS; DEMETHYLATION; DNA FINGERPRINTING; DNA METHYLATION; DRUG RESISTANCE; DYSGERMINOMA; EMBRYONAL CARCINOMA; FEMALE; FETUS; FETUS CELL; GENE EXPRESSION; GERM CELL; GONADOBLASTOMA; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INFANT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN ISOLATION; SEMINOMA; TERATOMA; TUMOR DIFFERENTIATION; TUMOR SUPPRESSOR GENE; YOLK SAC TUMOR;

ADULT; ANTIMETABOLITES, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS; AZACITIDINE; CELL DIFFERENTIATION; CISPLATIN; DEAD-BOX RNA HELICASES; DNA METHYLATION; DNA, NEOPLASM; DRUG RESISTANCE, NEOPLASM; FEMALE; FETUS; GENE EXPRESSION REGULATION, NEOPLASTIC; GERM CELLS; HUMANS; IMMUNOENZYME TECHNIQUES; INFANT; MALE; NEOPLASM PROTEINS; NEOPLASMS, GERM CELL AND EMBRYONAL; OVARY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEMINOMA; TESTICULAR NEOPLASMS; TESTIS;

EID: 77955504268     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2725     Document Type: Article

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